Copanlisib dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15346A-50 mg |
| CAS # | 1402152-13-9 |
| Pricing | 50 mg, USD $270.0 |
| Synonyms | BAY 80-6946 dihydrochloride |
| MWt | 553.44 |
| Formula | C₂₃H₃₀Cl₂N₈O₄ |
| Biological Activity | Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib dihydrochloride has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib dihydrochloride has superior antitumor activity[1]. |
| Purity | 99.55% |