Setrobuvir (ANA598)
Setrobuvir (ANA598) is an orally active non-nucleosidic HCV NS5B polymerase inhibitor. ANA-598 inhibits both de novo RNA synthesis and primer extension, with IC50s between 4 and 5 nM. Setrobuvir also shows excellent binding affinity to SARS- CoV-2 RdRp and induces RdRp inhibition.
Supplier | BOC Sciences |
---|---|
Product # | 1071517-39-9 |
Pricing | Inquire |
Cas | 1071517-39-9 |
Molecular Weight | 560.617603 |
Molecular Formula | C25H25FN4O6S2 |
Canonical SMILES | CS(=O)(=O)NC1=CC2=C(C=C1)NC(=C3C(=O)C4C5CCC(C5)C4N(C3=O)CC6=CC=C(C=C6)F)NS2(=O)=O |