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1 - 50 of 662 citations for 7 4 METHOXY PHENYL 4 7 DIOXO HEPTANOIC ACID since 2019

• Caspase3-deficient cells require fibronectin for protection against autophagy-dependent death

  David B. Weir, Lawrence H. Boise, bioRxiv - Cell Biology 2021

  Quote: ... Caspase-7 (Cell Signaling), Fibronectin (Abcam) ...
• Structures of BIRC6-Client Complexes Provide Mechanism of Smac-Mediated Release of Caspases

  Moritz Hunkeler, Cyrus Y. Jin, Eric S. Fischer, bioRxiv - Molecular Biology 2022

  Quote: ... casp-7 (Cell Signaling, 9492S), HtrA2 (Cell Signaling ...
• IRE1 RNase controls CD95-mediated cell death

  D Pelizzari-Raymundo, et al., bioRxiv - Cell Biology 2022

  Quote: ... Caspase-7 (Cell signaling, 12827), Caspase-9 (Cell signaling ...
• Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14

  Zoey A. Miller, et al., bioRxiv - Cancer Biology 2023

  Quote: ... caspase-7 (Cell Signaling #9492), cyclin D1 (Cell Signaling #2978) ...
• Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia

  Justin L. Blaize, et al., bioRxiv - Biochemistry 2023

  Quote: ... Caspase-7 (12827; Cell Signaling), CHK1 pS345 (2348T ...
• 1-deoxysphingolipid biosynthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

  Thekla Cordes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cells were then incubated with primary anti-RAB5 antibody at 4 °C overnight diluted in 8% BSA in PBST (1:500 dilution, Cat. #3547, lot 7, Cell Signaling Technology). Secondary anti-rabbit Alexa Fluor 568 antibody (1:1000 dilution ...
• Dynamics of p53 DNA binding sites contributes to functional selectivity of p53-driven gene expression

  Jessy Safieh, et al., bioRxiv - Biochemistry 2022

  Quote: ... The blots were subsequently incubated overnight at 4°C with primary antibodies against p53 (DO-7 mouse mAb, Cell Signaling, Cat # 48818) and β actin (13E5 rabbit mAb ...
• The RNA helicase DDX5 promotes alveolar rhabdomyosarcoma growth and survival

  Alberto Gualtieri, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cleaved caspase 7 (Cell signaling #8438), cleaved caspase 9 (Cell signaling #9505) ...
• Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism

  Akihiro Yamashita, et al., bioRxiv - Cell Biology 2023

  Quote: ... Cleaved Caspase-7 (Cell Signaling, 9491), CRABP2 (Proteintech ...
• SARS-CoV-2 spike protein induces brain pericyte immunoreactivity in absence of productive viral infection

  Rayan Khaddaj-Mallat, et al., bioRxiv - Neuroscience 2021

  Quote: Pericytes viability was assessed using the 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay according to the manufacturer’s procedure (Cell Signaling Technology). Cells were plated at the appropriate concentration in 96-well plates under different experimental conditions ...
• Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2

  Senem Merve Fred, et al., bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... pTRKB.Y706/7 (1:1000, #4621, Cell Signaling), pTRKB.Y816 (1:1000 ...
• Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guérin Effects in Lung Epithelial Cells

  Rui-ning Wang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-ATG 7 (8558; Cell Signaling Technology), anti-p62 (23214S ...
• DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

  Sarah Talley, et al., bioRxiv - Immunology 2021

  Quote: ... anti-caspase-7 (#9492, Cell Signaling Technology), anti-caspase-8 (#8592 ...
• Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia

  Justin L. Blaize, et al., bioRxiv - Biochemistry 2023

  Quote: ... Cleaved Caspase-7 (D198) (8438; Cell Signaling), Cleaved PARP (D214 ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... TCF1/7-PE-Cy7 (Cell Signaling Technology), Granzyme B-Alexa Fluor 700 (Biolegend) ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... TCF1/7-PE-Cy7 (Cell Signaling Technology), Granzyme B-Alexa Fluor 700 (Biolegend) ...
• Chromatin reorganization during myoblast differentiation involves the caspase-dependent removal of SATB2

  Ryan A.V. Bell, et al., bioRxiv - Molecular Biology 2019

  Quote: ... rabbit caspase 7 (9491S; Cell Signaling; 1:1000), mouse myosin heavy chain (DSHB ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved Caspase-7 (Asp198) (Cell Signaling Technology, 9491), cell cycle regulation antibody sampler kit (Cell Signaling Technology ...
• TGF-β1 inhibits cholesterol metabolism in hepatocytes to facilitate cell death, EMT and signals for HSC activation

  Sai Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... Caspase 7 antibody (cat. #9492, Cell Signaling Technology); cleaved Caspase 7 antibody (cat ...
• HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved Caspase-7 (1:1000, Cell Signaling Technology, #8438), cleaved PARP (1:1000 ...
• The DNA end-binding protein Ku associates with human telomeres primarily via protein-protein interactions

  Ann T. Sukumar, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 7 μl of anti-Ku80 antibody (2753, Cell signaling) was used ...
• A selective and rapid cell-permeable inhibitor of human caspase-3

  Angelo Solania, et al., bioRxiv - Biochemistry 2019

  Quote: ... anti-pro/caspase-7 (Cell Signaling 9492, 1:1000), anti-pro/caspase-8 (Cell Signaling 9746 ...
• Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis

  LaNisha L. Patterson, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit monoclonal α-Caspase-7 (9494S; Cell Signaling Technology), rabbit monoclonal α-Caspase-8 (4790T ...
• Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells

  G. Gemma Stathatos, et al., bioRxiv - Developmental Biology 2023

  Quote: ... cleaved Caspase 7 (9491, Cell Signaling Technology, 1:500), KATNA1 ...
• TGF-β1 inhibits cholesterol metabolism in hepatocytes to facilitate cell death, EMT and signals for HSC activation

  Sai Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved Caspase 7 antibody (cat. #8438, Cell Signaling Technology); Phospho-Smad2 (Ser465/467 ...
• Inhibiting DDX3X triggers tumor-intrinsic type I interferon response and enhances anti-tumor immunity

  Hyeongjwa Choi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-phospho-IRF-7 (Ser477) (#12390, Cell Signaling Technology), rabbit anti-Toll-like Receptor 3 (#6961 ...
• A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant promoting oncogene activation and tumorous transformation

  Jun Wang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit anti-Cleaved Caspase-7 (Cell Signaling Technology, Cat # 8438), and normal rabbit IgG (Cell Signaling Technology ...
• Apoptotic signaling clears engineered Salmonella in an organ-specific manner

  Taylor J. Abele, et al., bioRxiv - Immunology 2023

  Quote: ... cleaved caspase-7 (1:1000, rabbit, Cell Signaling Technology, Cat. 9491), cleaved caspase-3 (1:750 ...
• Harbingers of Aggressive Prostate Cancer: Precision Oncology Case Studies

  Joanna Cyrta, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53 (Cell Signaling Technologies, clone DO-7, 1/100, H1, 20min).
• Melanoblast transcriptome analysis reveals novel pathways promoting melanoma metastasis

  Kerrie L. Marie, et al., bioRxiv - Cancer Biology 2019

  Quote: ... β-Tubulin (9F3) Rabbit mAb (Cell Signaling Technology Cat# 2128, RRID:AB_823664, Lot# 7). For immunoblotting ...
• Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

  Caroline Frørup, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibodies used were anti-cleaved caspase-7 (#9491S, Cell Signaling, 1:500), anti-MHC-I (#ALX-805-711-C100 ...
• Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential

  Lisa D.J. Schiffelers, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit anti-caspase-7 clone D2Q3L (Cell Signaling Technology Cat#12827T, RRID:AB_2687912), mouse anti-caspase-8 clone 1C12 (Cell Signaling Technology Cat#9746S ...
• Fat Tissue Regulates the Pathogenesis and Severity of Cardiomyopathy in Murine Chagas Disease

  Kezia Lizardo, et al., bioRxiv - Pathology 2020

  Quote: ... Fatty acid binding protein (FABP)-4-specific rabbit monoclonal antibody (1:1000 dilution, D25B3, Cell Signaling), BNIP3 specific rabbit monoclonal antibody (1:1000 dilution ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Caspase 3/7 (1:300) [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

  Teresa Gagliano, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Primary antibodies (anti-fibroblasts clone TE-7, Millipore and phospho AKT/4060 Cell Signaling) were diluted in 3%BSA and incubated overnight at 4°C ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and for Caspase 3/7 1:300 [Cleaved Caspase-3 (Asp175) (5A1E) (Cell Signaling)] ...
• Functional Recovery of the Germ Line Following Splicing Collapse

  Wei Cao, et al., bioRxiv - Developmental Biology 2021

  Quote: ... mog-7::degron::gfp sample was incubated with 10μl IgG conjugated magnetic beads (Cell Signaling) as a control.
• POU2AF2/C11orf53 functions as a co-activator of POU2F3 by maintaining chromatin accessibility and enhancer activity

  Aileen Patricia Szczepanski, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cleaved Caspase 3 (#9664) and Cleaved-Caspase 7 (#8438) antibodies were purchased from Cell Signaling. Tubulin antibody (E7 ...
• A chromatin phase transition protects mitotic chromosomes against microtubule perforation

  Maximilian W. G. Schneider, et al., bioRxiv - Cell Biology 2021

  Quote: ... Cyclin B1 was detected with a monoclonal rabbit antibody (Cell Signaling, 12231S, 7, 1:800) and visualized using a donkey anti-rabbit Alexa Fluor 488 secondary antibody (Molecular Probes ...
• ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion

  Demis Menolfi, et al., bioRxiv - Genetics 2023

  Quote: ... Primary antibodies used in the study are: ATR(1: 1000, Cell signaling #2790, Lot.7), pKAP1 S824 (1:1000 ...
• Human GBP1 promotes pathogen vacuole rupture and inflammasome activation during Legionella pneumophila infection

  Antonia R. Bass, Sunny Shin, bioRxiv - Microbiology 2020

  Quote: ... caspase-4 (4450S; Cell Signaling), caspase-5 (D3G4W ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... ATF-4 (#11815, Cell signaling), LC3B (#NB600-1384 ...
• Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively

  Kanak Raina, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 4% formaldehyde (#12606P, Cell Signaling) was added to fix cells for 15 min at room temperature ...
• Dynamic analysis of pulsed cisplatin identifies effectors of resistance in lung adenocarcinoma

  Jordan F. Hastings, et al., bioRxiv - Cancer Biology 2019

  Quote: ... cleaved caspase 3 (#9661) and cleaved caspase 7 (#9491) antibodies were from Cell Signaling (MA, United States). The γH2A.X (S139 ...
• Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFкB p50 recruitment, and H3K9me2 deposition

  Veronica Elizabeth Burns, Tom Klaus Kerppola, bioRxiv - Immunology 2022

  Quote: ... αvinculin (Cell Signaling 4650T, lot 4), αlaminB1 (Cell Signaling 13435 ...
• Unique role for caspase-8 in the release of IL-1β and active caspase-1 from viable human monocytes during Toxoplasma gondii infection

  William J. Pandori, et al., bioRxiv - Immunology 2022

  Quote: ... caspase-4 (#4450; Cell Signaling Technology), caspase-8 (#9746 ...
• Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems

  Alessandra Tammaro, et al., bioRxiv - Pathology 2023

  Quote: ... total Histone 4 (Cell Signaling #2592), a-SMA (Dako M085101 ...
• Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer

  Jharna Datta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved caspase-7 (asp198, D6H1; cat# 8433, RRID:AB_11178377), and GAPDH (D16H11; cat# 8884, RRID:AB_11129865) were obtained from Cell Signaling Technology. Antibodies against ERβ (clone 68-4 ...
• Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence and late clinical metastasis in a Beclin-1-dependent manner

  Carole Nicco, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Secondary HRP-linked anti mouse IgG (7#076S) and anti rabbit IgG (#7074S) were from Cell Signaling Technology. K02288 (#AB-M2789-10MG) ...
• AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans

  Brendan J. Houston, et al., bioRxiv - Cell Biology 2023

  Quote: ... and dual stained with the transcription factor marker FOXO1 (day 7; 1 µg/ml, Cell Signaling Technology 2880) and differentiating spermatogonia marker c-KIT (day 7 ...