Raloxifene 6-glucuronide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-135581 |
| CAS # | 174264-50-7 |
| Pricing | inquire |
| Biological Activity | Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[1][2][3]. |
| MWt | 649.71 |
| Formula | C₃₄H₃₅NO₁₀S |