Resatorvid
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-11109-10 mM * 1 mL |
| CAS # | 243984-11-4 |
| Pricing | 10 mM * 1 mL, USD $145.0 |
| Synonyms | TAK-242; CLI-095 |
| MWt | 361.82 |
| Formula | C₁₅H₁₇ClFNO₄S |
| Biological Activity | Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases[1][2]. |
| Purity | 99.95% |