Polygalacin D

• Supplier: MedChemExpress
• Product #: HY-N6064-5 mg
• CAS #: 66663-91-0
• Biological Activity:
  • Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum (Jacq.) with anticancer and anti-proliferative properties.
  • PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis[1]
• Purity: ≥99.0%
• MWt: 1209.32
• Formula: C₅₇H₉₂O₂₇