ARQ-621
ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1095253-39-6 |
| Pricing | Inquire |
| Cas | 1095253-39-6 |
| Molecular Weight | 552.43 |
| Molecular Formula | C28H24Cl2FN5O2 |
| Canonical SMILES | C#CCC(C1=NC2=C(C=CC(=C2)Cl)C(=O)N1NC3=CC=CC=C3)N(CCCN)C(=O)C4=C(C(=CC=C4)Cl)F |