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1 - 50 of 760 citations for Hemoglobin Colorimetric Detection Kit 2 plate since 2019

• High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells

  Kayleigh Slater, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and a detection kit (Bond Polymer Refine Red Detection Kit; Leica Biosystems ...
• Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

  Steven T. Chen, et al., bioRxiv - Immunology 2022

  Quote: ... Polymer detection system (Bond Polymer Refine Detection Kit #DS9800, Leica Biosystems) was used for horseradish peroxidase signal amplification ...
• High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

  Christopher R. Merritt, et al., bioRxiv - Pathology 2019

  Quote: ... Secondary detection was performed this the Bond Polymer Refine Detection Kit (Leica, DS9800). Tissue sections were imaged using a Nikon Eclipse Ci light microscope with 4x or 20x objectives and Nikon Elements software.
• Imbalanced immune response and dysregulation of neural functions underline fatal opportunistic encephalitis caused by astrovirus

  Olga A. Maximova, et al., bioRxiv - Microbiology 2022

  Quote: ... Detection was completed using the Bond Research Detection kit (Leica Biosystems; CAT# DS9455). Nuclei were counterstained with DAPI (Vector Laboratories) ...
• Commercial influenza vaccines vary in both the structural arrangements of HA complexes and in induction of antibodies to cross-reactive HA epitopes

  Mallory L. Myers, et al., bioRxiv - Microbiology 2022

  Quote: ... Detection with DAB chromogen was completed using the Bond Polymer Refine Detection kit (Leica Biosystems). Slides were finally cleared through gradient alcohol and xylene washes prior to mounting and coverslipping ...
• Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters

  Xueqiao Liu, et al., bioRxiv - Microbiology 2022

  Quote: ... Detection with DAB chromogen was completed using the Bond Polymer Refine Detection kit (Leica Biosystems). The VisUCyte anti-goat horseadish peroxidase (HRP ...
• Tissue-resident FOLR2⁺ macrophages associate with tumor-infiltrating CD8⁺ T cells and with increased survival of breast cancer patients

  Rodrigo Nalio Ramos, et al., bioRxiv - Immunology 2021

  Quote: ... with Bond Polymer refine detection kit (Leica, DS9800). Antigen retrieval was performed in BOND Epitope Retrieval Solution 1 (Leica ...
• Morphofunctional evaluation of the adrenal gland in rats submitted to nutritional restriction during pregnancy

  Bruno dos Santos Telles, et al., bioRxiv - Cell Biology 2022

  Quote: ... a Novolink Polymer Detection Systems Kit (RE7280K; Leica Biosystems Newcastle L10 ...
• Allergic Asthma Responses Are Dependent on Macrophage Ontogeny

  Robert M. Tighe, et al., bioRxiv - Immunology 2023

  Quote: ... utilizing the Bond Research Detection kit (Leica Microsystems) and Opal fluorophores (Akoya Biosciences) ...
• MicroRNA-194 promotes lineage plasticity in advanced prostate cancer

  Rayzel C. Fernandes, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Sections were stained using a Leica BOND-MAX-TM autostainer with BondTM epitope retrieval 1 or 2 and the Bond Refine Detection Kit (Leica). Primary antibodies are listed in Supplementary Table S1.
• Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission

  Zarna Rajeshkumar Pala, et al., bioRxiv - Microbiology 2023

  Quote: ... Detection with DAB chromogen was completed using the Bond Polymer Refine Detection kit (Leica Biosystems, #DS9800). Slides were finally cleared through gradient alcohol and xylene washes prior to mounting and placing cover slips ...
• The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

  Tuba Barut, et al., bioRxiv - Microbiology 2022

  Quote: ... BondTM Polymer Refine Detection visualisation kit (Leica Byosystems, Germany) was afterwards used for signal detection using DAB as chromogen and counterstaining with hematoxylin.
• Multimodally trackable and clinically translatable platform for modelling human demyelinating brain diseases by temporally dispersed chemically induced lesions in the pig brain

  Mihai Ancău, et al., bioRxiv - Neuroscience 2023

  Quote: ... the BOND Polymer Refine Detection Kit (Leica Biosystems, UK) was used ...
• TPX2 expression promotes sensitivity to dasatinib in breast cancer by activating the YAP transcriptional signaling

  Carlos Marugán, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and the BOND Polymer Refine Detection kit (Leica Biosystems), following the manufacturer’s instructions ...
• Atypical Chemokine Receptor 1 (Ackr1)-deficient Mice Resist Lethal SARS-CoV-2 Challenge

  Shamik Majumdar, et al., bioRxiv - Immunology 2023

  Quote: ... Detection with DAB chromogen was completed using the Bond Polymer Refine Detection kit (Leica Biosystems, Catalog # DS9800). Slides were finally cleared through graded alcohol and xylene washes prior to mounting and placing cover slips.
• Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease

  Gerald Wai-Yeung Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibody incubations were followed by signal detection using BOND Polymer Refine Detection Kit (Leica Biosystems, IL, USA) with Mayer’s hematoxylin nuclear counter stain as per manufacturer’s instructions ...
• Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane

  Lili Zhao, et al., bioRxiv - Microbiology 2020

  Quote: ... Histological analysis of the 2 µm paraffin-embedded tissue sections was performed with the Bond Polymer Refine Detection Kit (Leica, Wetzlar, Germany) on a BondMax system (Leica) ...
• Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing

  Li Wang, et al., bioRxiv - Genomics 2020

  Quote: ... Peroxide block (Bond Polymer Refine Detection Kit [DS9800], Leica Biosystems) was applied for blocking the tissue endogenous peroxidase activity for 15 mins ...
• Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

  Teresa Gagliano, et al., bioRxiv - Cancer Biology 2019

  Quote: ... using the bond polymer refine detection kit (DS9800, Leica Biosystems). The antibody was incubated for 1 hour at a concentration of 1:100 ...
• Epithelial cells of the intestine acquire cell-intrinsic inflammation signatures during ageing

  Maja C. Funk, et al., bioRxiv - Genomics 2021

  Quote: ... using the Bond Polymer Refine Detection Kit (DS9800; Leica Biosystems). Sections were first applied to a peroxide blocking step for epitope retrieval using Epitope Retrieval Solution I and II (AR9640 ...
• A single cell atlas reveals distinct immune landscapes in transplant and primary tumors that determine response or resistance to immunotherapy

  Amy J. Wisdom, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Staining was completed with BOND Polymer Refine Detection kit (Leica) including DAB chromogen and hematoxylin nuclear stain ...
• Kinase Suppressor of RAS 1 (KSR1) maintains the transformed phenotype of BRAFV600E mutant human melanoma cells

  Zhi Liu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... using the Novolink Polymer Detection kit (Leica, Cat# RE7140-CE). Cells were counterstained with haematoxylin (Reagecon ...
• An unsupervised learning approach uncovers divergent mesenchymal-like gene expression programs across human neuroblastoma tumors, preclinical models, and chemotherapy-exposed tumors

  Richard H. Chapple, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and the Bond Polymer Refine Detection kit (DS9800, Leica Biosystems). Positive and negative tissue controls and isotype controls were used for examining the specificity of staining and species cross-reactivity for both PHOX2B and COL1A1 in comparison with the experimental tissue slides ...
• Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease

  Gerald Wai-Yeung Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... Using BOND Polymer Refine Detection Kit (Leica Biosystems, IL, USA) as described (52) ...
• Regulation of Non-Canonical Proteins Encoded by Small Open Reading Frames via the Nonsense-Mediated Decay Pathway

  Parthiban Periasamy, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bond Refine Detection Kit (Leica Biosystems, Newcastle Upon Tyne, UK), and Opal 6-Plex Detection Kit for Whole Slide Imaging (Akoya Biosciences ...
• Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

  Simon L. April-Monn, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Visualization used a Bond Polymer Refine Detection Kit (Leica, #DS9800) (RRID:AB_2891238 ...
• Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness

  Chiara Battistini, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and BOND IHC Polymer Detection Kit (Leica Biosystems, cat# DS9800) was used to stain the antibody with DAB Cromogen ...
• PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis

  Elliot Jokl, et al., bioRxiv - Cell Biology 2023

  Quote: ... Detection of the probes was performed through the BOND polymer Refine Red Detection and haematoxylin kit (DS9390, Leica Bond). Haematoxylin (blue ...
• Imbalanced immune response and dysregulation of neural functions underline fatal opportunistic encephalitis caused by astrovirus

  Olga A. Maximova, et al., bioRxiv - Microbiology 2022

  Quote: ... Brightfield colorimetric immunohistochemistry was performed using Bond RX (Leica Biosystems) according to manufacturer protocols ...
• Comparative analysis of Wnt signaling-related proteins in normal, benign, malignant and metastasised human liver tumors

  Bushra Kanwal, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and BOND Polymer Refine Detection kit (DS9800, Leica Biosystems, Newcastle, UK) according to manufacturer’s recommendations ...
• Lipid droplets are a metabolic vulnerability in melanoma

  Dianne Lumaquin, et al., bioRxiv - Cancer Biology 2022

  Quote: ... using the BOND Polymer Refine Red Detection Kit (Leica Biosystems, DS9390). Whole slide scanning was performed on an Aperio AT2 digital whole slide scanner (Leica Biosystems) ...
• Validation of a CRISPR/cas9-based technology platform for examining specific immune gene functions in an experimental murine model of IBD

  Rui Wang, et al., bioRxiv - Immunology 2019

  Quote: ... The Bond Polymer Refine DAB Detection kit (Leica Biosystems, DS9800 DAB) was used and all procedures followed manufacture’s protocols ...
• An autoregulatory feedback loop converging on H2A ubiquitination drives synovial sarcoma

  Nezha S. Benabdallah, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Staining was visualized using the BOND Polymer Refine Detection kit (Leica Biosystems ...
• A non-canonical function of LDHB promotes SLC7A11-mediated glutathione metabolism and protects against glutaminolysis-dependent ferroptosis in KRAS-driven lung cancer

  Liang Zhao, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Visualization was by the Bond Polymer Refine Detection kit (Leica Biosystems) as instructed by the manufacturer ...
• Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

  Suchira Gallage, et al., bioRxiv - Physiology 2023

  Quote: ... and staining using the Bond Polymer Refine Detection Kit (DS9800, Leica). Whole slides were then scanned using an Aperio AT2 slide scanner (Leica ...
• Beneficial effects of intermittent fasting in NASH and subsequent HCC development are executed by concerted PPARα and PCK1 action in hepatocytes

  Suchira Gallage, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and stained with the Bond Polymer Refine Detection Kit (DS9800, Leica). The slides were scanned with a whole-slide scanner (Aperio AT2 ...
• Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and hematoxylin (Bond Polymer Refine Detection Kit, Leica Microsystems, Cat# DS9800) according to the manufacturer’s protocol ...
• Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing

  Li Wang, et al., bioRxiv - Genomics 2020

  Quote: ... Primary antibody was incubated for a certain period of time depending on its optimized protocol and a polymer detection system (Bond Polymer Refine Detection Kit [DS9800], Leica Biosystems) was used afterwards for the secondary antibody and horse radish peroxidase (HRP ...
• Multidimensional single-cell analysis identifies a role of CD2-CD58 interactions for clinical antitumor T cell responses

  Gabrielle Romain, et al., bioRxiv - Immunology 2022

  Quote: ... The antibody was detected using Bond Polymer Refine Detection kit (Leica Biosystems) with diaminobenzidine (DAB ...
• An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

  Jürgen G. Okun, et al., bioRxiv - Physiology 2020

  Quote: ... and staining using the BondTM Polymer Refine Detection kit (DS9800, Leica Biosystems). Brightfield images were acquired using a Leica DM 1000 LED microscope and processed using Leica Application Suite software (Leica Biosystems).
• Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

  Steven T. Chen, et al., bioRxiv - Immunology 2022

  Quote: ... Slides were counterstained with hematoxylin (Bond Polymer Refine Detection Kit, DS9800, Leica Biosystems.
• Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients

  Tiziano A. Schweizer, et al., bioRxiv - Immunology 2021

  Quote: ... the slides were stained with the Bond Refine Detection Kit (Leica Biosystems), according to the manufacturer’s instruction ...
• Transcriptional analysis identifies overlapping and tissue-distinct profiles between Kaposi sarcoma tumors of the skin and gastrointestinal tract

  Ramya Ramaswami, et al., bioRxiv - Microbiology 2022

  Quote: ... and detected with DAB using the HRP Polymer Refine Detection Kit (Leica) and hematoxylin counterstaining ...
• Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade

  Daniel H. Shu, et al., bioRxiv - Immunology 2023

  Quote: ... Detection was performed using the Bond Polymer Refine Kit (DS9800, Leica Biosystems). For dual staining ...
• Unsupervised segmentation of 3D microvascular photoacoustic images using deep generative learning

  Paul W. Sweeney, et al., bioRxiv - Biophysics 2024

  Quote: ... with a bond polymer refine detection kit (Leica Biosystems, Milton Keynes,UK), and 3,3’-diaminobenzadine as a substrate ...
• 15-PGDH Inhibition Activates the Splenic Niche to Promote Hematopoietic Regeneration

  Julianne N.P. Smith, et al., bioRxiv - Cell Biology 2020

  Quote: ... and detection via Bond Polymer Refine Detection (Leica Biosystems) according to manufacturer’s protocol ...
• Therapeutic Targeting of 15-PGDH in Murine Idiopathic Pulmonary Fibrosis

  Julianne N.P. Smith, et al., bioRxiv - Pathology 2019

  Quote: ... and detection via Bond Polymer Refine Detection (Leica Biosystems) according to manufacturer’s protocol ...
• Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

  K. M. Hurskainen, et al., bioRxiv - Cell Biology 2019

  Quote: ... at 1:1500 dilution for 30 minutes followed by detection with horseradish peroxidase (HRP)-conjugated polymer system (Bond Polymer Refine Detection Kit, Leica, Concord, ON, Canada). All sections were then stained using 3,3’-Diaminobenzidine (DAB ...
• IER5, a DNA-damage response gene, is required for Notch-mediated induction of squamous cell differentiation

  Li Pan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Diaminobenzidine (DAB) staining was developed using the Bond Polymer Refine Detection Kit (Leica). Slides were counterstained with hematoxylin ...
• Low centrosome numbers correlate with higher aggressivity in ovarian cancer

  Jean-Philippe Morretton, et al., bioRxiv - Cancer Biology 2022

  Quote: ... blocking of endogenous peroxidase activity with Bond polymer refine detection kit (Leica: DS9800) (iii ...