LY3214996
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-101494-10 mM * 1 mL |
| CAS # | 1951483-29-6 |
| Pricing | 10 mM * 1 mL, USD $239.0 |
| Biological Activity | LY3214996 is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. LY3214996 potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. LY3214996 shows potent antitumor activities in cancer models with MAPK pathway alterations. |
| Purity | 99.54% |
| MWt | 453.56 |
| Formula | C₂₂H₂₇N₇O₂S |