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1 - 50 of 253 citations for 6 Hydrazinophenanthridine since 2019

• A Multi-Omics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations

  Gabriel Sturm, et al., bioRxiv - Cell Biology 2022

  Quote: ... interleukin 6 (IL-6, Abcam#ab229434) and growth differentiation factor 15 (GDF15 ...
• Afucosylated maternal anti-dengue IgGs are a biomarker for susceptibility to dengue disease in their infants

  Natalie K. Thulin, et al., bioRxiv - Immunology 2019

  Quote: ... INCA-6 (Abcam; ab145864), 11R-VIVIT (Thermo Fisher ...
• Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes

  Jonathan D Teo, et al., bioRxiv - Neuroscience 2022

  Quote: ... TMEM119 (106-6, Abcam) and anti-CD86 (GL-1 ...
• Harnessing PROTAC technology to combat stress hormone receptor activation

  Mahshid Gazorpak, et al., bioRxiv - Molecular Biology 2023

  Quote: ... IL-6 (Abcam ab259341), H3 (Abcam ab1791 ...
• Maresin-2 Fine-tunes ULK1 O-GlcNAcylation to Improve Post Myocardial Infarction Remodeling

  Jingjing Zhang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... (IL-6, Abcam, ab222503), interlrukin-10 (IL-10 ...
• DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION

  Mingzhuo Zhang, et al., bioRxiv - Physiology 2024

  Quote: ... 6 (PSMC6) (Abcam, ab22639), Lysosomal membrane protein 1 (LAMP1 ...
• Homeostasis of the intervertebral disc requires regulation of STAT3 signaling by the adhesion G-protein coupled receptor ADGRG6

  Zhaoyang Liu, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-IL-6 (Abcam, ab6672), and anti-phospho-STAT3 (Cell Signaling ...
• MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

  Xintao Qiu, et al., bioRxiv - Genomics 2021

  Quote: ... FOXA1 (6 μg, #ab23738, Abcam), RNA Pol II (4 μg ...
• Bid as a novel interacting partner of IRE1 differentially regulating its RNAse activity

  Samirul Bashir, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-ATF-6 antibody (Abcam), anti-Grp78 antibody (Cell Signaling Technologies) ...
• Disruption of the CSF-1-CSF-1R axis alters cerebellar microglia and is associated with motor and social interaction defects

  Veronika Kana, et al., bioRxiv - Neuroscience 2019

  Quote: ... Tmem119 (clone 106-6, Abcam), and either DAPI or Propium Iodide viability dyes (all from eBioscience if not indicated otherwise) ...
• NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity

  Kelley Ingram, et al., bioRxiv - Cancer Biology 2021

  Quote: ... NKX2-1 (EPR8190-6, Abcam), and GAPDH and subsequently with DyLight fluorochrome-conjugated secondary antibodies (Thermo Fisher Scientific) ...
• Intragastric administration of low-dose rotenone post-colitis exacerbates damage to the nigrostriatal dopaminergic system in Parkinson’s disease: The pace accelerates even more

  Nishant Sharma, et al., bioRxiv - Neuroscience 2022

  Quote: ... and IL-6 (Abcam, 46100) according to manufacturer’s protocol.
• SPTF-3/SP1 orchestrates mitochondrial biogenesis upon ribosomal stress and acute starvation

  Johannes CW Hemerling, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HSP-6 (Grp70, Abcam, #82591), HSP-60 (ATCC) ...
• NRF2 activation in the heart induces glucose metabolic reprogramming and mediates cardioprotection via upregulation of the pentose phosphate pathway

  Anna Zoccarato, et al., bioRxiv - Physiology 2023

  Quote: ... 6-phosphogluconate dehydrogenase (Abcam, ab129199), transaldolase 1 (ThermoFisher Scientific ...
• Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease

  Bo Am Seo, et al., bioRxiv - Neuroscience 2024

  Quote: ... pH 6 (10X, #ab64214, Abcam). Subsequently ...
• Induction of exaggerated cytokine production in human peripheral blood mononuclear cells by a recombinant SARS-CoV-2 spike glycoprotein S1 and its inhibition by dexamethasone

  Olumayokun A Olajide, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Levels of IL-6 in supernatants were determined using human IL-6 ELISA kit (Abcam). The range for IL-6 detection was 7.8-500 pg/mL ...
• Cardiac Cell-Derived Matrices Impart Age-Specific Functional Properties to Human Cardiomyocytes

  M. A. Kauss, et al., bioRxiv - Cell Biology 2020

  Quote: ... Col 6 (Abcam ab6588, 1:500), Hoescht 33342 (ThermoFisher 62249 ...
• Fibrin, Bone Marrow Cells and macrophages interactively modulate cardiomyoblast fate

  Inês Borrego, et al., bioRxiv - Physiology 2022

  Quote: ... IL-6 (ab119548; Abcam, United Kingdom), TNF-alfa (ab46070 ...
• The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae

  Natalia I. Reim, et al., bioRxiv - Genomics 2020

  Quote: ... 6 μg anti-H3K36me2 (Abcam, ab9049), 6 μg anti-H3K4me3 (Abcam ...
• The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae

  Natalia I. Reim, et al., bioRxiv - Genomics 2020

  Quote: ... 6 μg anti-H3K4me3 (Abcam, ab8580), 10 μg anti-Ser5-P (Active Motif ...
• The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae

  Natalia I. Reim, et al., bioRxiv - Genomics 2020

  Quote: ... 6 μg anti-H3K36me3 (Abcam, ab9050), 6 μg anti-H3K36me2 (Abcam ...
• Topoisomerase VI participates in an insulator-like function that prevents H3K9me2 spreading into euchromatic islands

  Louis-Valentin Méteignier, et al., bioRxiv - Plant Biology 2019

  Quote: ... H3K9me2 (Abcam ab1220, lot: GR244373-6), H3 (Abcam ab1791 ...
• Single-cell analysis of chromatin silencing programs in development and tumor progression

  Steven J. Wu, et al., bioRxiv - Genomics 2020

  Quote: ... OCT4 (Abcam, ab109183, lot gr120970-6), and H3K4me2 (Upstate 07–030 ...
• High CXCL6 drives matrix expression and correlate with markers of poor outcome in IPF

  Harinath Bahudhanapati, et al., bioRxiv - Cell Biology 2021

  Quote: ... Anti-CXCL5/6 antibody (ab198505; Abcam), Mouse anti-β-actin (sc-47778 ...
• Proresolving mediators LXB₄ and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears

  Stephanie G Dakin, et al., bioRxiv - Cell Biology 2019

  Quote: ... and anti-IL-6 (Abcam ab9324) in PBS containing 5% goat serum in Saponin for 3 hrs at room temperature ...
• Transneuronal delivery of designer-cytokine enables functional recovery after complete spinal cord injury

  Marco Leibinger, et al., bioRxiv - Neuroscience 2019

  Quote: ... IL-6 (1:1000; Abcam; RRID:AB_2127460), pAKT-Thr308 (1:500 ...
• Transneuronal delivery of designer-cytokine enables functional recovery after complete spinal cord injury

  Marco Leibinger, et al., bioRxiv - Neuroscience 2019

  Quote: ... IL-6 (1:500; Abcam; RRID:AB_2127460) GFAP (1:50 ...
• Spatial organisation and homeostasis of epithelial lineages at the gastroesophageal junction is regulated by the divergent Wnt mucosal microenvironment

  Naveen Kumar, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mouse anti-cytokeratin 6 (Abcam, ab18586), donkey anti-rabbit–Cy3 (Jackson Immuno Research ...
• Combined KRAS^G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS^G12C-driven cancers by addressing intrinsic and acquired resistance

  Venu Thatikonda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... DUSP-6 (Abcam #ab76310; 1:1000), cleaved PARP (Asp214 ...
• Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling

  Kaitlin R. Carroll, et al., bioRxiv - Immunology 2023

  Quote: ... and TMEM119 (Clone 106-6, Abcam) indicated a microglial purity of greater than 95%.
• Early inflammatory response mediated by Angiotensin II in cardiac arteries of normotensive mice

  Thais Cristina de Souza Oliveira, et al., bioRxiv - Physiology 2023

  Quote: ... and IL-6 (abcam®6672), tumor necrosis factor-alpha TNF-α (abcam®6671) ...
• SOX4-SMARCA4 complex promotes glycolysis-dependent TNBC cell growth through transcriptional regulation of Hexokinase 2

  Pooja Khanna, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and glucose-6-phosphate (Abcam AB83426) levels were measured using colorimetric assays following SOX4 ...
• Conditional deletion of CEACAM1 causes hepatic stellate cell activation

  Harrison T. Muturi, et al., bioRxiv - Physiology 2024

  Quote: ... interleukin-6 (ELISA Kit, ab222503, Abcam) and TNFα (ELISA Kit ...
• Conditional deletion of CEACAM1 causes hepatic stellate cell activation

  Harrison T. Muturi, et al., bioRxiv - Physiology 2024

  Quote: ... interleukin-6 (ELISA-ab 178018, Abcam) and TNFα (ELISA-ab181421 ...
• Fate tracing reveals differences between Reelin⁺ HSCs and Desmin⁺ HSCs in activation, migration, and proliferation activities

  Ning Chen, et al., bioRxiv - Pathology 2022

  Quote: ... 6-diamidino-2-phenylindole (DAPI) (Abcam, ab104139). Images were acquired with a laser scanning confocal microscope (Carl Zeiss Microscopy ...
• Effect of compound Tinglizi Decoction on non-classical pathway of pyroptosis in rats with chronic obstructive pulmonary disease related pulmonary hypertension

  Qizhi Wang, Min Liu, Yu Liu, Zhengping Bai, bioRxiv - Cell Biology 2022

  Quote: ... IL-6 (Abcam, UK, Article No.: ab233706); IL-1 β ( British Abcam ...
• A novel hybrid protein promotes Aβ clearance and reduces inflammatory response through MerTK

  Lorena P. Samentar, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-IL-6 (Abcam Cat# ab6672, RRID:AB_2127460) and anti-IL-10 (Bioss #bs-069812 ...
• Nanoscopical analysis reveals an orderly arrangement of the presynaptic scaffold protein Bassoon at the Golgi-apparatus

  Tina Ghelani, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Syntaxin 6 (1:300 Abcam), chicken anti-GFP (1 ...
• QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1-PPARγ-PGC-1α axis

  Rui Liu, et al., bioRxiv - Neuroscience 2020

  Quote: ... QKI 6 (1:2000; Abcam, Cambridge, UK), PGC-1 α (1:1000 ...
• RORβ modulates a gene program that is protective against articular cartilage damage

  Mi Ra Chang, Patrick R. Griffin, bioRxiv - Cell Biology 2022

  Quote: ... Anti-aggrecan Ab (6-B-4, abcam) was used for primary antibody and FITC-anti mouse Ab was used for secondary antibody ...
• Transneuronal delivery of designer-cytokine enables functional recovery after complete spinal cord injury

  Marco Leibinger, et al., bioRxiv - Neuroscience 2019

  Quote: ... and IL-6 (1:500; Abcam; RRID:AB_2127460). Stained axons were photographed using a confocal microscope (630 x ...
• Chaperone-mediated Autophagy Deficiency Reprograms Cancer Metabolism Via TGFβ Signaling to drive Mesenchymal Tumor Growth

  Xun Zhou, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TGFβR2 (Abcam, ab184948; Santa Cruz, E-6), TGFβR1 (Abcam ...
• Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive

  Daniel R. Hochbaum, et al., bioRxiv - Neuroscience 2023

  Quote: ... 6% normal goat serum (NGS, Abcam ab7481) in PBS for 2 hours at RT ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... 4’,6-Diamidino-2-phenylindole (DAPI, Abcam) was used for nuclear staining ...
• Requirements for establishment and epigenetic stability of mammalian heterochromatin

  Antonis Tatarakis, Harleen Saini, Danesh Moazed, bioRxiv - Developmental Biology 2023

  Quote: ... 6 μg of anti-DHX9 (Abcam 26271) with protein A ...
• Quantitative Three-dimensional Label-free Digital Holographic Imaging of Cardiomyocyte Size, Ploidy, and Cell Division

  Sangsoon Park, et al., bioRxiv - Cell Biology 2023

  Quote: ... 6-diamidino-2-phenylindole (DAPI, AB2285492, Abcam) in order to stain nuclei prior to imaging on a Keyence BZ-X810 or Nikon TE300 inverted microscopes.
• Noradrenergic signaling controls Alzheimer’s disease pathology via activation of microglial β2 adrenergic receptors

  L. Le, et al., bioRxiv - Neuroscience 2023

  Quote: ... & TMEM119-PE (106-6, 1:500, Abcam). The latter two cell surface molecules are considered homeostatic microglial markers 26,27 ...
• Sex differences and risk factors for bleeding in Alagille syndrome

  Simona Hankeova, et al., bioRxiv - Developmental Biology 2021

  Quote: Fibrinogen was measured in P10 serum (6 Jag1+/+ and 6 Jag1Ndr/Ndr mice) using a commercial kit (cat. #ab213478, Abcam), according to manufacturer’s instructions ...
• Topoisomerase VI participates in an insulator-like function that prevents H3K9me2 spreading into euchromatic islands

  Louis-Valentin Méteignier, et al., bioRxiv - Plant Biology 2019

  Quote: ... or anti-H3K9me2 (Abcam ab1220, lot: GR244373-6) antibodies were used at 1:100 ...
• Stabilization of α-synuclein oligomers using formaldehyde

  Harm Ruesink, et al., bioRxiv - Neuroscience 2019

  Quote: ... and MJFR-14-6-4-2 (MJF14) (abcam, catalog no ...