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• Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer

  Eugine Lee, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pHER2 (Cell Signaling, 2243), HER3 (Cell Signaling ...
• Laminin Receptor Characterization in Acute Myeloid Leukemia: Integrin α7β1 Defines non-Leukemic Stem Cells with Migratory Potential

  Elsa Görsch, et al., bioRxiv - Cancer Biology 2024

  Quote: Protein lysates were prepared from 5x106 cells using cell lysis buffer (Cell Signaling Technology, 9803S) supplemented with protease-phosphatase inhibitor (ThermoFisher ...
• Androgen receptor-negative prostate cancer is vulnerable to SWI/SNF-targeting degrader molecules

  Phillip Thienger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The TCF7L2 antibody (Cell Signaling Technologies, cat# 2569, Lot#5) was used for staining ...
• Microdissected tumor cuboids: a microscale cancer model that retains a complex tumor microenvironment

  Lisa F Horowitz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Antibodies were: active cleaved caspase 3 (1/600, Cell Signaling), Ki-67 (1/1,000 ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... -total ERK1/2 (Cell Signaling Tech #9102), -GAPDH (#4138).
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... phospho-ERK1/2 (Cell Signaling Tech pThr202/pTyr204) (#9101) ...
• Microdissected tumor cuboids: a microscale cancer model that retains a complex tumor microenvironment

  Lisa F Horowitz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-human/mouse cleaved-caspase 3 (1:300; Cell Signaling, 9661). followed by 1:500 546-Donkey/Goat anti-rabbit (or other) ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... DDR1 (D1G6) (Cell Signaling Tech. #5583), P4HA3 (Proteintech #23185-1-AP) ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pDDR1 (Tyr513) (Cell Signaling Tech. #14531), DDR1 (D1G6 ...
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pRPA32/RPA2-Ser8 (Cell Signaling Technology, 54762S), Vinculin (Cell Signaling Technology ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-LAMP1 (Cell Signaling Technologies, D2D11 ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-α-tubulin (Cell Signaling Technology, 3873; 1:10,000 for WB), rat anti-tyrosinated ⍺-tubulin (YL1/2 ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-LAMTOR4 (Cell Signaling Technologies, 12284; 1:1000 for WB), rabbit anti- calreticulin (D3E6 ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti- calreticulin (D3E6) (Cell Signaling Technologies, 12238; 1:1000 for WB), mouse anti-GM130 (H7 ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-OPA1 (Cell Signaling, 67589S), anti-GAPDH (Santa Cruz ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: Antibodies include anti-PINK1 (Cell Signaling, 6946T), anti-Parkin-1 (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-NDP52 (Cell Signaling, 60732T), anti-SQSTM1 (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Mitochondrial potential was assessed using MitoTracker Red CMXRos (Cell Signaling, 9082). For immunofluorescent staining of Tom20 and Ceramide ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-MFN2 (Cell Signaling, 9482S), anti-OPA1 (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Parkin-1 (Cell Signaling, 4211T), anti-NDP52 (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-LC3B (Cell Signaling, 368T), anti-DRP1 (Abcam ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-MFN1 (Cell Signaling, 14739S), anti-MFN2 (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-BNIP3L/Nix (Cell Signaling, 12396T), anti-LC3B (Cell Signaling ...
• Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

  Jody Vykoukal, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-SQSTM1 (Cell Signaling, 8025T), anti-BNIP3L/Nix (Cell Signaling ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERG (Cell Signaling Technology: 97249S); RNA Pol II (Active motif ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti acetyl-Lysine beads were purchased from Cell Signaling Technology. Ultrapure water was prepared from a Millipore purification system ...
• Anti-EGFR aptamer exhibits direct anti-cancer effects in NSCLC cells harboring EGFR L858R mutations

  Brian J. Thomas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies for probing western blots were purchased from Cell Signaling Technology (Danvers, MA; (p)EGFR) ...
• Regulation of fatty acid delivery to metastases by tumor endothelium

  Deanna N. Edwards, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The following primary antibodies were used at 1:1000 dilution: Raptor (Cell Signaling Technology (CST) #2280) ...
• Regulation of fatty acid delivery to metastases by tumor endothelium

  Deanna N. Edwards, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 4×106 cells were fixed in methanol and incubated with anti-pS6 (Ser235/236) rabbit antibody (1:100, Cell Signaling Technology #2211), followed by incubation with cell surface markers and secondary Alexa Fluor 647 goat anti-rabbit (1:200 ...
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... FGFR2 (Cell Signaling Technology, CST11835S).
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pCHK1-S345 (Cell Signaling Technology, CST2348), CHK1 (Abcam ...
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pFGFR2- Tyr653/654 (Cell Signaling Technology, CST3476S), FGFR2 (Cell Signaling Technology ...
• Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

  Jun Tang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Vinculin (Cell Signaling Technology, CST13901), pFGFR2- Tyr653/654 (Cell Signaling Technology ...
• Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

  Camille Dantzer, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rab27a (1:1,000, rabbit, 69295, Cell signaling), CD63 (1:500 ...
• NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

  Abhijit Parolia, et al., bioRxiv - Cancer Biology 2024

  Quote: ... His (Cell Signaling Technologies, Cat#2365). ChIP-seq assays were performed using the following antibodies ...
• NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

  Abhijit Parolia, et al., bioRxiv - Cancer Biology 2024

  Quote: ... NKX3-1 (Cell Signaling Technologies:83700S); FOXA1 N-terminal (Cell Signaling Technologies ...
• NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

  Abhijit Parolia, et al., bioRxiv - Cancer Biology 2024

  Quote: ... GAPDH (Cell Signaling Technologies: 3683); H3K27me3(Millipore ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Aiolos (Cell Signaling Technology: 15103S); Ikaros (Cell Signaling Technology ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... H2BK5ac (Cell Signaling Technology: 12799S); AR (Millipore ...
• Extracellular vesicles within a tumourigenic therapy-induced senescent tumour secretome are able to confer anti-cancer properties

  Matius Robert, et al., bioRxiv - Cancer Biology 2024

  Quote: SA-β-Gal activity was measured using the SA-β-gal staining kit (Cell Signaling Technology, USA) following manufacturer’s protocol ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... NKX3-1 (Cell Signaling Technology:83700S); CCND1 (Abcam ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Vinculin (Cell Signaling Technology: 18799S); GAPDH (Santa Cruz Biotechnology ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Ikaros (Cell Signaling Technology: 14859S).
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... H2BK20ac (Cell Signaling Technology: 34156S); H2BK5ac (Cell Signaling Technology ...
• Extracellular vesicles within a tumourigenic therapy-induced senescent tumour secretome are able to confer anti-cancer properties

  Matius Robert, et al., bioRxiv - Cancer Biology 2024

  Quote: ... fixed cells were washed twice in PBS with 0.5% BSA prior to incubation with 1:500 dilution of phospho-histone H3 antibody conjugated with Alexa Fluor 488 (Cell Signaling Techonology, USA) for 1 h in the dark at room temperature ...
• p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

  Jie Luo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Myc (Cell Signaling Technology: 9402S); KLK3/PSA (Dako ...
• A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival

  Jacob Duran, et al., bioRxiv - Cell Biology 2024

  Quote: Antibodies from Cell Signaling Technology were Phospho-eIF2α (Ser51)(1:1000 for WB) ...
• SLC25A46 is in contact with lysosomes and plays a role in mitochondrial cholesterol homeostasis

  Jana Schuettpelz, et al., bioRxiv - Cell Biology 2024

  Quote: ... 4E-BP (Cell Signaling; 9644S), Cav1 (BD bioscience ...
• SLC25A46 is in contact with lysosomes and plays a role in mitochondrial cholesterol homeostasis

  Jana Schuettpelz, et al., bioRxiv - Cell Biology 2024

  Quote: ... MFN2 (Cell Signaling; 11925S), MFN1 (Cell Signaling ...
• Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

  Josephine G. M. Strijker, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Membranes were incubated at 4°C overnight in MIF (Cell Signaling; #87501; 1:1000), MDK (Santa Cruz ...