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1 - 50 of 10000+ citations for 6 Chloro 9 2 C methyl β D riboFuranosyl 9H purine since 2019

• A CD24+CD271+ melanoma cancer stem cell generates a diffuse hierarchy of attributes that promote metastasis and therapeutic resistance

  Olivia Knowles, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2 ng/ml TGF-β (R&D Systems) was added ...
• Selective modulation of cell surface proteins during vaccinia infection: implications for immune evasion strategies

  Delphine M Depierreux, et al., bioRxiv - Microbiology 2021

  Quote: ... ULBP-2/5/6 (65903, R&D systems), Plexin-B1 (rea728 ...
• Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation

  Rachel E. Heap, et al., bioRxiv - Immunology 2020

  Quote: ... IL-6 and IFN-β (DuoSet mouse ELISA kits from R&D Systems) were performed according to manufacturer’s instruction.
• Early-life microbial intervention reduces colitis risk promoted by antibiotic-induced gut dysbiosis

  Jun Miyoshi, et al., bioRxiv - Microbiology 2020

  Quote: ... and 2 ng/ml recombinant mouse TGF-β (R&D Systems). Cells were incubated with bacterial lysates at 37°C for 72 hours ...
• Bortezomib inhibits lung fibrosis and fibroblast activation without proteasome inhibition

  Loka Raghu Kumar Penke, et al., bioRxiv - Molecular Biology 2021

  Quote: Recombinant human transforming growth factor-β (TGF-β) and fibroblast growth factor-2 FGF-2 were purchased from R&D Systems. BTZ ...
• Cutaneous Wounds in Mice Lacking Tumor Necrosis Factor-stimulated Gene-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response

  Sajina Shakya, et al., bioRxiv - Physiology 2020

  Quote: ... with 2 µg of recombinant human TSG-6 (rTSG-6, R&D Systems, Minneapolis, MN) in 100 µl PBS (or with PBS alone ...
• TIMP-1 attenuates the development of inflammatory pain through MMP-dependent and receptor-mediated cell signaling mechanisms

  B.E. Knight, et al., bioRxiv - Neuroscience 2019

  Quote: ... MMP-9 (R&D Systems; Minneapolis, MN), IL-6 (Invitrogen Carlsbad ...
• Medroxyprogesterone reverses tolerable dose metformin-induced inhibition of invasion via matrix metallopeptidase-9 and transforming growth factor-β1 in KLE endometrial cancer cells

  Dong Hoon Suh, et al., bioRxiv - Cancer Biology 2019

  Quote: ... the secretion levels of Matrix metallopeptidase (MMP)-2 and -9 (R&D system, MN, USA) and transforming growth factor (TGF)-β1 (R&D system ...
• Jagged-1 regulates Foxp3 expression and cytokine production in CD4⁺ T cells

  Soichiro Kimura, et al., bioRxiv - Immunology 2019

  Quote: ... 10 ng/mL of rmIL-2 and 2 ng/mL of rhTGF-β (R&D systems) were added to complete RPMI (10% FCS ...
• Legionella pneumophila inhibits type I interferon signaling to avoid cell-intrinsic host cell defense.

  Charles N.S. Allen, et al., bioRxiv - Microbiology 2023

  Quote: ... IFN-β (R&D Systems) or IFN-γ (R&D Systems ...
• Early-life microbial intervention reduces colitis risk promoted by antibiotic-induced gut dysbiosis

  Jun Miyoshi, et al., bioRxiv - Microbiology 2020

  Quote: ... and 2 ng/ml recombinant mouse TGF-β (R&D Systems, Minneapolis, MN).
• Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs

  Huiyun Lyu, et al., bioRxiv - Immunology 2023

  Quote: Recombinant Human IL-2 and human TGF-β were from R&D systems. Anti-mouse CD3 and biotin-anti-CD3 (145-2C11 ...
• Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells

  Rui Santalla Méndez, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cell lysates were then incubated with 2 μg of anti-galectin-9 (AF2545, R&D systems) or isotype control under rotation ...
• Intracellular Galectin-9 controls dendritic cell function by maintaining plasma membrane rigidity

  Laia Querol Cano, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti-Galectin-9 (AF2045, R&D systems) at 20 μg/ml ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 9 ng/ml Activin A (R&D Systems), 5 ng/ml FGF-2 (R&D Systems ...
• LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

  Ningbo Zheng, et al., bioRxiv - Immunology 2024

  Quote: ... and mouse IL-9 (#DY409, R&D Systems).
• LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation

  Ahmed M. Fahmy, et al., bioRxiv - Immunology 2023

  Quote: Collected supernatants were assayed for IL-6 and IFN-β using mouse DuoSet kits (R&D Systems). Samples were diluted in PBS and incubated in a 96-well plate pre-coated with either IL-6 or IFN-β capture antibodies for 2h at room temperature ...
• Rac1/ROCK-driven membrane dynamics promote Natural Killer cell cytotoxicity via necroptosis

  Yanting Zhu, Jun Xie, Jue Shi, bioRxiv - Cell Biology 2020

  Quote: ... PE anti-human ULBP-2/5/6 (Clone 165903, R&D Systems), FITC Mouse IgG1 κ Isotype Control (Clone MOPC-21 ...
• Multi-tier mechanics control stromal adaptations in swelling lymph nodes

  Frank P. Assen, et al., bioRxiv - Immunology 2021

  Quote: ... α- PDGFR-β (R&D Systems), α-YAP/TAZ (D24E4 ...
• Inhibition of the αv integrin-TGF-β axis improves natural killer cell function against glioblastoma stem cells

  Hila Shaim, et al., bioRxiv - Immunology 2020

  Quote: ... supernatants were collected and secretion of TGF β and MMP2/3/9 was assessed in the supernatant by TGFβ1 ELISA kit (R&D systems) or MMP2/3/9 luminex kit (eBiosciences ...
• Precise Therapeutic Targeting of Distinct NRXN1^+/- Mutations

  Michael B. Fernando, et al., bioRxiv - Neuroscience 2023

  Quote: ... Ara-C and 2% low-hemoglobin FBS (R&D systems #S11510). iGLUT neurons were distributed among wells (500-750k cells per 24wp or 0.75-1.5E6 cell per 12wp ...
• Imbalance of Neuregulin1-ErbB2/3 signaling underlies altered myelin homeostasis in models of Charcot-Marie-Tooth disease type 4H

  Lara El-Bazzal, et al., bioRxiv - Neuroscience 2022

  Quote: ... and 2 ng/ml recombinant human NRG1-β 1 (#396-HB, R&D Systems, USA) as described in Poitelon et al ...
• Galectin-9 signaling drives breast cancer invasion through matrix

  Dharma Pally, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Galectin-9 primary antibody (R&D systems, AF-2045) was added to sections at 1 μg/mL dilution and incubated overnight at 4 °C ...
• Soft, dynamic hydrogel confinement improves kidney organoid lumen morphology and reduces epithelial–mesenchymal transition in culture

  Floor A.A. Ruiter, et al., bioRxiv - Bioengineering 2021

  Quote: ... and FGF-9 (200 ng·ml-1, R&D Systems). By day 7 ...
• Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2

  Ronja Wieboldt, et al., bioRxiv - Immunology 2023

  Quote: ... Siglec-9 blocking antibody (Clone 191240, R&D Systems) was added at a final concentration of 10 µg/mL ...
• Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2

  Ronja Wieboldt, et al., bioRxiv - Immunology 2023

  Quote: ... Siglec-9 blocking antibody (Clone 191240, R&D Systems) was added at a final concentration of 10 µg/mL ...
• RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects: Therapeutic implications

  Kiwon Lee, et al., bioRxiv - Cancer Biology 2022

  Quote: ... human cytokines (1 ng/ml stem cell factor, 100 ng/ml thrombopoietin, 13.5 ng/ml interleukin 9, 10 ng/ml interleukin 6; all cytokines from R&D Systems), and 1XPenicillin-Streptomycin (Gibco ...
• Precision Targeting of the Plasminogen Activator Inhibitor-1 Mechanism Increases Efficacy of Fibrinolytic Therapy in Empyema

  Galina Florova, et al., bioRxiv - Biochemistry 2020

  Quote: ... TGF-β (DY240-05, R&D Systems), IL-6 (DY7984 ...
• Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection

  Mack B. Reynolds, et al., bioRxiv - Immunology 2024

  Quote: ... IL-β (DY 401, R&D Systems), and IFN-β (DY 8234-05 ...
• 3D bioprinting of an implantable xeno-free vascularized human skin graft

  Tania Baltazar, et al., bioRxiv - Bioengineering 2022

  Quote: ... α6 (MAB13501; R&D systems), α3 (MAB1345 ...
• Aberrant activation of Wnt/β-Catenin signaling pathway drives the expression of poor prognosis-associated microRNAs in adrenocortical cancer with a major impact on miR-139-5p and its host gene PDE2A

  Justine Cristante, et al., bioRxiv - Cancer Biology 2023

  Quote: The blots were probed overnight at 4°C with monoclonal mouse anti-β-Catenin (2 µg/mL in Bovine Serum Albumin 3%, R&D Systems, Minneapolis, USA, #MAB1329), monoclonal rabbit anti-NDRG4 (1:1000 ...
• Low-dose cytokine immunotherapy of solid cancers enabled by phagocytic-competent protein co-crystals

  Michael H Jones, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 3 and 6 days and subsequently tested by IL-2 ELISA (R&D Systems) according to the manufacturer’s protocol.
• DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

  Geng Li, et al., bioRxiv - Microbiology 2020

  Quote: ... Recombinant human MMP-9 protein and Recombinant mice MMP-9 protein were purchased from R&D systems. Commercialized DENV2-NS1 protein were purchased from Native Antigen ...
• Intracellular Galectin-9 controls dendritic cell function by maintaining plasma membrane rigidity

  Laia Querol Cano, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti-Galectin-9 (AF2045, R&D systems, Minneapolis, Minnesota) at 1:1000 (v/v ...
• IgG-aggregates rapidly up-regulate FcgRI expression at the surface of human neutrophils in a FcgRII-dependent fashion: A crucial role for FcgRI in the generation of reactive oxygen species

  Sandrine Huot, et al., bioRxiv - Immunology 2020

  Quote: ... MMP-9 Duoset ELISA was obtained from R&D Systems, Inc ...
• DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

  Mihaela Peycheva, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and 1 ng/mL transforming growth factor β (TGF-β; R&D Systems), as described (43) ...
• SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species

  Dhiraj Kumar Singh, et al., bioRxiv - Immunology 2020

  Quote: ... Antihuman ACE-2 (R&D Systems, USA, 1:50, 2h at 37°C) was used for identification of ACE-2 ...
• Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9)

  Tatjana De Vos, et al., bioRxiv - Immunology 2022

  Quote: ... The functionalized tips were then dipped in different hIL-9 or mIL-9 (both from R&D systems) concentrations ...
• Human Rotavirus Diarrhea Is Associated with Altered Trafficking and Expression of Apical Membrane Transport Proteins

  Nicholas C. Zachos, et al., bioRxiv - Cell Biology 2019

  Quote: ... and β-catenin were from R&D Systems. Mouse monoclonal antibodies to ...
• The impact of Staphylococcus aureus cell wall glycosylation on langerin recognition and Langerhans cell activation

  A Hendriks, et al., bioRxiv - Microbiology 2020

  Quote: ... 10 ng/ml TGF-β (R&D systems) and 2.5 ng/ml TNF-α (R&D systems ...
• Stromal inflammation is a targetable driver of hematopoietic aging

  Evgenia V. Verovskaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 90x-diluted (TGF-β; R&D Systems) samples were prepared according to the manufacturer’s instructions and analyzed on a Synergy 2 plate reader (Biotek).
• Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses

  Jihyung Lee, et al., bioRxiv - Immunology 2019

  Quote: ... TGF-β (10 ng/ml, R&D systems) and TNF-α (2.5 ng/ml ...
• Fam72a controls the balance between error-prone and error-free DNA repair during antibody diversification

  Mélanie Rogier, et al., bioRxiv - Immunology 2020

  Quote: ... TGF-β (3 ng/ml, R&D Systems) and Retinoic Acid (RA ...
• Transcriptomic profiling implicates PAF1 in both active and repressive immune regulatory networks

  Matthew W. Kenaston, et al., bioRxiv - Molecular Biology 2022

  Quote: ... IFN-β (50 U/mL, R&D Systems), and TNF-α (100 ng/mL ...
• An AlphaFold2 map of the 53BP1 pathway identifies a direct SHLD3-RIF1 interaction critical for DNA repair activity

  Chérine Sifri, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1 ng/ml TGF-β (R&D Systems), and 10 ng/mL mIL-4 (R&D Systems) ...
• Overexpression of Alpha-1 Antitrypsin Increases the Proliferation of Mesenchymal Stem Cells by Upregulation of Cyclin D1 and is Independent of the Wnt Signaling Pathway

  Bryan Wolf, et al., bioRxiv - Cell Biology 2023

  Quote: ... rat anti-GSK3 β (R&D Systems, MAB2506), rabbit p-GSK3 β (Cell Signaling ...
• Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities

  Kathleen Pestal, et al., bioRxiv - Immunology 2024

  Quote: ... and 2ng/mL TGF-β (R&D Systems). On day 4 ...
• Precision Targeting of the Plasminogen Activator Inhibitor-1 Mechanism Increases Efficacy of Fibrinolytic Therapy in Empyema

  Galina Florova, et al., bioRxiv - Biochemistry 2020

  Quote: ... IL-6 (DY7984, R&D Systems), IL8 (ELL-IL8-1 ...
• Dissecting the respective roles of microbiota and host genetics in the susceptibility of Card9^-/- mice to colitis

  C. Danne, et al., bioRxiv - Genetics 2023

  Quote: ... and IL-6 (R&D Systems). Normalization to the dry weight of each colonic explant was done.
• Electrical stimulation of the dorsal motor nucleus of the vagus regulates inflammation without affecting the heart rate

  Aidan Falvey, et al., bioRxiv - Physiology 2023

  Quote: ... IL-6 (R&D Systems DY406); and IL-10 (R&D Systems DY417 and Luminex) ...