W-54011
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16992A-5 mg |
| CAS # | 405098-33-1 |
| Pricing | 5 mg, USD $192.0 |
| Biological Activity | W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3.1 nM, 2.7 nM, and 1.6 nM, respectively[1]. |
| Purity | ≥98.0% |
| MWt | 493.08 |
| Formula | C₃₀H₃₇ClN₂O₂ |