Brevetoxin B
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12546 |
| CAS # | 79580-28-2 |
| Pricing | inquire |
| Biological Activity | Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Brevetoxin B binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50=15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. |
| Synonyms | Brevetoxin-2; PbTx-2 |
| MWt | 895.08 |
| Formula | C₅₀H₇₀O₁₄ |