Trametinib (DMSO solvate)
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10999A-10 mM * 1 mL |
| CAS # | 1187431-43-1 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate) |
| MWt | 693.53 |
| Formula | C₂₈H₂₉FIN₅O₅S |
| Biological Activity | Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis[1][2]. |
| Purity | 99.77% |