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Citations for Toronto Research Chemical :
1 - 50 of 128 citations for 7H 1 2 3 Triazolo 4 5 d pyrimidin 7 one 3 6 dihydro since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Genetics 2024Quote: ... then 1-NM-PP1 (4-amino-1-tert-butyl-3-(1’-naphthylmethyl)pyrazolo[3-4-d]pyrimidine) (Toronto Research Chemicals, Inc.; no. A603003) was added to a final concentration of 15 μM ...
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bioRxiv - Neuroscience 2020Quote: ... and N-[(1R,2R)-1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3- (pyrrolidin-1-yl)propan 2-yl] nonanamide (GENZ-123346) was obtained from Toronto Research Chemicals (TRC G363450) and solubilized in DMSO ...
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bioRxiv - Physiology 2021Quote: ... 7α,12α-dihydroxycholest-4-en-3-one-d7) (Toronto Research Chemicals, Ontario, Canada) and homogenized in chloroform/methanol (4 ml ...
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bioRxiv - Biophysics 2023Quote: Equimolar mixture of 3-amino-2-fluorobenzotrifluoride (Combi-Blocks, Cat#QA-4188) and 2,6-dichloro-4-isocyanatopyridine (Toronto Research Chemicals, cat#159178-03-7) were stirred and heated in anhydrous Toluene at 85°C overnight ...
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bioRxiv - Cell Biology 2023Quote: Equimolar mixture of 3-amino-2-fluorobenzotrifluoride (Combi-Blocks, Cat#QA-4188) and 2,6-dichloro-4-isocyanatopyridine (Toronto Research Chemicals, cat#159178-03-7) were stirred and heated in anhydrous Toluene at 85°C overnight ...
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bioRxiv - Biochemistry 2023Quote: ... D-amino standards were generated by reacting the L-amino acid solution with 1-fluoro-2-4-dinitrophenyl-5-D-alanine amide (D-FDAA, Toronto Research Chemicals). These reaction products are enantiomers to the hypothetical D-amino acid and L-FDAA coupled products ...
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bioRxiv - Pathology 2020Quote: ... 4-methylumbelliferyl 6-sulfa-2-acetoamido-2-deoxy-b-D-glucopyranosidase (Toronto Research Chemicals, Cat. No. M335000, Ontario Canada), and 4-methylumbelliferyl N-acetyl b-D-glucosaminide (Sigma Aldrich ...
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bioRxiv - Microbiology 2020Quote: ... 3’-deoxy-3’-fluorothymidine (DFT, CAS number 25526-93-6) was obtained from Toronto Research Chemical, North York ...
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bioRxiv - Cell Biology 2022Quote: ... cells were grown in YES at 32°C to mid-log phase and treated with 4-amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-3]pyrimidine (3MB-PP1) (Toronto Research Chemical; A602960 or Cayman Chemical; 17860) at a final concentration of 15 µM for 30 min ...
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bioRxiv - Cancer Biology 2020Quote: ... D-ribose 5-phosphate (R5P, 30 μM), D/L-glyceraldehyde-3-phosphate (G3P, 30 μM), D-2-phosphoglycerate (2PG, 10 μM) from Toronto Research Chemicals, North York ...
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bioRxiv - Biophysics 2023Quote: ... 1-oxyl2,2,5,5-tetramethyl-3-pyrroline-3-methyl methanethiosulfonate (MTSL, Toronto Research Chemicals) and kept stirring at room temperature for 30 minutes ...
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bioRxiv - Pharmacology and Toxicology 2019Quote: ... 2-hydroxy-3-methylanthraquinone (13) and 2-hydroxy-1-methylanthraquinone (14) were obtained from Toronto Research Chemical, ON ...
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bioRxiv - Physiology 2021Quote: Calibration standards were prepared across the range 1 to 100 ng/ml in charcoal stripped plasma SP1070 (Golden West Biological) using authentic 7α-hydroxy-4-cholesten-3-one (obtained from Toronto Research Chemicals).
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bioRxiv - Cancer Biology 2023Quote: 3-methyl-2-oxovaleric acid sodium salt (KMV) (Toronto Research Chemical), 4-methyl-2-oxovaleric acid (KIC ...
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bioRxiv - Immunology 2022Quote: ... cells were activated with 30μM 5-amino-4-D-ribitylaminouracil dihydrochloride (5-ARU, Toronto Research Chemicals, Canada). IL-2 was added 72 hours after their activation in order to avoid non-MAIT cells growth ...
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bioRxiv - Plant Biology 2023Quote: ... approximately 0.08 to 0.1 g of frozen tissue ground in liquid nitrogen was extracted with 1 mL of cold acetonitrile: isopropanol: water (3:3:2, v/v/v) containing 10 nM of abscisic acid-d6 (Toronto Research Chemicals) and 10 nM salicylic acid-13C6 (Santa Cruz Biotechnology ...
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bioRxiv - Microbiology 2022Quote: ... and 5% bovine serum albumin) supplemented with 0.25 mM 2’-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid (MUNANA) sodium salt (Toronto Research Chemicals), was then added to each well ...
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The MPS1 kinase NTE region has helical propensity and preferred conformations towards the TPR domainbioRxiv - Biochemistry 2020Quote: ... MTS (1-acetyl-2,2,5,5-tetramethyl-3-pyrroline-3-methyl)-methanethiosulfonate) and MTSL were purchased from Toronto Research Chemicals.
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bioRxiv - Pharmacology and Toxicology 2021Quote: ... and 4-Hydroxy-4-(3-pyridyl)-butyric acid (HPBA) was purchased from Toronto Research Chemicals (TRC, Ontario, Canada). The metabolites hypoxanthine ...
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bioRxiv - Pharmacology and Toxicology 2022Quote: ... was used as the IS for 4-MU and 7-hydroxycoumarin β-D-glucuronide (Toronto Research Chemicals, Ontario, Canada) as the IS for 4-MUG ...
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bioRxiv - Biophysics 2021Quote: ... The cells expressing either BtuB WT or a cysteine variant were incubated with 15 µM of either 1-oxyl2,2,5,5-tetramethyl-3-pyrroline-3-methyl methanethiosulfonate (MTSL, Toronto Research Chemicals), 3-Maleimido-2,2,5,5-tetramethyl-1-pyrrolidinyloxy (M-PROXYL ...
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bioRxiv - Cell Biology 2020Quote: ... 2 mM 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR, Toronto Research Chemicals), or 500 ng/mL mouse recombinant Gremlin 1 (R&D Biosciences ...
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bioRxiv - Biophysics 2023Quote: Protein was spin-labeled using MTSL ((1-Acetoxy-2,2,5,5-tetramethyl-δ-3-pyrroline-3-methyl) Methanethiosulfonate) purchased from Toronto Research Chemicals. Prior to labeling ...
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bioRxiv - Biophysics 2019Quote: ... and RLC was incubated at 4°C for 1hr in 5-fold molar excess of bifunctional 3,4-Bis-(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy spin label (BSL; Toronto Research Chemicals). The covalent disulfide double bond between BSL and the 𝛼-helix backbone produces bifunctional stereospecific attachment in this labeling conditions (Fig ...
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bioRxiv - Genetics 2022Quote: ... 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) was purchased from Toronto Research Chemicals. Methanol was purchased from Sigma ...
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bioRxiv - Immunology 2022Quote: Homotypic or heterotypic tumor spheroids were treated with a MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-ARU, Toronto Research Chemicals, Canada), diluted in RPMI media ...
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bioRxiv - Cell Biology 2020Quote: ... cells grown on a 6cm tissue culture plate were untreated or treated with 1mM 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) (Toronto Research Chemicals) in presence of 5.5mM or 25mM glucose ...
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Large-scale conformational changes of FhaC provide insights into the two-partner secretion mechanismbioRxiv - Biophysics 2022Quote: ... The FhaC-containing fractions were mixed with a 10-fold molar excess (1-oxyl-2,2,5,5-tetramethyl-Δ3-pyrroline-3-methyl) methanethiosulfonate (MTSL) or its diamagnetic analogue (1-Acetoxy-2,2,5,5-tetramethyl-δ-3- pyrroline-3-methyl) methanethiosulfonate (Toronto Research Chemicals, North York, ON, Canada) at 15°C with gentle agitation for 16 hours ...
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bioRxiv - Biophysics 2020Quote: ... Protein was then labelled overnight at 4 °C with (1-oxyl-2,2,5,5-tetramethylpyrrolidin-3- yl)methylthiosulfonate spin label (MTSL, 20x excess) (Toronto Research Chemicals Inc., North York, Ontario, Canada) with gentle agitation ...
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bioRxiv - Microbiology 2021Quote: ... and oseltamivir carboxylate (Toronto Research Chemicals, Lot 3-SKC-52-1, Purity 98%) with a qualified LC MS/MS assay ...
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bioRxiv - Cell Biology 2021Quote: ... the 3-MBPP1 inhibitor (A602960, Toronto Research Chemicals, Inc.) was dissolved in DMSO at stock concentrations of 10 or 0.4 mM and added to liquid cultures at a final concentration of 1 or 0.05 μM ...
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bioRxiv - Cell Biology 2023Quote: Adult mice (2-3 months) were injected intraperitoneally for 5 consecutive days with 125 mg/kg of tamoxifen dissolved in corn oil (Toronto Research Chemicals, T006000 ...
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bioRxiv - Plant Biology 2021Quote: ... Cyanidin-3-O-xyloside was obtained from Toronto Research Chemicals Inc ...
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bioRxiv - Physiology 2021Quote: ... and 3-hydroxydodecanedioic (97%) were obtained from Toronto Research Chemical Inc ...
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bioRxiv - Neuroscience 2023Quote: ... A mixture of tamoxifen (3 mg, Toronto Research Chemicals, T006000), progesterone (MilliporeSigma ...
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bioRxiv - Cell Biology 2021Quote: ... used an analogue-sensitive version of the Cyclin-DK Cdc2 (cdc2-asM17, (Aoi et al, 2014)) which can be inhibited by 2 µM of 3-Br-PP1 (A602985, Toronto Research Chemicals). After 3 hours in the presence of the drug at 28°C in rich medium ...
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bioRxiv - Cell Biology 2023Quote: ... Cells were arrested in late G2 by 3h incubation in the presence of 3-Br-PP1 at 2 µM final concentration (#A602985, Toronto Research Chemicals). Cells were released into synchronous mitosis by filtration and 3 washes with prewarmed liquid growing medium ...
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bioRxiv - Cell Biology 2021Quote: ... the ATP-analogues 1-NM-PP1 and and 3-MB-PP1 were obtained from Toronto Research Chemicals (A603003; A602960).
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bioRxiv - Biophysics 2020Quote: ... Protein after PD-10 was labeled overnight at 4°C by immediately mixing with a 10-fold molar excess of the spin label (1-oxyl-2,2,5,5-tetramethylpyrroline-3-methyl) methanethiosulfonate (MTSL; Toronto Research Chemicals), resulting in spin labelled tau at designated site ...
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bioRxiv - Biochemistry 2023Quote: ... purified CorA was reacted with a 10-fold molar excess of 1-Oxyl-2,2,5,5-tetramethylpyrroline-3-methyl)methanethiosulfonate (MTSL; Toronto Research Chemicals) for 30 min on ice ...
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bioRxiv - Molecular Biology 2023Quote: All VOCs were purchased from Sigma-Aldrich (except for (5Z)-octa-1,5-dien-3-ol from Toronto Research Chemicals) in the highest available purity ...
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bioRxiv - Pathology 2020Quote: ... 4-methylumbelliferyl a-D-manopyranoside (Toronto Research Chemicals, Cat. No. M334745, Ontario Canada), 4-methylumbelliferyl 6-sulfa-2-acetoamido-2-deoxy-b-D-glucopyranosidase (Toronto Research Chemicals ...
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bioRxiv - Molecular Biology 2024Quote: ... 5-(hydroxymethyl)-2′-deoxycytidine-2H3 (#H946632, Toronto Research Chemicals). MS2 data for 5hmC ...
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bioRxiv - Biochemistry 2023Quote: ... crude phosphorothioate-modified DNA oligonucleotide was mixed with an acetonitrile/water (50%/50% by volume) solution containing a R5 precursor [3-Iodomethyl-1-oxyl-2,2,5,5-tetramethylpyrroline (Toronto Research Chemicals, cat. no. I709500)] (60-100mM ...
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bioRxiv - Cell Biology 2022Quote: ... cells were treated with 5μM ATP analog 3-BrB-PP1 (Toronto Research Chemicals; A602985) during 18 °C incubation for 1.5 hr to inactivate Sty1 kinase activity before being collected ...
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bioRxiv - Molecular Biology 2023Quote: ... 5-(hydroxymethyl)-2′-deoxycytidine-2H3 (Cat# H946632, Toronto Research Chemicals). MS2 data for 5hmC ...
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bioRxiv - Microbiology 2021Quote: ... A 200 μL aliquot of plasma was then quickly pipetted from each sample and transferred into a separate 2 mL microcentrifuge tube containing 800 μL of ice cold 15 ng/mL oseltamivir-d3 carboxylate (Toronto Research Chemicals, Lot 14-SBK-47-3, Purity 97%) in methanol ...
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bioRxiv - Pharmacology and Toxicology 2023Quote: ... 7-hydroxycoumarin-d5-sulfate and 7-hydroxycoumarin-13C6-glucuronide were purchased from Toronto Research Chemicals. 4-hydroxymephenytoin-d3 was purchased from MuseChem ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... 7-ketodeoxycholate and 7-ketolithocholic acid were purchased from Toronto Research Chemicals (North York, ON, Canada). Formic acid (99+% ...
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bioRxiv - Genomics 2021Quote: ... were purchased from Sigma- Aldrich (Oakville, ON) and PFDS was purchased from Toronto Research Chemicals (95% purity CAS 335-77-3 Toronto, ON). Chemicals were dissolved in dimethylsulfoxide (DMSO ...