5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite

5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a cytidine base modified with an acetyl (Ac) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is employed in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.

• Supplier: BOC Sciences
• Product #: BRP-00409
• Molecular Weight: 899.03
• Molecular Formula: C46H51N4O9PS2
• Canonical SMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC