NITD-916
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-122643 |
| CAS # | 1614262-83-7 |
| Pricing | inquire |
| Biological Activity | NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilic mycobacterial enoyl reductase InhA inhibitor with an IC50 of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 has potent anti-tuberculosis effects[1][2]. |
| MWt | 311.42 |
| Formula | C₂₀H₂₅NO₂ |