Tyk2-IN-5
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-111745-50 mg |
| CAS # | 1797432-62-2 |
| Pricing | 50 mg, USD $2250.0 |
| Biological Activity | Tyk2-IN-5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0.086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFNα. Highly effective in inhibiting IFNγ production in a rat pharmacodynamics model and fully efficacious in a rat adjuvant arthritis model[1]. |
| Purity | 99.78% |
| MWt | 434.43 |
| Formula | C₂₁H₁₉FN₈O₂ |