NPS-2143 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10171-10 mM * 1 mL |
| CAS # | 324523-20-8 |
| Pricing | 10 mM * 1 mL, USD $114.0 |
| Synonyms | SB-262470A hydrochloride |
| MWt | 445.38 |
| Formula | C₂₄H₂₆Cl₂N₂O₂ |
| Biological Activity | NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2]. |
| Purity | 99.94% |