Samuraciclib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-103712A-10 mM * 1 mL |
| CAS # | 1805789-54-1 |
| Pricing | 10 mM * 1 mL, USD $284.0 |
| Synonyms | CT7001 hydrochloride; ICEC0942 hydrochloride |
| MWt | 430.97 |
| Formula | C₂₂H₃₁ClN₆O |
| Biological Activity | Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 µM. Samuraciclib hydrochloride has anti-tumor effects[1][2]. |
| Purity | 99.98% |