GS143
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-110261-50 mg |
| CAS # | 916232-21-8 |
| Pricing | 50 mg, USD $500.0 |
| Biological Activity | GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes and does not inhibit proteasome activity. GS143 has anti-asthma effect[1][2]. |
| Purity | 98.30% |
| MWt | 466.46 |
| Formula | C₂₈H₁₉FN₂O₄ |