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1 - 50 of 4813 citations for 8 CHLORO 2 METHYL IMIDAZO 1 2 A PYRIDINE 3 CARBOXYLIC ACID ETHYL ESTER since 2019

• CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia-induced invasion, and therapeutic resistance

  Jan C. Lumibao, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and matrix metalloproteinase 2 (MMP-2) (1:500, 10373-2-AP, Proteintech Group, Rosemont, IL) were analyzed using western blot ...
• DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION

  Mingzhuo Zhang, et al., bioRxiv - Physiology 2024

  Quote: ... Nedd4-2 (Proteintech, 13690-1-AP), WNK4 (Proteintech ...
• Ribosome-binding protein 1, RRBP1, maintains peroxisomal biogenesis

  Kaneez Fatima, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:2500 (Proteintech, 10181-2-AP); anti-LC3B 1:1000 (Novus biologicals ...
• Temporally and Spatially Regulated Collagen XVIII Isoforms Impact Ureteric Patterning Through Their TSP1-like Domain

  Mia M. Rinta-Jaskari, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Six-2 (11562-1-AP; Proteintech, 1:200), podocin (P0372 ...
• The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

  Francesca Finetti, et al., bioRxiv - Immunology 2020

  Quote: ... Postnuclear supernatants (2 mg/sample) were immunoprecipitated for 2 h using 2 μg of rabbit anti-IFT20 antibody (#13615-1-AP, Proteintech), anti-ATG16L1 antibody (#8089S ...
• VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells

  Jairo R. Temerozo, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-SREBP-2 (Proteintech #28212-1-AP) and anti-β-actin (Sigma ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... G3BP1 (Proteintech; 13057-2-AP; 1:2000), PABP1 (Cell Signaling Technologies ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... G3BP1 (Proteintech; 13057-2-AP; 1:2000), TAF-15 (Bethyl Laboratories ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... G3BP1 (Proteintech; 13057-2-AP; 1:2500), PABP1 (Cell Signaling Technologies ...
• Metabolic wastes are extracellularly disposed by excretosomes, nanotubes and exophers in mouse HT22 cells through an autophagic vesicle clustering mechanism

  Hualin Fu, et al., bioRxiv - Cell Biology 2019

  Quote: ... UBB (Proteintech 10201-2-AP, 1:200), LAMP2 (Proteintech 66301-1-Ig ...
• Legionella pneumophila regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector

  Lei Song, et al., bioRxiv - Microbiology 2021

  Quote: ... α-GST (Proteintech, cat# 66001-2, 1:10000), α-His (Sigma ...
• The outer mitochondrial membrane protein TMEM11 is a novel negative regulator of BNIP3/BNIP3L-dependent receptor-mediated mitophagy

  Mehmet Oguz Gok, Jonathan R. Friedman, bioRxiv - Cell Biology 2022

  Quote: ... anti-VDAC1/2 (Proteintech 10866-1-AP), anti-GAPDH (Proteintech 60004-1-Ig) ...
• Direct specification of lymphatic endothelium from non-venous angioblasts

  Irina-Elena Lupu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... PROX1 (Proteintech, #11067-2-AP, 1:100), PROX1 (Reliatech ...
• Renal ischemia-reperfusion injury attenuated by exosomes extracted from splenic ischemic preconditioning

  Liu Hongtao, Shen Ye, bioRxiv - Pathology 2022

  Quote: ... Bcl-2 (1:1000, Proteintech, Chicago, USA),respectively ...
• TRIM21–SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis

  Panpan Zhang, et al., bioRxiv - Cancer Biology 2019

  Quote: ... MYC (1:100, 60003-2-Ig, Proteintech), FLAG (1:100 ...
• EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

  Xianping Shi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-NKX2-2 (Proteintech, 13013-1-AP), anti-FLI-1 (Santa Cruz Biotechnology ...
• Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNA

  Laura E. Newman, et al., bioRxiv - Cell Biology 2022

  Quote: ... POLG2 (Proteintech #10997-2-AP, 1:100), mtSSB (Proteintech #12212-1-AP ...
• rtPA Directly Protects Neurons After Intracerebral Hemorrhage through PI3K/AKT/mTOR Pathway

  Jie Jing, et al., bioRxiv - Neuroscience 2023

  Quote: ... BAX (Proteintech, 50599-2-Ig, 1:1000), Beclin-1 (Proteintech ...
• Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis

  Emily Jean Wilson, et al., bioRxiv - Pathology 2023

  Quote: ... and COX-2 (Proteintech, 66351-1-Ig) were used ...
• Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

  José M. Liboy-Lugo, et al., bioRxiv - Cell Biology 2024

  Quote: ... G3BP1 (Proteintech, 13057-2-AP, 1:2000), and G3BP2 (Abcam ...
• Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

  Vasiliki-Ilya Gargareta, et al., bioRxiv - Neuroscience 2022

  Quote: ... tetraspanin-2 (TSPAN2, ProteinTech #20463-1-AP, 1:500), aspartoacylase (ASPA ...
• Tubular obstruction induced polycystin upregulation is pro-fibrotic and induced a severe cystic phenotype in adult mice with autosomal dominant polycystic kidney disease: the coexistence of polycystin loss and gain function in ADPKD

  Ming Wu, et al., bioRxiv - Pathology 2023

  Quote: ... anti-polycystin-2 (1:1000, 19126-1-AP, Proteintech), anti-polycystin-2 (1:1000 ...
• APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

  Michael S. Haney, et al., bioRxiv - Neuroscience 2023

  Quote: ... Cells were incubated in PBS with 3% donkey serum and the following primary antibodies overnight at 4 °C: rabbit anti-Perilipin 2 (1:200; Proteintech 15294-1-AP), rabbit anti-ACSL1 (1:100 ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-B-cell lymphoma-2 (BCL-2) polyclonal antibody (1:1,000 dilution, 26593-1-AP, Proteintech, Rosemont, IL, USA) and mouse anti-GAPDH monoclonal antibody (1:10,000 dilution ...
• Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus

  Gonca Bayraktar, et al., bioRxiv - Neuroscience 2019

  Quote: ... the dynabeads protein G were incubated with 2-3 µg of rabbit polyclonal CUL4B antibody (Proteintech, catalog #20882-1-AP) while gently rotating for 2h at 4°C ...
• Fast and unbiased purification of RNA-protein complexes after UV cross-linking

  Erika C Urdaneta, Benedikt M Beckmann, bioRxiv - Biochemistry 2019

  Quote: ... or anti-rabbitHRP (1:2500, Proteintech, SA00001-2) and Clarity ECL Western Blotting Substrate for chemiluminescence in a ChemiDocMP imaging system (BioRad).
• Regulation of the 20S proteasome by a novel family of inhibitory proteins

  Maya A Olshina, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-RBBP9 (1:1000, 12230-2-AP, Proteintech).
• Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome

  Na Xiao, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-AMPK (1:300, 10929-2-AP, Proteintech), anti-phospho-AMPKα1 (Ser473 ...
• CDNF rescues motor neurons in three animal models of ALS by targeting ER stress

  Francesca De Lorenzo, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-TDP43 (1:4,000; Proteintech, 10782-2-AP), and anti-Tuj1 (1:4,000 ...
• Legionella pneumophila regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector

  Lei Song, et al., bioRxiv - Microbiology 2021

  Quote: ... α-GFP (Proteintech, cat# 50430-2-AP, 1:5000), α-GST (Proteintech ...
• Mettl3-mediated m⁶A modification of Fgf16 restricts cardiomyocyte proliferation during heart regeneration

  Fu-Qing Jiang, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-GFP (Proteintech, 50430-2-AP, 1:200), and anti-Cardiac Troponin T (cTnT ...
• Subcellular localization of mutant P23H rhodopsin in an RFP fusion knockin mouse model of retinitis pigmentosa

  Michael A. Robichaux, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-centrin 2 (Proteintech, 15877-1-AP); rabbit anti-BiP (Abcam ...
• In vivo CGG repeat RNA binding protein capture identifies RAN translation modifiers and suppressors of repeat toxicity

  Indranil Malik, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:1000 SRSF1 (Rabbit, Proteintech 12929-2-AP), 1:1000 SRSF2 (Rabbit ...
• Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism

  Guangyi Luo, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-GLUT-2 (1:1000, Proteintech, China), rabbit anti-GS (1:1000 ...
• Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins

  John Fehilly, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-GFP (Proteintech, 50430-2-AP, 1:4000), anti-pan-14-3-3 (B-8 ...
• Subcellular proteome of radial glia reveals non-muscle myosins control basal endfeet to mediate interneuron organization

  Brooke R D’Arcy, et al., bioRxiv - Neuroscience 2022

  Quote: ... Anti-PSEM2 (ProteinTech, 12937-2-AP, 1:100) Mouse ...
• PXN/Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling

  Peigang Liang, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), mouse anti-α1 Na+/K+ ATPase (Abcam ...
• Propagation of neuronal micronuclei regulates microglial states

  Sarasa Yano, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Rab35 (11329-2-AP, Proteintech, 1:1000), anti-Tubulin (DM1A ...
• An uncanonical CDK6 activity inhibits cilia function by suppressing axoneme polyglutamylation

  Kai He, et al., bioRxiv - Cell Biology 2023

  Quote: ... GFP (50430-2-AP, Proteintech, dilution 1:1000), Flag (8146 ...
• PXN/Paxillin Phase Separation Promotes Focal Adhesion Assembly and Integrin Signaling

  Peigang Liang, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), rabbit anti-LIMD1 (Proteintech ...
• An ULK1/2-PXN mechanotransduction complex suppresses breast cancer cell migration

  Peigang Liang, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Kindlin-2 (Proteintech; 11453-1-AP), rabbit anti-HIC-5 (Proteintech ...
• Mapping RNA-Protein Interactions with Subcellular Resolution Using Colocalization CLIP

  Soon Yi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TIA1 (Proteintech, cat. #12133-2-AP, 1:500), GAPDH (Cell Signallng ...
• TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

  Yi Zeng, et al., bioRxiv - Neuroscience 2024

  Quote: ... TDP-43 (1:1,500, Proteintech 10782-2-AP), ELP1 (1:500 ...
• Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals

  Shuai-dong Chen, et al., bioRxiv - Immunology 2023

  Quote: ... and Igfbp3 (10189-2-AP, Proteintech, 1:100) were performed for to assess the angiogenesis and fibroblast migration respectively ...
• Induction of NASH in the Nwd1^−/− mouse liver via SERCA2-dependent endoplasmic reticulum stress

  Seiya Yamada, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-ADP/ATP translocase 1/2 (ANT1/2, rabbit polyclonal, #17796-1-AP, RRID: AB_2190358, Proteintech, Rosemont, IL, USA; 1:2000 for WB), anti-voltage-dependent anion-selective channel protein 1 (VDAC1)/porin (mouse monoclonal ...
• Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

  Vasiliki-Ilya Gargareta, et al., bioRxiv - Neuroscience 2022

  Quote: ... protein-arginine deiminase 2 (PADI2, Proteintech #12110-1-AP, 1:1000), tetraspanin-29 (CD9 ...
• Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

  Vasiliki-Ilya Gargareta, et al., bioRxiv - Neuroscience 2022

  Quote: ... peripheral myelin protein 2 (PMP2, ProteinTech #12717-1-AP, 1:500). Appropriate secondary anti-mouse or anti-rabbit antibodies conjugated to HRP were from Dianova (HRP goat-anti-mouse ...
• Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

  James L. Daly, et al., bioRxiv - Neuroscience 2022

  Quote: ... KEAP1 (Proteintech; 10503-2-AP; 1:1000 WB, 1:200 IF), LAMP1 (Developmental Studies Hybridoma Bank ...
• The versatility of Ascorbate Peroxidase-aided mapping uncovers insights of the nuclear lamina interactions and function

  Joseph R. Tran, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SRSF1 (1:2500, ProteinTech, #12929-2-AP).
• Sequestration of TDP-43^216-414 aggregates by cytoplasmic expression of the proSAAS chaperone

  Juan R. Peinado, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-TDP-43 (Proteintech 10782-2-AP, 1:1000), or anti-PGK1 (Invitrogen 459250 ...