Cefiderocol

This active molecular is a potent cephalosporin antibiotic with a catechol moiety on the 3-position side chain under the development of Shionogi. Cefiderocol exhibits potent activity against the non-fermenting Gram-negative bacteria in vitro including Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia. Now Cefiderocol is in clinical Phase III for treatment of severe infections caused by Carbapenem-resistant Gram-negative pathogens.

• Supplier: BOC Sciences
• Product #: B0084-475177
• Cas: 1225208-94-5
• Molecular Weight: 752.22
• Molecular Formula: C30H34ClN7O10S2
• Canonical SMILES: CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)[O-])C[N+]3(CCNC(=O)c4ccc(O)c(O)c4Cl)CCCC3)\c5csc(N)n5)C(=O)O