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1 - 9 of 9 citations for SSP SAP since 2019

• Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation

  Stephen P. Persaud, et al., bioRxiv - Immunology 2020

  Quote: ... non-interaction of these two components was ensured by using non-biotinylated antibodies and sAV-SAP whose biotin-binding sites were occupied by an irrelevant biotinylated 11-mer peptide (BLANK Streptavidin-SAP, Advanced Targeting Systems). For experiments in which free antibody or sAV-SAP were administered alone ...
• Exaggerated postnatal surge of orexin and the effects of elimination of excess orexin on blood pressure in spontaneously hypertensive rats in postnatal development

  Savannah Barnett, et al., bioRxiv - Neuroscience 2020

  Quote: ... Hcrt-SAP (hypocretin-2-saporin, Advanced Targeting Systems, San Diego, CA, USA). The method of stereotaxic injection was similar to those described in our previous study and will be brief here (Nattie et al. ...
• Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation

  Stephen P. Persaud, et al., bioRxiv - Immunology 2020

  Quote: Saporin conjugated to streptavidin (sAV-SAP; Advanced Targeting Systems, San Diego, CA) was used to indirectly couple biotinylated antibodies to saporin to generate the ADCs used in this study ...
• BNP facilitates NMB-mediated histaminergic itch via NPRC-NMBR crosstalk

  Qing-Tao Meng, et al., bioRxiv - Neuroscience 2021

  Quote: ... BNP-saporin (BNP-sap) and blank-saporin were made by Advanced Targeting Systems. Pertussis toxin (PTX ...
• Stimulation of the muscarinic receptor M4 activates quiescent neural precursor cells and ameliorates medial septum cholinergic lesion-induced impairments in adult hippocampal neurogenesis

  Lidia I. Madrid, et al., bioRxiv - Neuroscience 2022

  Quote: ... Infusion of murine-p75 neurotrophin receptor (p75NTR)-Saporin (hereafter abbreviated as p75-Sap; 0.4 µg/µl; Advanced Targeting System) or control rabbit-IgG-Saporin (IgG-Sap ...
• Cholinergic basal forebrain degeneration due to obstructive sleep apnoea increases Alzheimer’s pathology in mice

  Lei Qian, et al., bioRxiv - Neuroscience 2020

  Quote: ... bilateral injections of urotensin II-saporin (UII-SAP; 0.07μg/μL per site – unless stated otherwise; generous gift from Advanced Targeting Systems) in the laterodorsal tegmental nucleus (A-P ...
• Rescuing the attentional performance of rats with cholinergic losses by the M1 positive allosteric modulator TAK-071

  Aaron Kucinski, et al., bioRxiv - Neuroscience 2019

  Quote: ... Basal forebrain cholinergic neurons situated in the nucleus basalis and substantia innominata were targeted with the immunotoxin 192 IgG-saporin (SAP; Advanced Targeting Systems) in aCSF (Tocris Bioscience ...
• Cholinergic interneurons in the dorsal striatum play an important role in the acquisition of duration memory

  Masahiko Nishioka, Toshimichi Hata, bioRxiv - Animal Behavior and Cognition 2023

  Quote: ... Each group of rats had either aCSF or anti-choline acetyltransferase (ChAT)-saporin (ChAT-SAP, IT-42, Advanced Targeting Systems, California, USA) infused into the bilateral DS using a gas-tight syringe (100 μL ...
• Light-controlled elimination of PD-L1+ cells

  Judith Jing Wen Wong, Pål Kristian Selbo, bioRxiv - Cancer Biology 2021

  Quote: The immunotoxin anti-human PD-L1-saporin (Anti-PD-L1-SAP, BETA-014) was generously provided by Advanced Targeting Systems (ATS, Carlsbad, CA, USA). The targeted toxin is a 295 kDa conjugate between a rabbit polyclonal antibody to human PD-L1 and the secondary conjugate streptavidin-saporin ...