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1 - 50 of 7772 citations for 7 CHLORO 3 PHENYL PYRAZOLO 1 5 A PYRIMIDINE since 2019

• The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa

  Annette Brandel, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells were cultivated four days in the presence of 2.5 μM D-threo-l-phenyl-2-palmitoylarmino-3-morpholino-l-propanol (PPMP; Santa Cruz) to inhibit synthesis of glucosylceramide-based GSLs [41].
• Phosphatidylinositol 4-kinase III beta regulates cell shape, migration and Focal Adhesion number

  Patricia Bilodeau, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5’-ATAAGCTCCCTGCCCGAGTC-3’ (Santa Cruz sc-430739).
• High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

  Ok-Hee Kim, et al., bioRxiv - Physiology 2019

  Quote: ... NHERF1 (A-7, 1:200; Santa Cruz), and SLC34A1 (ab182099 ...
• IL8 Drives an Elaborate Signal Transduction Process for CD38 to Produce NAADP from NAAD and NADP⁺ in Endolysosomes to Effect Cell Migration

  Tae-Sik Nam, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Rab-7 (1:2500; Santa Cruz Biotechnology), anti-EEA-1 (1:2500 ...
• EPAC2 is required for corticotropin-releasing hormone-mediated spine loss

  Zhong Xie, Peter Penzes, Deepak P. Srivastava, bioRxiv - Neuroscience 2019

  Quote: ... EPAC2 monoclonal (A-7, Santa Cruz, 1:200); CRHR1 polyclonal (EB08035 ...
• Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

  Loganathan Palanikumar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... which was blocked with 5% nonfat milk and then incubated with mouse anti-p53 antibody DO-7 (1:1000; Santa Cruz), or anti-β-actin antibody (1:2000 ...
• Subcellular dynamics and functional activity of the cleaved Na⁺ channel β1 subunit intracellular domain

  Alexander S. Haworth, et al., bioRxiv - Cell Biology 2021

  Quote: ... N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester (DAPT) (1 μM, 24 h, Santa Cruz Biotech) and L-685,458 (1 - 10 μM ...
• Temporal coordination of collective migration and lumen formation by antagonism between two nuclear receptors

  Xianping Wang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-HA(1:100, F-7, Santa Cruz), rabbit anti-Baz (1:400 ...
• Poly(ADP-ribose) potentiates ZAP antiviral activity

  Guangai Xue, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-HA [F-7] (1:3000; Santa Cruz), mouse anti-β-Actin [C4] (1:3000 ...
• DTX3L and USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels

  Yashwanth Ashok, et al., bioRxiv - Biochemistry 2023

  Quote: ... HA-Tag (F-7) (#sc7392; 1:1000; Santa Cruz), and against α-tubulin (clone B-5-1-2 ...
• CHI3L1 enhances melanoma lung metastasis via regulation of t cell co-stimulators and CTLA-4/B7 axis

  Bing Ma, et al., bioRxiv - Immunology 2022

  Quote: ... anti-mouse B7-1 (F-7, Santa Cruz Biotechnology) and anti-mouse B7-2 (BU63 ...
• BCL6 is a context-dependent mediator of the glioblastoma response to irradiation therapy

  Anna K.W. Tribe, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 5 µg N-3 anti-BCL6 antibody (Santa Cruz, USA) was added to five of the tubes and 5 µg non-specific Invitrogen™ normal rabbit IgG antibody (Thermo Fisher Scientific ...
• A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins

  Weichao Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-HRS (1:500, C-7, Santa Cruz Biotechnology), mouse anti-HA (1:1000 ...
• Regulation of Macrophage IFNγ-Stimulated Gene Expression by the Transcriptional Coregulator CITED1

  Aarthi Subramani, et al., bioRxiv - Immunology 2022

  Quote: ... MSG-1 (CITED1; D-7, sc-393585, Santa Cruz Biotechnology), and STAT1 (D1K9Y ...
• Syndecan-4^-/- mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and Notch/HES-1 pathways, and alterations in extracellular matrix components

  Sissel Beate Rønning, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Pax-7 (1:500, sc-81648, 1:500, 1x casein, Santa Cruz) anti-decorin (1:500 ...
• Social memory in female mice is rapidly modulated by 17β-estradiol through ERK and Akt modulation of synapse formation

  Paul A. S. Sheppard, et al., bioRxiv - Neuroscience 2022

  Quote: ... or 10ng/side of PI3K inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002; Santa Cruz Biotechnology, Dallas, TX); or vehicle (50% dimethyl sulfoxide [DMSO] in 0.9% NaCl solution ...
• The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

  Peter D. Szigetvari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Pan14-3-3 (#sc-629, Santa Cruz Biotech; 1:1000), DHFR (#133546 ...
• Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

  Stewart W.C. Masson, et al., bioRxiv - Systems Biology 2023

  Quote: ... 14-3-3 (Santa Cruz #sc-1657; diluted 1:5000). The following day membranes were washed 3 x 10 minutes in TBS-T and incubated for 1 hour in species-appropriate fluorescent or HRP secondary antibodies ...
• Inducible expression of Oct-3/4 reveals synergy with Klf4 in targeting Cyclin A2 to enhance proliferation during early reprogramming

  Lamuk Zaveri, Jyotsna Dhawan, bioRxiv - Cell Biology 2021

  Quote: ... 5 μg of polyclonal anti-Oct-3/4 (Santa Cruz, USA), polyclonal anti-Klf4 (R & D Systems ...
• Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole

  Jierui Zhao, et al., bioRxiv - Plant Biology 2022

  Quote: ... 1 μM concanamycin A (conA) (CAS 80890-47-7; Santa Cruz); 50 μM 2,4-dinitrophenol (DNP ...
• Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins

  Susanna Cogo, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse α-pan 14-3-3 (sc-1657, Santa Cruz Biotechnology, 1:1000 to 1:10000), α-Flag® M2-HRP (A8592 ...
• N-cadherin-Presented Slit Repulsive-Cues Direct Collective Schwann cell Migration

  Julian J A Hoving, et al., bioRxiv - Molecular Biology 2019

  Quote: ... AKT 1/2/3 (Santa Cruz), Slit2 (Abcam ab134166 ...
• Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

  Namgyu Lee, et al., bioRxiv - Biochemistry 2023

  Quote: ... treated with 5 mM Glutamate and/or 3 µM selenide (Santa Cruz). After 12 hr ...
• Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

  Brianna K. Unda, et al., bioRxiv - Neuroscience 2022

  Quote: ... Mouse anti-HA (Santa Cruz Biotechnology F-7; Western Blot 1:500), Rabbit anti-Ankyrin-G (Synaptic Systems 386 003 ...
• Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate

  Yueh-Fu O. Wu, et al., bioRxiv - Cell Biology 2021

  Quote: ... and LIS-1 - mouse monoclonal antibody H-7 (Santa Cruz, sc-374586). All labeled secondary antibodies were obtained from Invitrogen ...
• Single-cell assessment of trophoblast stem cell-based organoids as human placenta-modeling platforms

  Matthew J. Shannon, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse monoclonal anti-cytokeratin 7 (clone RCK105; 1:100; Santa Cruz Biotechnology), rabbit monoclonal anti-EGR1 (1:50 ...
• Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury

  Qing Zhao, et al., bioRxiv - Neuroscience 2024

  Quote: ... Interferon regulatory factor 7 (IRF7, Cat# sc-74471, Santa Cruz, 1:50), Signal transducer and activator of transcription 1 (STAT1 ...
• The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway

  Alberto Carreño, Jens Lykke-Andersen, bioRxiv - Molecular Biology 2022

  Quote: ... mouse monoclonal anti-14-3-3 (Santa Cruz Biotechnology, sc-1657; 1:1,000), rabbit polyclonal anti-TTP (Sigma-Aldrich ...
• RSV protects bystander cells against IAV infection by triggering secretion of type I and type III interferons

  Maciej Czerkies, et al., bioRxiv - Immunology 2022

  Quote: ... anti-IRF-3 (D-3) (Santa Cruz Biotechnology, cat. sc-376455, 1:500), anti-Respiratory Syncytial Virus antibody (Abcam ...
• Spatial, Quantitative and Functional Deconstruction of Virus and Host Protein Interactions Inside Intact Cytomegalovirus Particles

  Boris Bogdanow, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-pan 14-3-3 (1:50, clone H8, sc-1657, Santa Cruz) and anti-PP1 (1:50 ...
• The critical role of HDAC1 activates NSCLC growth by nicotine resistance Cisplatin

  Ching-Yi Peng, Jia-Ping Wu, bioRxiv - Molecular Biology 2020

  Quote: ... HDAC1 small interfering RNAs (HDAC1 siRNAs): 5”-CCCAUAACUUGCUGUUAAA-3’ (Santa Cruz Biotechnology, Inc.) using Lipofectamine 2000 reagent (Invitrogen) ...
• A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

  Emily R. Hildebrandt, et al., bioRxiv - Biochemistry 2023

  Quote: ... mouse anti-DnaJA2(7) monoclonal (1:500 dilution, Santa Cruz Biotech. sc-136515); mouse anti-HIS his.h8 monoclonal (1:1000 dilution ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-pan-14-3-3 (B-8) (Santa Cruz Biotechnology, sc-133233, 1:1000), anti-14-3-3η (D23B7 ...
• Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

  Osama Garwain, et al., bioRxiv - Biochemistry 2020

  Quote: ... Membranes were treated with antibodies diluted 1:1000 in 0.5% BSA and washed 3 times for 5 min before applying secondary antibiotic (anti-mouse or anti-goat from Santa Cruz Biotechnology and Anti-Rabbit from Abcam at a concentration of 1:1000 ...
• Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression

  Tiantian Wu, et al., bioRxiv - Cell Biology 2019

  Quote: ... Coilin (Santa Cruz, F-7); Fibrillarin (Santa Cruz ...
• Gαi2-Mediated Regulation of Microtubules Dynamics and Rac1 Activity Orchestrates Cranial Neural Crest Cell Migration in Xenopus

  Soraya Villaseca, et al., bioRxiv - Cell Biology 2023

  Quote: ... ζ-PKC (Santa Cruz, (B-7), sc-393218 ...
• DDX24, a D-E-A-D box RNA helicase, is required for muscle fiber organization and anterior pole specification essential for head regeneration in planarians

  Souradeep R. Sarkar, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Anti-Gα q/11/14 (G-7) (1:200 Santa Cruz Biotechnology, sc-365906) antibody staining was performed in formaldehyde-fixed samples after RNA-FISH was performed on them ...
• Hyperactive PI3Kinase delta enables long distance regeneration of the rat corticospinal tract

  Kristyna Karova, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-PKCγ (1:1000, Santa Cruz, Dallas, TX, USA, sc166451 A-7 clone), mouse anti-cFOS (1:500 ...
• The genetic and dietary landscape of the muscle insulin signalling network

  Julian van Gerwen, et al., bioRxiv - Systems Biology 2023

  Quote: ... total PRAS40 (Cell Signaling Technologies #2691, diluted 1:1000, and 14-3-3 (Santa Cruz #sc-1657, diluted 1:5000). The following day membranes were washed 3 x 10 min in TBS-T and incubated for 1 h in species-appropriate fluorescent antibodies ...
• Antagonism between viral infection and innate immunity at the single-cell level

  Frederic Grabowski, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-IRF-3 (clone D-3) (catalog number sc-376455; Santa Cruz Biotechnology; 1:500), anti-Respiratory Syncytial Virus (catalog number ab20745 ...
• Base-resolution models of transcription factor binding reveal soft motif syntax

  Žiga Avsec, et al., bioRxiv - Genomics 2020

  Quote: ... ɑ-Pbx 1/2/3 (Santa Cruz, sc-888), and ɑ-Zic3 (Abcam ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti- caveolin-3 (Santa Cruz Biotechnology, 1:100), anti-desmin (abcam ...
• Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α

  Gemma Molinaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... Then 10% of the lysate was set aside for use as an input control and the rest was tumbled overnight at 4°C with 7 µl of ERα antibody or 1.4 µg of Homer antibody (Santa Cruz Biotechnology, D-3). The same isotype IgG was used as control for the specificity of the ERα (Abcam #ab172730 ...
• Plasma membrane protrusions mediate host cell-cell fusion induced by Burkholderia thailandensis

  Nora Kostow, Matthew D. Welch, bioRxiv - Cell Biology 2022

  Quote: ... The membrane was then washed 3 × 5 min in TBS-T and incubated with 1:5000 goat anti-rabbit HRP secondary antibody (Santa Cruz Biotechnology, sc-2004) in 5% milk in TBS-T for 1 h followed by 3 × 5 min washes in TBS-T ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... The membrane was incubated with the following primary antibodies in TBST + 5% BSA at 4°C overnight: rabbit polyclonal anti-MEK-3 (1:500, Santa Cruz Biotechnology, #sc-961), rabbit polyclonal anti-p38 (1:1000 ...
• ETV7 reduces inflammatory responses in breast cancer cells by repressing TNFR1/NF-κB axis

  Erna Marija Meškytė, et al., bioRxiv - Cancer Biology 2022

  Quote: ... which was probed over-night at 4°C with specific antibodies diluted in 1-3% skimmed milk-PBS-0.1% Tween solution: TNFR1 (H-5, Santa Cruz Biotechnologies, DBA, Milan, Italy), STAT3 (124H6 ...
• Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

  Yang Jiao, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-c-myc (PE10, 1:1,000, SC-40), anti-HA-probe (F-7, 1:1,000, SC-7392) (Santa Cruz Biotechnology ...
• Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

  Namgyu Lee, et al., bioRxiv - Biochemistry 2023

  Quote: ... HT29 cells were treated with 5 mM Glutamate and/or 3 µM selenide (Santa Cruz). After 2 hr and 24 hr incubation for SK-Hep1 and 12hr for HT29 cells ...
• The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

  Samuel Rivero-Hinojosa, et al., bioRxiv - Genomics 2021

  Quote: ... Tubulin was detected using 1:5000 anti-α Tubulin B-7 (sc-5286, Santa Cruz) and 1:2000 of an anti-mouse secondary antibody (sc-2005 ...
• The SARS-CoV-2 spike protein binds and modulates estrogen receptors

  Oscar Solis, et al., bioRxiv - Immunology 2022

  Quote: ... and HA-probe (F-7) mouse IgG2a mAb (Santa Cruz Biotech, sc-7392X, 1:1,000), OctA-probe (anti-flag ...