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1 - 50 of 8115 citations for 8 Chloro 4 methyl 1 2 dihydroquinolin 2 one since 2019

• Social memory in female mice is rapidly modulated by 17β-estradiol through ERK and Akt modulation of synapse formation

  Paul A. S. Sheppard, et al., bioRxiv - Neuroscience 2022

  Quote: ... or 10ng/side of PI3K inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002; Santa Cruz Biotechnology, Dallas, TX); or vehicle (50% dimethyl sulfoxide [DMSO] in 0.9% NaCl solution ...
• Erosion of X-Chromosome Inactivation in female hiPSCs is heterogeneous and persists during differentiation

  Ana Cláudia Raposo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 5-(methyl-2H3)-2′-deoxycytidine (#SC-217100, Santa Cruz), 5-(hydroxymethyl)-2′-deoxycytidine-2H3 (#H946632 ...
• Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aging Brain

  Samantha Mancino, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5-(methyl-2H3)-2′-deoxycytidine (Cat# SC-217100, Santa Cruz), 5-(hydroxymethyl)-2′-deoxycytidine-2H3 (Cat# H946632 ...
• miRNA mediated downregulation of non-muscle Cyclase associated protein 1 is required for myogenic differentiation

  Anurag Kumar Singh, et al., bioRxiv - Cell Biology 2021

  Quote: ... Myosin Heavy chain 1/2/4/6 (1:1000, Santa Cruz), GAPDH (1:3000 ...
• Endogenous retroviruses promote prion-like spreading of proteopathic seeds

  Shu Liu, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti PiT-2 B-4 (1:1000; Santa Cruz Biotechnology); rabbit anti-V5 D3H8Q (1:1000 ...
• Analysis of alternative mRNA splicing in vemurafenib-resistant melanoma cells

  Honey Bokharaie, Walter Kolch, Aleksandar Krstic, bioRxiv - Cancer Biology 2022

  Quote: ... ppERK1/2 (E-4) (1/10,000 dilution, #sc-7383, Santa Cruz, Mouse), tERK1/2 (1/10,000 dilution ...
• miR-203 drives breast cancer cell differentiation

  Nuria G. Martínez-Illescas, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Aldh1/2 (mouse monoclonal H-8, Santa Cruz Biotechnology, sc-166362), CK8/18 (rabbit monoclonal EP17/EP30 ...
• miRNA mediated downregulation of non-muscle Cyclase associated protein 1 is required for myogenic differentiation

  Anurag Kumar Singh, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following antibodies were used: Myosin Heavy chain 1/2/4/6 (1:500, Santa Cruz) and secondary antibodies conjugated with Alexa488 (1:500 ...
• Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cells

  Evan P.S. Pratt, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... 8MM-IBMX (3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione) was purchased from Santa Cruz Biotechnology (Dallas ...
• Hydroxylation of Actin Impairs Cell Motility Through Blocking its’ Histidine Methylation

  Zhenzhen Zi, et al., bioRxiv - Biochemistry 2021

  Quote: ... Anti-CUL-2 Antibody (C-4) (Santa Cruz, sc-166506), Anti-Flag (Sigma ...
• Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

  Toyoshi Yanagihara, et al., bioRxiv - Molecular Biology 2022

  Quote: ... BMP-2/4 (sc-137087, Santa Cruz for western blot), BMP2 (PA578874 ...
• A Novel Chromatin-Opening Element for Stable Long-term Transgene Expression

  Shireen S. Rudina, Christina D. Smolke, bioRxiv - Synthetic Biology 2019

  Quote: ... cells were transduced at varying dilutions of the lentiviral stock (ranging from 1:2 to 1:100) in DMEM + 10% FBS with 8 μg/mL polybrene (Santa Cruz Biotechnologies). Media was refreshed on P19 cells 24 h after transduction ...
• Neural mechanism of acute stress management by trace aminergic signalling in the lateral habenula

  Soo Hyun Yang, et al., bioRxiv - Neuroscience 2022

  Quote: ... Membranes were immunoblotted overnight at 4°C with anti-GFP (1:1000; B-2, Santa Cruz) as the primary antibody ...
• Time to lysis determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system

  Brian Y. Hsueh, et al., bioRxiv - Microbiology 2023

  Quote: ... Phage lysates were treated for 2 hr at 37°C either with 0.01 M methyl methanesulfonate (MMS) (Santa Cruz Biotechnology) or equal volume of phage buffer (100 μM Tris pH 7.5 ...
• N-cadherin-Presented Slit Repulsive-Cues Direct Collective Schwann cell Migration

  Julian J A Hoving, et al., bioRxiv - Molecular Biology 2019

  Quote: ... AKT 1/2/3 (Santa Cruz), Slit2 (Abcam ab134166 ...
• Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause

  Nina E. Baumgartner, et al., bioRxiv - Neuroscience 2021

  Quote: ... BCL-2 (Santa Cruz, 1:2000), ChAT (Cell Signalling ...
• Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

  Brandon Elliott, et al., bioRxiv - Physiology 2024

  Quote: ... polycystin 2 (1:100; Santa Cruz). Primary antibodies were detected with fluorescent secondary antibodies (Alexa Fluor 488 ...
• scRNA-Sequencing uncovers a TCF-4-dependent transcription factor network regulating commissure development

  Marie-Theres Wittmann, et al., bioRxiv - Genomics 2020

  Quote: ... Germany)] and 2 μl of ms TCF-4-antibody (Santa Cruz, sc393407), 2 μl of ms BrdU-antibody (BD Bioscience ...
• Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury

  Ayşe N. Ozantürk, et al., bioRxiv - Immunology 2022

  Quote: ... Cells were blocked by adding 2% bovine serum albumin (9048-46-8, Santa Cruz Biotechnology) in PBS for 30 min at RT followed by washing twice with PBS ...
• Profiling of Nascent Lariat Intermediates Reveals Key Genetic Determinants of the Timing of Human Co-transcriptional Splicing

  Yi Zeng, et al., bioRxiv - Molecular Biology 2021

  Quote: K562 cells at 90% confluency were treated for 2 hours with one of the following reagents (1) pladienolide B (Santa Cruz Biotechnology) in DMSO to a final concentration of 10 μM or (2 ...
• Extracellular communication between brain cells through functional transfer of Cre mRNA

  David Rufino-Ramos, et al., bioRxiv - Cell Biology 2023

  Quote: ... Lamp-2 (Santa Cruz, sc18822, 1:1000), TSG101 (BD Biosciences BD612696 ...
• Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

  Hélène Lasolle, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (1:400; Santa Cruz Biotechnology), and β-Actin (1:1,1000 ...
• Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

  Shiekh Tanveer Ahmad, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Nuclei were counterstained in 4’,6-diamidino-2-phenylindole (DAPI; Santa Cruz) and mounted with FluorSave Reagent (Calbiochem) ...
• Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells

  Lisa Weixler, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-tubulin 1:5000 (B-5-1-2 Santa Cruz). For slot blotting ...
• Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells

  William H. Palmer, et al., bioRxiv - Immunology 2022

  Quote: ... or SHP-2 (B-1; Santa Cruz Biotechnology; 1:1000). Membranes were washed five times in TBST ...
• Vascular Injury Changes Topology of Vessel Network to Adapt to Partition of Blood Flow for New Arteriovenous Specification

  Kyung In Baek, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and 4′,6-diamidino-2-phenylindole (SC-3598, Santa Cruz Biotechnology Inc., TX) were fluorescently labeled.
• Astrocyte-secreted glypican-4 drives APOE4-dependent tau pathology

  Sivaprakasam R. Saroja, et al., bioRxiv - Neuroscience 2021

  Quote: ... glypican-4 CRISPR/dCas9 lentiviral activation particles (sc-420640-LAC-2, Santa Cruz) were injected in the right CA1 region (AP-2 ...
• Fatty acid binding protein 5 forms higher order assemblies with FLAP or COX-2 in LPS-stimulated macrophages

  Shelby E. Elder, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-COX-2 (Santa Cruz, 1:100) were diluted in blocking solution overnight at 4 °C ...
• Base-resolution models of transcription factor binding reveal soft motif syntax

  Žiga Avsec, et al., bioRxiv - Genomics 2020

  Quote: ... ɑ-Pbx 1/2/3 (Santa Cruz, sc-888), and ɑ-Zic3 (Abcam ...
• The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases

  James L. J. Coleman, et al., bioRxiv - Biochemistry 2020

  Quote: ... TAPI-1 and TAPI-2 (Santa Cruz Biotechnology), and TIMP1 ...
• P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway

  Zhijia Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-IRS-2 (Santa Cruz Biotechnology, 1:1000); anti-phospho-Akt (Ser473 ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... TSG101 (1:100, clone C-2 Santa Cruz), GFAP (1:2000 ...
• Bioengineered human colon organoids with in vivo-like complexity and function

  Olga Mitrofanova, et al., bioRxiv - Bioengineering 2023

  Quote: ... mucin 2 (1:50, Santa Cruz sc-7314), chromogranin-A (1:100 ...
• HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming

  Xiaodong Lu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... the extracted lysates were first pre-cleared with protein G-magnetic beads at 4 °C for 2 h followed by incubation with HOXB13 antibody (2 μg/sample, Santa Cruz, sc-28333) overnight ...
• Leucine zipper-based sorting system enables generation of multi-functional CAR T cells

  Scott E. James, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... Transfected cells were selected one day after transfection with puromycin 2 μg/mL (Santa Cruz Biotech, sc-108071B) or blasticidin 10 μg/mL (Santa Cruz Biotechnology ...
• The adenoviral E1B-55k protein present in HEK293 cells mediates abnormal accumulation of key WNT signaling proteins in large cytoplasmic aggregates

  Petter Angell Olsen, Stefan Krauss, bioRxiv - Cell Biology 2021

  Quote: ... Tankyrase-1/2 (E10) (Santa Cruz Biotechnology; sc-365897; 1:40), AXIN1 (C76H11 ...
• Functionalized Biomimetic Hydrogels Enhance Salivary Stem/Progenitor Cell Organization

  Mariane Martinez, et al., bioRxiv - Bioengineering 2021

  Quote: ... N-(2-Hydroxyethyl)piperazine-N-(4-butanesulfonic acid) (HEPBS) was purchased from Santa Cruz Biotechnology ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... IMP1/2/3 (sc-271785; Santa Cruz; 1:1000), citrate synthase (G-3 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... GFP (1:1,000, Santa Cruz Biotechnology, clone B-2), Parkin (1:1,000 ...
• THE STABILIZATAION OF C-MYC BY THE NOVEL CELL CYCLE REGULATOR, SPY1, DECREASES EFFICACY OF BREAST CANCER TREATMENTS

  Rosa-Maria Ferraiuolo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-ERK1/2 (Santa Cruz Biotechnology; 1:1000). Secondary antibodies were used at 1:10000 dilution in blocker for 1 hour at room temperature ...
• Sugar transporter Slc37a2 regulates bone metabolism via a dynamic tubular lysosomal network in osteoclasts

  Pei Ying Ng, et al., bioRxiv - Cell Biology 2022

  Quote: ... pERK1/2 (Santa Cruz sc-7383, 1/500 dilution), t-ERK1/2 (Promega V114A ...
• Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

  Rachel Ulferts, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-ATP6V1B1/2 (sc55544, Santa Cruz, WB 1:1000), anti-FLAG (F1804 ...
• Identification of SSX2IP/Msd1 as a Wtip-binding partner by targeted proximity biotinylation

  Bo Xiang, et al., bioRxiv - Biochemistry 2021

  Quote: ... GFP (1:1000, B-2, Santa Cruz, mouse monoclonal), Biotin (1:10000 ...
• PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 controls the transport of E-cadherin

  Giovanna Grimaldi, et al., bioRxiv - Cell Biology 2020

  Quote: ... tankyrase-1/2-rabbit polyclonal antibody (Santa Cruz Biotechnology) was used at 1:1000 for western blotting ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti Erk1/2 (1:5000; Santa Cruz Biotechnology), rabbit anti-TrkB (1:1000 ...
• Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine β-hydroxylase deficient mice

  Darshana Kapri, et al., bioRxiv - Neuroscience 2022

  Quote: ... 2) goat DCX (1:250; Santa Cruz Biotechnology, USA); 3 ...
• CDK4/6 inhibition and dsRNA sensor agonism co-operate to enhance anti-cancer effects through ER stress and immune modulation of tumour cells

  Victoria Roulstone, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PARP-1 (F-2) (sc-8007, Santa Cruz Biotechnology), anti-DNMT (ab92314 ...
• ER Stress Impedes Regulated Secretion by Governing Key Exocytotic and Granulogenic Molecular Switches

  Mohima Mukherjee, et al., bioRxiv - Cell Biology 2023

  Quote: ... EF-2 (Santa Cruz Biotechnology, SC-166415, 1:5000) and B-TUB (Proteintech ...
• Dynamic mRNA stability changes buffer transcriptional activation during neuronal differentiation and are regulated by RNA binding proteins

  Yuan Zhou, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MAP-2 (Santa Cruz, Cat# Sc-5359, 1:50), β-tubulin-III (Cell signaling ...
• Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease

  Zsuzsanna Lichner, et al., bioRxiv - Cell Biology 2024

  Quote: ... Polycystin 2 (1:500, sc-28331, Santa Cruz Biotechnology), MRTF-A (1:1000 ...