cyclic-guanylate-specific phosphodiesterase

Requires Mg2+ or Mn2+ for activity and is inhibited by Ca2+ and Zn2+. Contains a heme unit. This enzyme linearizes cyclic di-3,5-guanylate, the product of EC 2.7.7.65, diguanylate cyclase and an allosteric activator of EC 2.4.1.12, cellulose synthase (UDP-forming), rendering it inactive. It is the balance between these two enzymes that determines the cellular level of c-di-GMP.
Supplier Creative Enzymes
Product # EXWM-3735
Pricing 100 ug, contact supplier for pricing
CAS 338732-46-0
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