INDY
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108476-5 mg |
| CAS # | 1169755-45-6 |
| Pricing | 5 mg, USD $270.0 |
| Biological Activity | INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells[1][2]. |
| MWt | 235.3 |
| Formula | C₁₂H₁₃NO₂S |