Larotrectinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12866-10 mg |
| CAS # | 1223403-58-4 |
| Pricing | 10 mg, USD $144.0 |
| Synonyms | LOXO-101; ARRY-470 |
| MWt | 428.44 |
| Formula | C₂₁H₂₂F₂N₆O₂ |
| Biological Activity | Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). |
| Purity | 99.93% |