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1 - 50 of 506 citations for "ERK1 2" since 2019

• Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

  Avital Licht-Murava, et al., bioRxiv - Neuroscience 2022

  Quote: ... ERK1/2 (1:1000 mouse anti-total ERK1/2; Cell Signaling Technology #4696 ...
• ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS

  Andrea Magrì, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERK1/2 (Cell Signaling, Danvers ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #4370) ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... and Erk1/2 (Cell Signaling), mouse monoclonal antibodies to HA (16B12 ...
• Functional analysis of KIT gene structural mutations causing porcine dominant white phenotype by using genome edited mouse models

  Guangjie Sun, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Erk1/2 (#4695; Cell Signaling), Akt (#9272 ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 (4695, Cell Signaling), STAT3 (4904 ...
• Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

  Behnam Nabet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling, #4696), phospho-AKT S473 (Cell Signaling ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... phospho-Erk1/2 (Cell Signaling), cytochrome P450 reductase (Santa Cruz Biotechnology ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #9101) ...
• Hemodynamic stress activates inflammatory responses and cell death through spectrin-dependent modulation of Store Operated Calcium Entry

  Lance Hsieh, et al., bioRxiv - Cell Biology 2022

  Quote: ... ERK1/2 (4695, Cell Signaling), SPTAN1 (MAB1622 ...
• Oncogenic signaling alters cell shape and mechanics to facilitate cell division under confinement

  Helen K. Matthews, et al., bioRxiv - Cell Biology 2019

  Quote: ... ERK1/2 (Cell Signaling 9102), phospho-Akt (Ser473 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (4695, Cell Signaling), FGFR1 (9740 ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology), and phospho-ERK1/2 (Cell Signaling Technology) ...
• Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

  Hope E. Burks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling). The rabbit monoclonal antibody EP1576Y (ab52642 ...
• Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

  Damien M. Rasmussen, et al., bioRxiv - Biophysics 2023

  Quote: ... and ERK1/2 (Cell Signaling). Membranes were washed and incubated for 1 h at RT with corresponding species-reactive secondary antibody and then imaged using an Odyssey CLx near-infrared imager (LI-COR Biosciences).
• Calcium-Mediated Modulation of Blood-Brain Barrier Permeability by Laser Stimulation of Endothelial-Targeted Nanoparticles

  Xiaoqing Li, et al., bioRxiv - Bioengineering 2022

  Quote: ... P-p44/42 ERK1/2 and p44/42 ERK1/2 were purchased from Cell Signaling Technology. Gold (III ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 (Cell signaling, CST4695), anti-phospho-ERK1/2 (Cell Signaling ...
• PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism

  Luca Simula, et al., bioRxiv - Immunology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling 4695), anti-Hsp90 (Cell Signaling 4877) ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... Phospho- ERK1/2 (9101, Cell Signaling), phospho-STAT3 (9145 ...
• Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells via modulating metabolism and death pathways

  J Vial, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-ERK1/2 (9102, Cell signaling), anti-mTOR (2983 ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (4695S, Cell Signaling Technology), phospho-ERK1/2 (4370S ...
• The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

  Yang Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... phospho-ERK1/2 (Cell Signaling Technology), or phospho-mTOR (Cell Signaling Technology ...
• IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection

  Curtis J. Pritzl, et al., bioRxiv - Immunology 2022

  Quote: ... phosphorylated ERK1/2 from Cell Signaling; anti-SMAD7(293739 ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... ERK1-2 (Cell Signaling Technology #9107), JAK 2(Cell Signaling Technology # 3230) ...
• YTHDF1 drives intestinal immune response against bacterial infection

  Xin Zong, et al., bioRxiv - Immunology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, 9102), phospho-ERK1/2 (HuaAn ...
• A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

  Damien Detraux, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling 9102), anti-phosphoERK1/2 (Cell Signaling 9101 ...
• Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton

  Sade W. Clayton, Ga I Ban, Cunren Liu, Rosa Serra, bioRxiv - Developmental Biology 2020

  Quote: ... ERK1/2 Catalog #4695S (Cell Signaling), pp38 Catalog #9211S (Cell Signaling) ...
• Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/P38 signaling

  Jamie L. Grit, et al., bioRxiv - Genomics 2020

  Quote: ... phospho-ERK1/2 (Cell Signaling #9101), and β-Actin (Cell Signaling #3700) ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling Technology, 4695), pAKT(Thr308 ...
• FGFR Signaling Coordinates the Balance Between Glycolysis and Fatty Acid β-Oxidation in Lymphatic Endothelial Cells

  Hongyuan Song, Jie Zhu, Longhou Fang, Pengchun Yu, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, 4695), CPT1A (Abcam ...
• Nutrient Sensing Receptor GPRC6A Regulates mTORC1 Signaling and Tau Biology

  Chao Ma, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERK1/2 (Cell Signaling Tech, #9102S), ERK1/2 pT202/Y204 (Cell Signaling Tech ...
• MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

  Célia Guérin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2-Phospho (Cell Signaling #9101), GAPDH (Santa Cruz #Sc-32233/6c5) ...
• Membrane-type 1 matrix metalloproteinase (MMP-14) modulates tissue homeostasis by a non-proteolytic mechanism

  Mukundan Attur, et al., bioRxiv - Cell Biology 2019

  Quote: ... total ERK1/2 antibody: p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (Cell Signaling Technology, cat. # 4695), dilution ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK1/2 (Cell Signaling, CST4370), and anti–β-actin (Sigma) ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (#4695S, 1:1000, Cell Signaling), p-STAT3 Y705 (#4370S ...
• Satellite cell depletion in early adulthood attenuates muscular dystrophy pathogenesis

  Justin G. Boyer, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Erk1/2 (1:2000, Cell Signaling Technology) and GAPDH (1:500 000 ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... P44/42 Erk1/2 (#9102, Cell signaling), Phospho-p44/42 MAPK (Erk1/2 ...
• Functional analysis of KIT gene structural mutations causing porcine dominant white phenotype by using genome edited mouse models

  Guangjie Sun, et al., bioRxiv - Molecular Biology 2019

  Quote: ... and Phospho-Erk1/2 (#8544; Cell Signaling) were diluting in 1:200 with PBS.
• Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.

  Bongyong Lee, et al., bioRxiv - Cancer Biology 2019

  Quote: ... ERK1/2 (Cell Signaling, catalog no. 4695), and GAPDH (Santa Cruz Biotechnology ...
• Inhibition of the Myocardin-Related Transcription Factor pathway increases efficacy of Trametinib in NRAS-mutant melanoma cell lines

  Kathryn M. Appleton, et al., bioRxiv - Cancer Biology 2019

  Quote: ... total ERK1/2 (Cell Signaling cat# 9102), pMLC (Cell Signaling cat# 3674S) ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... p-Erk1/2 (Cell Signaling Technology #4377), Erk-1/2 (Cell Signaling Technology #9102 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-ERK1/2 (#9102, Cell Signaling), 1:1000 ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... Total ERK1/2 (Cell Signaling Technology #4395), 1:1000 ...
• Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis

  Benjamin Ng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-p-ERK1/2 (4370, Cell Signaling), anti-ERK1/2s (4695 ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-ERK1/2 (4370S, Cell Signaling Technology).
• Targeting Chromatin Effector Pygo2 to Enhance Immunotherapy in Prostate Cancer

  Yini Zhu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-Erk1/2 (Cell Signaling Technology, 4370), p53 (Cell Signaling Technology ...
• Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function

  Weiyi Xu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling Technologies, 9102S), anti-LC3B (Cell Signaling Technologies ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (137F5) (Cell Signaling 4695S) lot 28 ...
• Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34⁺ hematopoietic progenitor cells from apoptosis

  Meaghan H. Hancock, et al., bioRxiv - Microbiology 2020

  Quote: ... P-ERK1/2 (Thr202/Tyr204, Cell Signaling), PARP (Cell Signaling) ...
• Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

  Johanna Lilja, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cat. no. 91025, Cell Signaling), phospho-AKT (Ser473 ...