Human 26S Proteasome Regulatory Subunit 10B (PSMC6) Protein
Recombinant 26S Proteasome Regulatory Subunit 10B (PSMC6) is a recombinant Human protein produced in E. coli using Prokaryotic expression. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx068722-5MG |
| Pricing | 5 mg USD $6148.0 |
| Conjugation | Unconjugated |
| Host | E. coli |
| Tested Applications | WB, SDS-PAGE |
| UniProt Primary AC | P62333 |
| Activity | Not tested |
| Dry Ice | No |
| Availability | Shipped within 5-7 working days. |
| Note |
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