M8891
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133016-100 mg |
| CAS # | 1464842-09-8 |
| Pricing | 100 mg, USD $5000.0 |
| Biological Activity | M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 54 nM and a Ki of 4.33 nM. M8891 does not inhibit MetAP-1 (IC50>10 µM)[1]. M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral activity[2]. |
| Purity | 98.74% |
| MWt | 385.36 |
| Formula | C₂₀H₁₇F₂N₃O₃ |