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1 - 50 of 10000+ citations for IL 1 Alpha Human since 2019

• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-human IL-1β (1:1,000, #12242, Cell Signaling Technology), anti-IL-1β (1:1,000 ...
• Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes

  Haleema S. Malik, et al., bioRxiv - Immunology 2022

  Quote: ... rabbit-anti-mouse/human IL-1β (1:1000 dilution, number 12242; Cell Signaling), rabbit-anti-mouse/human polyclonal β-actin (1:1000 dilution ...
• Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the viral Core

  Anastasia Selyutina, et al., bioRxiv - Microbiology 2019

  Quote: ... and activated with IL-2 (100 U/ml) (Human IL-2; Cell Signaling Technology, #8907SF) and phytohemagglutinin (1 µg/ml ...
• TRIM5α restriction of HIV-1-N74D viruses in lymphocytes is caused by a loss of cyclophilin A protection

  Anastasia Selyutina, et al., bioRxiv - Microbiology 2020

  Quote: ... and activated with IL-2 (100 U/ml) (Human IL-2; Cell Signaling Technology, #8907SF) and phytohemagglutinin (1 µg/ml ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-alpha Tubulin (Cell Signaling, 1/2000), anti-beta Actin (Santa Cruz Biotechnology ...
• Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates

  Donghwi Bae, et al., bioRxiv - Cell Biology 2022

  Quote: ... alpha-TUBULIN (Cell Signaling 2144, 1:25), LAMP (DSHB ...
• Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

  Melica Nourmoussavi Brodeur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alpha-tubulin (2144S, Cell Signaling; 1:1000) and vinculin (sc-73614 ...
• Tuning of granulopoietic signaling by de novo designed agonists

  Timo Ullrich, et al., bioRxiv - Bioengineering 2023

  Quote: ... alpha-tubulin 1:1000 (Cell Signaling, #2144S), primary rabbit monoclonal antibodies against ...
• The Burkholderia cenocepacia type VI secretion system effector TecA is a virulence factor during lung infection

  Nicole A. Loeven, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit-anti-mouse/human IL-1β (Cell Signaling®, #12242), rabbit-anti-mouse/human polyclonal β-actin (Cell Signaling® ...
• Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses

  Cristina M. Failla, et al., bioRxiv - Cell Biology 2019

  Quote: ... Primary antibodies (anti-human IL-17RA antibody, Cell Signaling Technology, Danvers ...
• Identification of proximal SUMO-dependent interactors using SUMO-ID

  Orhi Barroso-Gomila, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-alpha-Actinin (1/5000) (Cell Signaling Technology); anti-Flag (1/1000) ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... acetylated-alpha-tubulin (1:500) (Cell Signaling Technologies) for the staining of ciliated cells ...
• Nuclear SUN1 Stabilizes Endothelial Cell Junctions via Microtubules to Regulate Blood Vessel Formation

  Danielle B Buglak, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-alpha-tubulin (1:500, 3873S, Cell Signaling), anti-GEF-H1 (1:500 ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... alpha-Tubulin (1:1000, Cell Signaling Technology, 2144), N-cadherin (1:1000 ...
• Immortalization and transformation of primary cells mediated by engineered ecDNAs

  Davide Pradella, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-alpha-tubulin (1:5000, Cell Signaling, #3873), anti-p53 (1:1000 ...
• Elevated plasma and urinary erythritol is a biomarker of excess simple carbohydrate intake in mice

  Semira R. Ortiz, Martha S. Field, bioRxiv - Biochemistry 2022

  Quote: ... and alpha-tubulin (1:1,000, Cell Signaling Technology). Secondary anti-rabbit antibody (1:100,000 ...
• ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

  Antentor Hinton Jr., et al., bioRxiv - Biophysics 2023

  Quote: ... Alpha Tubulin (1:1000; Cell Signaling Technology; #2144), and IP3R3 (1:1000 ...
• STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer

  Stephen D’Amico, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Hep3B cells were stimulated with human IL-6 (Cell Signaling Technology) at a concentration of 20ng/ml for 24 hours.
• Obesity Disrupts Pituitary UPR Leading to NAFLD

  Qingwen Qian, et al., bioRxiv - Physiology 2022

  Quote: ... IRE1 alpha (Cell Signaling, Cat No. 3294, 1:300), sXBP1 (Cell Signaling ...
• SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98

  Amin Addetia, et al., bioRxiv - Microbiology 2020

  Quote: ... and 1:1,000 anti-alpha Tubulin (Cell Signaling; clone DM1A), which was followed by staining with either 1:10,000 IRDye 680RD anti-Mouse IgG secondary antibody (Licor ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-alpha tubulin (Cell Signaling, #2144, 1:10000), followed by blotting with secondary antibodies peroxidase-conjugated goat anti-rabbit IgG (Jackson Lab ...
• Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models

  Lily L. Nguyen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... alpha-tubulin (Cell Signaling Cat ...
• Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD

  Jaspreet K. Osan, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-acetyl-alpha-tubulin rabbit monoclonal (1:500) (Cell Signaling Technologies), anti-TMPRSS2 mouse monoclonal (1:50 ...
• A high-content screen identified ingenol-3-angelate as an enhancer of B7-H3-CAR T cell activity by increasing B7-H3 protein expression on the target cell surface via PKCα activation

  Ha Won Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or 1:1000 anti-PKC-alpha antibody (Cell Signaling Technology, 2056S) with or without 1:10,000 anti-beta actin (Sigma ...
• Bi-steric mTORC1-selective Inhibitors activate 4EBP1 reversing MYC-induced tumorigenesis and synergize with immunotherapy

  Wadie D. Mahauad-Fernandez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and antibodies used—human c-MYC (D84C12) #5605 and alpha tubulin (DM1A) Mouse mAb #3873 from Cell Signaling Technologies—were previously described by our group39 ...
• An endometrial organoid model of Chlamydia-epithelial and immune cell interactions

  Lee Dolat, Raphael H. Valdivia, bioRxiv - Cell Biology 2020

  Quote: ... anti-acetylated-alpha-tubulin (Cell Signaling Technologies, Cat no. 5335S 1:200), anti-SEPT2 (Protein Tech ...
• Chromosome length and gene density contribute to micronuclear membrane stability

  Anna E Mammel, et al., bioRxiv - Cell Biology 2021

  Quote: ... Primary antibodies used: mouse alpha-tubulin (1:250; 3873S, Cell Signaling Technology), human anti-CREST (1:100 ...
• Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

  Matanel Yheskel, Simone Sidoli, Julie Secombe, bioRxiv - Genetics 2023

  Quote: ... rabbit anti-alpha-Tubulin (1:5000, Cell Signaling Technology Cat# 2144, RRID:AB_2210548). Secondary antibodies used were IRDye® 680RD Donkey anti-Mouse IgG (1:5000 ...
• Targeting LDHC dysregulates the cell cycle and improves sensitivity to cisplatin and olaparib

  Adviti Naik, Julie Decock, bioRxiv - Cancer Biology 2021

  Quote: ... acetylated alpha-tubulin (Cell Signaling), MAP1B (Abcam) ...
• LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation

  Francesca Pischedda, et al., bioRxiv - Neuroscience 2020

  Quote: ... alpha-Synuclein (D37A6-Cell Signaling); LC3 (NB100-2331-Novus Biologicals) ...
• ZDHHC5 targets Protocadherin 7 to the cell surface by a palmitoylation-dependent mechanism to promote successful cytokinesis

  Nazlı Ezgi Özkan Küçük, et al., bioRxiv - Cell Biology 2022

  Quote: ... Alpha Tubulin (Cell Signaling, 3873S), Tubulin (Abcam ...
• Spheroid architecture strongly induces miR-221/222 expression and promotes oxidative phosphorylation and survival of mobile tumor cells through a mechanism that includes restriction of miR-9 expression

  Avery S. Ward, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alpha-tubulin (Cell Signaling, 2144); Citrate synthetase (Abcam ...
• STAT3 but not STAT5 contributes to the protective effect of electro-acupuncture against myocardial ischemia/reperfusion injury

  Hui-Hui Guo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... IL-10 (1:1000, Cell Signaling, #4351), β-actin (1:1000 ...
• Chemotherapeutic regulation of the ROS/MondoA-dependent TXNIP/GDF15 axis; and derivation of a new organoid metric as a predictive biomarker

  Jinhai Deng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IL-1β (1:1000, Cell Signaling Technology), Caspase 1(1:1000 ...
• An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders

  Marie-France Dorion, et al., bioRxiv - Neuroscience 2023

  Quote: ... IL-1ý (1:500; #12242, Cell Signaling), NLR family pyrin domain containing 3 (NLRP3 ...
• miR-329 and miR-495-mediated Prr7 downregulation is required for homeostatic synaptic depression in rat hippocampal neurons

  Michiko O. Inouye, et al., bioRxiv - Neuroscience 2022

  Quote: ... Rabbit monoclonal anti-alpha Tubulin (1:2000 dilution, 11H10 lot 112125S, Cell signaling). HRP-conjugated secondary antibodies Rabbit anti-Ms IgG H&L (402335 lot D00160409 ...
• Manganese-dependent microRNA trimming by 3’→5’ exonucleases generates 14-nucleotide or shorter tiny RNAs

  GeunYoung Sim, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and/or anti-alpha-tubulin antibody (1:000 μg/mL, Cell Signaling Technology), and secondary antibodies ...
• Paxillin Promotes ATP-induced Activation of P2X7 Receptor and NLRP3 Inflammasome

  Wenbiao Wang, et al., bioRxiv - Immunology 2020

  Quote: ... mature IL-1β (Asp116 1:500, Cell Signaling), polyclonal rabbit anti-caspase-1 p10 (sc-515 ...
• A conformational switch driven by phosphorylation regulates Ykt6 activity in macroautophagy

  Kaitlyn McGrath, et al., bioRxiv - Cell Biology 2020

  Quote: ... alpha/beta-Tubulin (Cell Signaling, 2148S), and STX7 (Bethyl ...
• Targeting a proteolytic neo-epitope of CUB-domain containing protein 1 in RAS-driven cancer

  Shion A. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... alpha-Tubulin(DM1A) (Cell Signaling, 3873S), IRDye 680RD Goat anti-Mouse (LiCOR ...
• Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

  Toyoshi Yanagihara, et al., bioRxiv - Molecular Biology 2022

  Quote: ... alpha-Tubulin (#2144S, Cell Signaling Technology), PCNA (#2586S ...
• Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation

  Elizabeth M. Black, et al., bioRxiv - Cell Biology 2024

  Quote: ... alpha tubulin (Cell Signaling Technology, 3873), Chk2 (Cell Signaling Technology ...
• AAV-mediated interneuron-specific gene replacement for Dravet syndrome

  John K. Mich, et al., bioRxiv - Neuroscience 2023

  Quote: ... and loading control rabbit polyclonal anti-alpha tubulin (1/5000 dilution, Cell Signaling #2144S) or mouse anti-alpha tubulin clone DM1A (1/5000 dilution ...
• STING recruits NLRP3 to the ER and deubiquitinates NLRP3 to activate the inflammasome

  Wenbiao Wang, et al., bioRxiv - Immunology 2019

  Quote: ... or mature IL-1β (Asp116 1:500; Cell Signaling). Adherent cells in each well were lysed with the lyses buffer described below ...
• Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

  Emilie Abby, et al., bioRxiv - Cancer Biology 2021

  Quote: ... alpha-TUBULIN (Cell signaling, catalog no. 2125).
• Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis

  Sarah M. Ryan, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-alpha tubulin (Cell Signaling Technologies), mouse anti-Lamin 1:100 (DHSB) ...
• Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos

  Jing Fan, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-alpha-Tubulin (#2144, Cell signaling), horse radish peroxidase (HRP ...
• Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

  Nicholas L. Arp, et al., bioRxiv - Biochemistry 2023

  Quote: ... Anti-alpha-tubulin (Cell Signaling Technology, 3873S), Anti-beta-actin (Cell Signaling Technology ...
• Chronic dietary erythritol exposure elevates fasting plasma erythritol levels but does not cause weight gain or modify glucose homeostasis in mice

  Semira R. Ortiz, Martha S. Field, bioRxiv - Biochemistry 2021

  Quote: ... then incubated with primary antibodies (1:1000) against UCP1 and alpha-tubulin (Cell Signaling Technologies) for 1 hour at room temperature ...
• Multivalent coiled-coil interactions enable full-scale centrosome assembly and strength

  Manolo U. Rios, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary Antibodies: Mouse anti-alpha tubulin (1:1,000; Cell Signaling Technologies, Product # 3873S Lot #15); Goat anti-enhanced GFP (1:5,000 ...