Indibulin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13649-50 mg |
| CAS # | 204205-90-3 |
| Pricing | 50 mg, USD $580.0 |
| Synonyms | ZIO 301; D 24851 |
| MWt | 389.83 |
| Formula | C₂₂H₁₆ClN₃O₂ |
| Biological Activity | Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis[1]. |
| Purity | 99.61% |