mDPR-Val-Cit-PAB-MMAE
| Supplier | Creative Peptides |
|---|---|
| Product # | R1901 |
| CAS # | 1491152-26-1 |
| Pricing | Inquire |
| MolecularFormula | C65H100N12O15 |
| MolecularWeight | 1289.56 |
| Explanation | mDPR-Val-Cit-PAB-MMAE consists the ADCs linker (mDPR-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), mDPR-Val-Cit-PAB-MMAE is an antibody drug conjugate. |
| ChemicalName | N-[(2S)-3-Amino-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl]-L-valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2 ;-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide |
| Application | Antibody-drug Conjugate |
| CanonicalSMILES | O=C([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N1C(C=CC1=O)=O)CN)=O)=O)NC2=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N3[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C4=CC=CC=C4)C)=O)C)CCC3)=O)OC)[C@@H](C)CC)C)=O)=O)=O)C=C2 |