E7820

Supplier MedChemExpress
Product # HY-14571-10 mg
CAS # 289483-69-8
Pricing 10 mg, USD $140.0
Synonyms ER68203-00
MWt 336.37
Formula C₁₇H₁₂N₄O₂S
Biological Activity E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity[1][2].
Purity 99.36%
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