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1 - 50 of 623 citations for 7 Bromo 1H indazole 3 carboxylic acid since 2019

• Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas

  Devin Dersh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-CIITA (clone 7-1H, Santa Cruz); anti-B2M (Dako) ...
• P4HA2: A link between tumor-intrinsic hypoxia, partial EMT and collective migration

  Vaishali Aggarwal, et al., bioRxiv - Cancer Biology 2022

  Quote: ... P4HA2 was inhibited by using 20 μmol/L 1,4-dihydrophenonthrolin-4-one-3-carboxylic acid (1,4-DPCA) (SC-200758, Santa Cruz, USA). 1,4-DPCA ...
• Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cells

  Evan P.S. Pratt, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... 8MM-IBMX (3-Isobutyl-8-(methoxymethyl)-1-methyl-1H-purine-2,6(3H,7H)-dione) was purchased from Santa Cruz Biotechnology (Dallas ...
• A Legionella pneumophila effector impedes host gene silencing to promote virulence

  Justine Toinon, et al., bioRxiv - Molecular Biology 2022

  Quote: ... cells were then treated for 1h with 25 μg/mL of Caffeic Acid Phenethyl Ester inhibitor (CAPE, Santa Cruz Biotechnology, sc-200800) or DMSO ...
• Amphipathic helices of cellular proteins can replace the helix in M2 of Influenza A virus with only small effects on virus replication

  Bodan Hu, et al., bioRxiv - Cell Biology 2019

  Quote: ... blocked (3% BSA in PBS for 1h) and incubated with primary anti-M2 mAb14C2 (1:300 in PBS supplemented with 3% BSA, Santa Cruz) for 1h and then with anti-mouse secondary antibody coupled to Alexa Fluor 488 (1:1000 ...
• Seipin traps triacylglycerols to facilitate their nanoscale clustering in the ER membrane

  Xavier Prasanna, et al., bioRxiv - Cell Biology 2020

  Quote: ... Indole-3-acetic acid sodium (IAA, Santa Cruz, sc-215171, 500 µM); Human fibronectin (Roche Diagnostics ...
• Caltubin regulates microtubule stability via Ca²⁺-dependent mechanisms favouring neurite regrowth

  Andrew Barszczyk, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mouse anti-His6 (1:100; 1h for immunocytochemistry) (#sc-8036; Santa Cruz Biotechnology); goat anti-mouse-488 (1:200 ...
• Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression

  Tiantian Wu, et al., bioRxiv - Cell Biology 2019

  Quote: ... Coilin (Santa Cruz, F-7); Fibrillarin (Santa Cruz ...
• Gαi2-Mediated Regulation of Microtubules Dynamics and Rac1 Activity Orchestrates Cranial Neural Crest Cell Migration in Xenopus

  Soraya Villaseca, et al., bioRxiv - Cell Biology 2023

  Quote: ... ζ-PKC (Santa Cruz, (B-7), sc-393218 ...
• Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α

  Gemma Molinaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... Then 10% of the lysate was set aside for use as an input control and the rest was tumbled overnight at 4°C with 7 µl of ERα antibody or 1.4 µg of Homer antibody (Santa Cruz Biotechnology, D-3). The same isotype IgG was used as control for the specificity of the ERα (Abcam #ab172730 ...
• Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice

  Seref Gul, et al., bioRxiv - Molecular Biology 2021

  Quote: ... membranes were incubated 1h with appropriate HRP conjugated secondary mouse (Santa Cruz SC-358920) or rabbit (Cell Signaling ...
• The RSK-RPS6 Axis Controls the Preconditioning Effect and Induces Spinal Cord Regeneration

  Charlotte Decourt, et al., bioRxiv - Neuroscience 2022

  Quote: ... neurons were treated 1h after plating with RSK inhibitor BRD7389 at 3uM (Santa Cruz), mTOR inhibitors Torin1 5nM (Santa Cruz ...
• Plasticity of extrachromosomal and intrachromosomal BRAF amplifications in mediating targeted therapy dosage challenges

  Kai Song, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BRAF (F-7, Santa Cruz Biotechnology), BRAF (C-19 ...
• Loss of mutant TP53 does not impair the sustained proliferation, survival or metastasis of diverse cancer cells

  Zilu Wang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TP53 (clone DO-7, Santa Cruz) and TrP53 (clone CM5 ...
• Unraveling the roles of Mast4 in amelogenesis via regulating DLX3 and stem cell maintenance of mouse incisors

  Dong-Joon Lee, et al., bioRxiv - Developmental Biology 2021

  Quote: ... HA(F-7, Santa Cruz Biotechnology), Flag (F3165 ...
• Unfolded Protein Response Factor ATF6 Augments T Helper Cell Responses and Promotes Mixed Granulocytic Airway Inflammation

  Dandan Wu, et al., bioRxiv - Immunology 2023

  Quote: ... and pSTAT3 (B-7, Santa Cruz). STAT6 ChIP primers were ...
• A mitochondria-regulated p53-CCF circuit integrates genome integrity with inflammation

  Karl N. Miller, et al., bioRxiv - Cell Biology 2023

  Quote: ... HA-probe (F-7) (Santa Cruz Biotechnology Cat#sc-7392 ...
• MARK3-mediated Slingshot-1 phosphorylation is essential for polarized lamellipodium formation

  Toshiaki Mishima, et al., bioRxiv - Cell Biology 2023

  Quote: ... MARK3 (G-7; Santa Cruz Biotechnology), and β-actin (AC15 ...
• Mutational Analysis of an Antimalarial Drug Target PfATP4

  Swaksha Rachuri, et al., bioRxiv - Microbiology 2024

  Quote: ... samples were blocked w/v 3% BSA for 90 minutes and then incubated with monoclonal anti-mouse HA antibody (F-7, sc-7392, Santa Cruz Biotechnology, Lot # 12923) at 1:500 and rabbit anti-PyEXP2 primary antibody (a gift from Dr ...
• Identification of Relevant Genetic Alterations in Cancer using Topological Data Analysis

  Raúl Rabadán, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Sections were incubated with anti-ADAMTS12 (H-142, Santa Cruz Biotechnologies, 1h at 37 °C) or with anti-Ki67 (ab66155 ...
• Suramin potently inhibits binding of the mammalian high mobility group protein AT-hook 2 to DNA

  Linjia Su, et al., bioRxiv - Biochemistry 2019

  Quote: ... cells were incubated for 1h with Rabbit polyclonal IgG E-cadherin antibody (Santa Cruz, sc-7870) followed by incubation of Alexa 488 Goat anti-Rabbit secondary antibody for 1h ...
• Destabilization of the holo-DNA Polδ by loss of Pol32 confers conditional lethality that can be suppressed by stabilizing Pol31-Pol3 interaction

  Kenji Shimada, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Monoclonal anti-HA (F-7, Santa Cruz) was used to precipitate HA-tagged DNA pol α ...
• High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

  Ok-Hee Kim, et al., bioRxiv - Physiology 2019

  Quote: ... NHERF1 (A-7, 1:200; Santa Cruz), and SLC34A1 (ab182099 ...
• Crif1 Promotes Osteoporosis in Mice after Radiation

  Lixin Xiang, et al., bioRxiv - Cell Biology 2019

  Quote: ... RANK (H-7) (sc-374360; Santa Cruz), A-FABP (AP2 ...
• Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer

  José Manuel García-Martínez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... stained with 7-AAD (Santa Cruz Biotechnology) for 10 min at 37°C ...
• Synaptic plasticity via receptor tyrosine kinase/G protein-coupled receptor crosstalk

  Cristina Lao-Peregrin, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-Gαi3 (Santa Cruz, H-7). Antibodies for immunocytochemistry were TrkB (R&D ...
• The Arabidopsis receptor kinase STRUBBELIG regulates the response to cellulose deficiency

  Ajeet Chaudhary, et al., bioRxiv - Plant Biology 2019

  Quote: Jasmonic acid-d0 and jasmonic acid-d5 were obtained from Santa Cruz Biotechnology ...
• The BUBR1 pseudokinase domain promotes efficient kinetochore PP2A-B56 recruitment to regulate spindle checkpoint silencing and chromosome alignment

  Luciano Gama Braga, et al., bioRxiv - Cell Biology 2019

  Quote: ... Okadaic Acid (Santa Cruz Biotechnology ...
• Polyunsaturated phospholipids increase cell resilience to mechanical constraints

  Linette Kadri, et al., bioRxiv - Cell Biology 2020

  Quote: ... Arachidonic Acid (AA) and Docosa Hexaenoic Acid (DHA) (Santa Cruz Biotechnology, Dallas, USA), were prepared in absolute ethanol at 100 mM ...
• Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas

  Devin Dersh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-14-3-3 (Santa Cruz).
• SOD2 in Skeletal Muscle: New Insights from an Inducible Deletion Model

  Aowen Zhuang, et al., bioRxiv - Physiology 2021

  Quote: ... pan 14-3-3 (Santa Cruz), phospho-T172 AMPKalpha (Cell Signaling) ...
• Proteomic analysis identifies novel binding partners of BAP1

  Roy Baas, et al., bioRxiv - Biochemistry 2021

  Quote: ... HAT1 (H-7, SC-390562, Santa Cruz Biotechnology), Goat anti-Rabbit IgG (H+L ...
• IL8 Drives an Elaborate Signal Transduction Process for CD38 to Produce NAADP from NAAD and NADP⁺ in Endolysosomes to Effect Cell Migration

  Tae-Sik Nam, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-Rab-7 (1:2500; Santa Cruz Biotechnology), anti-EEA-1 (1:2500 ...
• EPAC2 is required for corticotropin-releasing hormone-mediated spine loss

  Zhong Xie, Peter Penzes, Deepak P. Srivastava, bioRxiv - Neuroscience 2019

  Quote: ... EPAC2 monoclonal (A-7, Santa Cruz, 1:200); CRHR1 polyclonal (EB08035 ...
• Induction of the nicotinamide riboside kinase NAD⁺ salvage pathway in skeletal myopathy of H6PDH KO mice

  Craig L. Doig, et al., bioRxiv - Physiology 2019

  Quote: ... alpha-Tubulin (Santa Cruz B-7 sc-5286). Secondary antibodies (Dako ...
• Native MOWChIP-seq: Genome-wide profiles of key protein bindings reveal functional differences among various brain regions

  Zhengzhi Liu, et al., bioRxiv - Genomics 2021

  Quote: ... anti-HDAC2 (ab124974, lot GR97402-7, Santa Cruz). The suspension was incubated on a rotator at 4°C for 2 h ...
• The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial infection

  Orsolya Bilkei-Gorzo, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-Syntaxin 7 (Santa Cruz Biotechnology: sc-514017) was diluted 1:10 in 5% BSA in PBS and incubated overnight at 4°C ...
• Bradycardic mice undergo effective heart rate improvement after specific homing to the sino-atrial node and differentiation of adult muscle derived stem cells

  Pietro Mesirca, et al., bioRxiv - Cell Biology 2020

  Quote: ... with mouse anti-Connexin45 (G-7, Santa Cruz) or with mouse anti-cdc6 antibody (37F4 from Molecular Probes) ...
• Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection

  Stephanie J. Melchor, et al., bioRxiv - Immunology 2019

  Quote: ... anti-ATGL (Santa Cruz Biotechnology, clone F-7), anti-HSL (Cell Signaling Technology ...
• PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20

  James Bancroft, et al., bioRxiv - Cell Biology 2020

  Quote: ... CDC20 (mouse mAb clone E-7, Santa Cruz sc-13162 ...
• Huntingtin bundles and changes the local proteome of actin filaments in neurons

  Rémi Carpentier, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-JIP1 (B-7, Santa Cruz Biotechnology) diluted 1:500 ...
• Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

  Jing Zhao, et al., bioRxiv - Cell Biology 2022

  Quote: ... the membrane was incubated for 1h using an appropriate Horseradish Peroxidase (HRP)-conjugated secondary antibody (Santa Cruz Biotechnology) at room temperature ...
• Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity

  Liora S. Katz, et al., bioRxiv - Cell Biology 2024

  Quote: ... and Pan-14-3-3 (Santa Cruz) antibodies were conjugated to Duolink oligonucleotides ...
• A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

  Dick J.H. van den Boomen, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse anti-Ccz1 (B-7, Santa Cruz, #sc-514290), mouse anti-EEA1 (14/EEA1 ...
• Temporal coordination of collective migration and lumen formation by antagonism between two nuclear receptors

  Xianping Wang, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-HA(1:100, F-7, Santa Cruz), rabbit anti-Baz (1:400 ...
• Replication intermediate architecture reveals the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

  Yann Benureau, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse anti-polη (B-7, Santa Cruz #sc-17770), rabbit-anti PrimPol (kind gift from L ...
• Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction

  Reina E. Ito, Chitose Oneyama, Kazuhiro Aoki, bioRxiv - Cancer Biology 2020

  Quote: ... anti-Raf-B (F-7) was from Santa Cruz Biotechnology.
• GFI1 cooperates with IKAROS/IKZF1 to activate gene expression in T-cell acute lymphoblastic leukemia

  Wenxiang Sun, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-α-tubulin (Santa Cruz, B-7, sc-5286); anti-FLAG (Sigma ...
• HDAC inhibitors decrease TLR7/9-mediated human plasmacytoid dendritic cell activation by interfering with IRF-7 and NF-κB signaling

  Dante B. Descalzi-Montoya, et al., bioRxiv - Immunology 2020

  Quote: ... and Zenon-labeled (Invitrogen)-anti-IRF-7-AF488 (clone, G-8, Santa Cruz) or AF488 Zenon-labeled (Invitrogen ...
• Poly(ADP-ribose) potentiates ZAP antiviral activity

  Guangai Xue, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-HA [F-7] (1:3000; Santa Cruz), mouse anti-β-Actin [C4] (1:3000 ...