Upadacitinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19569-50 mg |
| CAS # | 1310726-60-3 |
| Pricing | 50 mg, USD $390.0 |
| Synonyms | ABT-494 |
| MWt | 380.37 |
| Formula | C₁₇H₁₉F₃N₆O |
| Biological Activity | Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) is used in development for the treatment of several autoimmune disorders[1][2]. |
| Purity | 99.96% |