BRD 4354
BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM).
| Supplier | BOC Sciences |
|---|---|
| Product # | B2693-119062 |
| Pricing | Inquire |
| Cas | 315698-07-8 |
| Molecular Weight | 382.89 |
| Molecular Formula | C21H23ClN4O |
| Canonical SMILES | CCN1CCN(CC1)C(C2=CN=CC=C2)C3=CC(=C4C=CC=NC4=C3O)Cl |