Hexacyclinol

Hexacycline is a natural metabolite of the fungus Panus rudis HKI 0254. It has moderate anti-Gram-positive bacteria activity, 4-40μg/mL can inhibit the production of oxidants by polymorphonuclear neutrophils (PMNL) stimulated by zymosan. It inhibits the growth of L-930 and K 562 cells with IC50 of 1.4μg/mL and 0.4μg/mL, respectively, and the IC50 of HeLa cells is 10μg/mL. It also has an anti-Plasmodium effect, and its IC50 for Plasmodium falciparum is 2.4μg/mL.

• Supplier: BOC Sciences
• Product #: BBF-00951
• Molecular Weight: 416.47
• Molecular Formula: C23H28O7
• Canonical SMILES: CC(=CC1C23C(C=C4C(C2C(O1)C5C(C3=O)O5)C(C6C(C4=O)O6)O)C(C)(C)OC)C