GSK778
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-136570-100 mg |
| CAS # | 2451862-42-1 |
| Pricing | 100 mg, USD $6500.0 |
| Synonyms | iBET-BD1 |
| MWt | 511.61 |
| Formula | C₃₀H₃₃N₅O₃ |
| Biological Activity | GSK778 (iBET-BD1) is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 phenocopies the effects of pan-BET inhibitors in cancer models[1]. |
| Purity | 98.58% |