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8301 - 8350 of 10000+ citations since 2019

• ETAS®50 Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

  Ken Shirato, Jun Takanari, Takako Kizaki, bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... and Quantikine Mouse IL-1β ELISA Kit (R&D Systems), as described previously [14 ...
• Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats

  Alice Servonnet, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... SKF38393 hydrobromide and SCH39166 hydrobromide (R&D Systems, Minneapolis, MN) were dissolved in 0.9 % saline ...
• Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats

  Alice Servonnet, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... GBR12783 dihydrochloride (R&D Systems) was dissolved in DMSO ...
• Activin B Promotes the Initiation and Progression of Liver Fibrosis

  Yan Wang, et al., bioRxiv - Pathology 2021

  Quote: ... or TGFβ1 (R&D System, Minneapolis, MN) for six hours ...
• The Lack of Nrf2 Causes Hepatocyte Dedifferentiation and Reduced Albumin Production in an Experimental Extrahepatic Cholestasis Model

  Guo-Ying Wang, et al., bioRxiv - Pathology 2021

  Quote: ... DMBT1 (AF5195; R&D Systems), phosphorylated yes-associated protein 1 (p-YAP ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Foxp3 (1:200; R&D Systems, MAB8214). After washing ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PRSS2 activity were determined with 21.5 μM Mca-RPKPVE-Nval-WRK(Dnp)-NH2 Fluorogenic MMP Substrate (R&D Systems) (final concentration ...
• Interaction of micropatterned topographical and biochemical cues to direct neurite growth from spiral ganglion neurons

  Kristy Truong, et al., bioRxiv - Bioengineering 2021

  Quote: ... and brain derived neurotrophic factor (50 ng/ml, R&D Systems) to support neuronal survival (Hansen et al ...
• Interaction of micropatterned topographical and biochemical cues to direct neurite growth from spiral ganglion neurons

  Kristy Truong, et al., bioRxiv - Bioengineering 2021

  Quote: ... or EphA4-Fc (10 μg/ml, R&D Systems). The peptide-‘inked’ stamps were pressed onto a smooth polymer ...
• SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

  Amanda Jack, et al., bioRxiv - Biophysics 2021

  Quote: ... supplemented with 10% FBS (R&D Systems), 1X GlutaMAX (Gibco) ...
• Fatty acid binding proteins shape the cellular response to activation of the glucocorticoid receptor

  Bonan Liu, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... FABP3 (R&D Systems MAB1678; rabbit, 1:200), FABP4 (Abcam AB92501 ...
• CXCL17 is an endogenous inhibitor of CXCR4 via a novel mechanism of action

  Carl W. White, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Unlabeled chemokine ligands were purchased from Preprotech (USA) except for 24Leu-CXCL17 which was purchased from R&D Systems and 22Ser-CXCL17 which was purchased from Sapphire Bioscience (Australia) ...
• Engineering the Immune Adaptor Protein STING as a Biologic

  Xin Sun, et al., bioRxiv - Bioengineering 2021

  Quote: ... and Murine IFN-gamma were respectively purchased from R&D system (Minneapolis, MN) and Peprotech (Rocky Hill ...
• The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development

  Ella Thomson, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Antibodies used were Anti-SOX3 (R&D Systems, AF2569, 1/200), Anti-Nestin (Abcam AB82375 ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and treated with 50 ng/ml of recombinant TRAIL (R&D Systems) for 4 hrs ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: MDA231-LM2 cells in DMEM with 10% FBS were cultured with or without incremental dosages (10-200 ng/ml) of recombinant OPG (R&D Systems) for 30 min ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: SUM159-LM1 cells or MDA231-LM2 cells were suspended in HuMEC/0.1% BSA and treated with EC-derived conditioned media (CM) (diluted 2-5 times in the final medium) or 50 ng/ml of recombinant activin B (R&D systems). 2,500 cells/well of SUM159-LM1 cells or 5,000 cells/well of MDA231-LM2 cells were seeded on 96-well ultra-low attachment plate (Corning) ...
• Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

  Tsunaki Hongu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or anti-TNFα (AF-410, R&D Systems, 10 μg/ml) at 4°C overnight ...
• A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

  Yang Yang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 0.2 mM E2 conjugase (UbcH5c, #E2-627 R&D systems, or RAD6 #E2-613 R&D Systems), 0.2 mM E3 ligase (recombinant bacterial RAD18-RAD6 complex or RNF168 both purified in-house) ...
• A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

  Yang Yang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 0.2 mM E2 conjugase (UbcH5c, #E2-627 R&D systems, or RAD6 #E2-613 R&D Systems), 0.2 mM E3 ligase (recombinant bacterial RAD18-RAD6 complex or RNF168 both purified in-house) ...
• A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

  Yang Yang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 0.1 mM E1 Ubiquitin Activating Enzyme (#E-304 R&D systems), 0.2 mM E2 conjugase (UbcH5c ...
• A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

  Yang Yang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 75 mM ubiquitin (#U-100H R&D systems) 1.6 mM FLAG-PCNA substrate (expressed and purified in bacteria) ...
• A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

  Yang Yang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1x Energy regeneration solution (#B-10 R&D systems), 75 mM ubiquitin (#U-100H R&D systems ...
• Reconstructing human early embryogenesis in vitro with pluripotent stem cells

  Berna Sozen, et al., bioRxiv - Developmental Biology 2021

  Quote: ... FGF4 (25 ng/mL; R&D Systems, 5846-F4) and heparin (1 mg ml−1 ...
• Establishment of a Patient-Derived, Magnetic Levitation-Based, 3D Spheroid Granuloma Model for Human Tuberculosis

  Leigh A. Kotze, et al., bioRxiv - Immunology 2021

  Quote: ... and tumor necrosis factor (TNF)α (R&D Systems®, LXSAHM-04). Briefly ...
• Establishment of a Patient-Derived, Magnetic Levitation-Based, 3D Spheroid Granuloma Model for Human Tuberculosis

  Leigh A. Kotze, et al., bioRxiv - Immunology 2021

  Quote: ... A one-plex kit was used to measure the production of interleukin (IL)-22 (R&D Systems®, LXSAHM-01), and a four-plex was used to measure the production of IL-2 ...
• γδT Cells Are Required for CD8⁺ T Cell Response to Vaccinia Viral Infection

  Rui Dai, Xiaopei Huang, Yiping Yang, bioRxiv - Immunology 2021

  Quote: ... and interleukin 4 (IL-4; 500 U/mL; R&D Systems). GM-CSF and IL-4 were replenished on day 2 and 4 ...
• γδT Cells Are Required for CD8⁺ T Cell Response to Vaccinia Viral Infection

  Rui Dai, Xiaopei Huang, Yiping Yang, bioRxiv - Immunology 2021

  Quote: ... the bone marrow cells were culture in 6-well plates at density of 3×106 cells/mL in 3mL DC medium in the presence of mouse granulocyte macrophage-colony stimulating factor (GM-CSF; 1000 U/mL; R&D Systems, Minneapolis, MN) and interleukin 4 (IL-4 ...
• A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection

  Luise Hassler, et al., bioRxiv - Pathology 2021

  Quote: ... an ACE2 antibody AF933 (R&D Systems) was used (16 ...
• Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia

  Yoko Miura, et al., bioRxiv - Pathology 2021

  Quote: ... mouse anti-TGF-β and goat anti-Serpin F1/PEDF (R&D Systems), rabbit anti-Uteroglobin ...
• Anti-GD2 antibody disrupts GD2:Siglec-7 interactions and synergizes with CD47 blockade to mediate tumor eradication

  Johanna Theruvath, et al., bioRxiv - Immunology 2021

  Quote: ... 4 μg/mL of each Siglec-Fc (R&D Systems) was pre-complexed with either 8 μg/mL AffiniPure Donkey anti-human IgG Alexa Fluor 647 (Jackson ImmunoResearch ...
• DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

  Tincy Simon, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PDX1 (1:100, R&D Systems, mouse, MAB2419)) and SOX9 (1:100 ...
• DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

  Tincy Simon, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 2.5µm FFPE sections were used for ARX (1:1500, R&D Systems, sheep, AF7068), PDX1 (1:100 ...
• Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

  Roberto R. Ricardo-Gonzalez, et al., bioRxiv - Immunology 2021

  Quote: ... or rmIL-13 (2 μg, R&D systems) in calcium- and magnesium-free phosphate buffered saline (PBS) ...
• Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

  Roberto R. Ricardo-Gonzalez, et al., bioRxiv - Immunology 2021

  Quote: ... mice were injected subcutaneously with IL-4 complex (IL-4c) comprised of rmIL-4 (2 μg, R&D systems) combined with anti-IL-4 antibody 10 μg ...
• Fasciola hepatica fatty acid binding protein (Fh12) induces apoptosis and tolerogenic properties in murine bone marrow derived dendritic cells

  Caleb Ruiz-Jiménez, et al., bioRxiv - Immunology 2021

  Quote: ... and 20ng/ml GM-CSF (R&D System) at 37°C ...
• Innate triggering and antiviral effector functions of activin A

  K. Al-Hourani, et al., bioRxiv - Immunology 2021

  Quote: Concentration of Activin A in human and mouse serum samples were performed using sandwich ELISA-Activin A immunoassay kit from R&D system (Cat DAC008).
• The RNA sensor MDA5 detects SARS-CoV-2 infection

  Natalia G. Sampaio, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stimulated with IFN-A/D (R&D Systems) at 100 U/ml overnight ...
• Parental-fetal interplay of immune genes leads to intrauterine growth restriction

  Gurman Kaur, et al., bioRxiv - Immunology 2021

  Quote: ... and Endoglin/CD105 (R&D systems) were measured in plasma samples collected from pregnant mice on gd18.5 ...
• Parental-fetal interplay of immune genes leads to intrauterine growth restriction

  Gurman Kaur, et al., bioRxiv - Immunology 2021

  Quote: ... PIGF-2 (R&D systems) and Endoglin/CD105 (R&D systems ...
• Parental-fetal interplay of immune genes leads to intrauterine growth restriction

  Gurman Kaur, et al., bioRxiv - Immunology 2021

  Quote: Mouse VEGF R1/Flt-1 (R&D systems), PIGF-2 (R&D systems ...
• Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation

  Thomas Keating, et al., bioRxiv - Immunology 2021

  Quote: ... or recombinant ficolin-3 (R&D systems) or human purified C1q (Comp Tech ...
• Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation

  Thomas Keating, et al., bioRxiv - Immunology 2021

  Quote: ... recombinant MBL (R&D systems) (100 µg mL-1 ...
• Prostaglandin E₂ induction by cytosolic Listeria monocytogenes in phagocytes is necessary for optimal T-cell priming

  Courtney E. McDougal, et al., bioRxiv - Immunology 2021

  Quote: ... anti-MARCO polyclonal Goat IgG-Biotin (R&D Systems, BAF2956), and FITC-conjugated COX2 polyclonal antibody (Cayman Chemical ...
• IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii

  Sambamurthy Chandrasekaran, et al., bioRxiv - Neuroscience 2021

  Quote: The clearance assay in human neurons was performed as described for primary pure murine neurons except that human IFN-γ (R&D Systems, Cat # 285-MI-100) was used for pre-stimulation.
• Circulating Low Density Neutrophils of Breast Cancer Patients are Associated with their Worse Prognosis due to the Impairment of T cell Responses

  Diana P. Saraiva, et al., bioRxiv - Immunology 2021

  Quote: ... and CCL17 (R&D Systems), in the patients’ plasma was measured using ELISA technique ...
• CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

  Minh Ma, et al., bioRxiv - Immunology 2021

  Quote: ... were purchased from R&D Systems. AF647 Goat anti-human IgG(H+L ...
• CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

  Minh Ma, et al., bioRxiv - Immunology 2021

  Quote: ... PE anti-human NKG2C/CD159c antibody (clone 134591, R&D Systems) were purchased from R&D Systems ...
• Pre-diabetes increases tuberculosis disease severity, while high body fat without impaired glucose tolerance is protective

  Roma Sinha, et al., bioRxiv - Immunology 2021

  Quote: ... and IL-10 were performed by ELISA according to the manufacturer’s instructions (R&D Systems).
• Effect of chronic JUUL aerosol inhalation on inflammatory states of the brain, lung, heart and colon in mice

  Alex Moshensky, et al., bioRxiv - Immunology 2021

  Quote: Cytokine and chemokine levels were assessed in the BAL with Duo-Set Enzyme-Linked Immunosorbent Assays (R&D Systems Inc., Minneapolis, MN). ELISAs were performed per manufacture’s instructions.