Cucurbitacin IIb
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N1987-10 mM * 1 mL |
| CAS # | 50298-90-3 |
| Pricing | 10 mM * 1 mL, USD $308.0 |
| Biological Activity | Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1]. |
| Purity | ≥99.0% |
| MWt | 520.7 |
| Formula | C₃₀H₄₈O₇ |