Sotorasib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-114277-5 mg |
| CAS # | 2296729-00-3 |
| Pricing | 5 mg, USD $90.0 |
| Synonyms | AMG-510 |
| MWt | 560.59 |
| Formula | C₃₀H₃₀F₂N₆O₃ |
| Biological Activity | Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors[1][2]. |
| Purity | 99.60% |