Recombinant Human Anti-SARS S Antibody (80R)
Recombinant Human Antibody (80R) is capable of binding to SARS S, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SARS S mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-SARS S proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. We show that the 80R-binding epitope on the S1 RBD overlaps very closely with the ACE2 binding site, providing a rationale for the strong binding and broad neutralizing ability of the antibody.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABZ-139 |
| Pricing | Inquiry |
| Host | Human |
| Target | SARS S |
| Species Reactivity | SARS |
| Type | IgG |
| Applications |
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| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |