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1 - 50 of 244 citations for Recombinant Rat VEGFA Protein since 2019

• Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease

  Seth D. Reighard, et al., bioRxiv - Immunology 2020

  Quote: ... 1 μg of recombinant murine IL-2 was incubated overnight with 10 μg rat IgG2a (BioXCell) in 200 μL HBSS ...
• Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers

  Hannah A. Pizzato, et al., bioRxiv - Immunology 2023

  Quote: ... rat IgG2b (BioXCell), CD8 (clone YTS169.4 ...
• Pulmonary natural killer cells control neutrophil intravascular motility and response to acute inflammation

  J. Secklehner, et al., bioRxiv - Immunology 2019

  Quote: ... Rat-IgG (2A3, BioXcell) and Hamster-IgG (Life Technologies ...
• Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion

  Sang Jun Han, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or rat IgG (BioXCell, catalog number ...
• Tumor expressed CD95 causes suppression of anti-tumor activity of NK cells in a model of triple negative breast cancer

  Abdul S. Qadir, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or control rat IgG2a (BioXCell) both in 100 μl ...
• Human Microbial Transplant Restores T Cell Cytotoxicity and Anti-Tumor Response to PD-L1 Blockade in Gnotobiotic Mice

  Joshua N. Borgerding, et al., bioRxiv - Immunology 2020

  Quote: ... or isotype (rat IgG2b, BioXcell) by i.p ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Purified rat IgG2a (2A3; BioXCell) and/or rat IgG2b (LTF2 ...
• Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment

  Alba Nicolas-Boluda, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or isotype control (rat IgG2a; BioXCell) were started when tumors reached 80 −100 mm3 size ...
• A critical role for B cells in cancer immune surveillance

  Kavita Rawat, Anita Tewari, Claudia V. Jakubzick, bioRxiv - Cancer Biology 2020

  Quote: ... (clone RA3.3A1/6.1 Rat IgM, BioXcell) and 1 mg anti-B220 ...
• Keratinocyte-tethering modification for biologics enables location-precise treatment in mouse vitiligo

  Ying-Chao Hsueh, et al., bioRxiv - Immunology 2022

  Quote: ... a rat IgG1 isotype antibody (BioXCell), and purified anti-IFNγ and BsAb were biotinylated by EZ-Link Sulfo-NHS-SS-Biotin (ThermoFisher ...
• Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environment

  Vivien Maltez, et al., bioRxiv - Immunology 2022

  Quote: ... rat IgG2a (2A3; BioXcell; 200 μg) was used ...
• The antibody-based delivery of interleukin-12 to solid tumors boosts NK and CD8⁺ T cell activity and synergizes with immune check-point inhibitors

  Emanuele Puca, et al., bioRxiv - Cancer Biology 2019

  Quote: ... 250μg rat anti-CD8 (YTS169.4, BioXCell) and 250μg rat anti-CD4 (GK1.5 ...
• Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy

  Aleksandar Murgaski, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or rat IgG2a (clone 2A3: BioXCell) was administered IP in a volume of 100 µL HBSS daily starting 24 hours prior to αCD40 treatment and continuing until the end of the experiment.
• Cooperative phagocytosis underlies macrophage immunotherapy of solid tumours and initiates a broad anti-tumour IgG response

  Jason C. Andrechak, et al., bioRxiv - Bioengineering 2022

  Quote: ... isotype control rat IgG2a (BioXCell, BE0089), anti-mouse SIRPα clone P84 (BioLegend 144004) ...
• Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

  Raquel Furtado, et al., bioRxiv - Immunology 2020

  Quote: ... of polyclonal rat IgG (BioXcell; isotype) or anti-LAG-3 (clone C9B7W ...
• B cell receptor induced IL-10 production from neonatal CD19+CD43- cells depends on STAT5 mediated IL-6 secretion

  Jiro Sakai, et al., bioRxiv - Immunology 2022

  Quote: ... InVivoMAb rat IgG2b (LTF-2, BioXcell), InVivo polyclonal Armenian hamster IgG (BioXcell) ...
• Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environment

  Vivien Maltez, et al., bioRxiv - Immunology 2022

  Quote: ... rat IgG2a (2A3; BioXcell; 200 μg) was used ...
• Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environment

  Vivien Maltez, et al., bioRxiv - Immunology 2022

  Quote: ... rat IgG2a (2A3; BioXcell; 200 μg) was used ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and/or rat IgG2b (LTF2; BioXCell) were used as control.
• Prolonged T cell – DC macro-clustering within lymph node microenvironments initiates Th2 cell differentiation in a site-specific manner

  Miranda R. Lyons-Cohen, et al., bioRxiv - Immunology 2023

  Quote: ... 100µg rat IgG2a isotype control (BioXcell), 100µg anti-CD28 (clone 37.51 ...
• Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis

  Lara M. Oberkircher, et al., bioRxiv - Immunology 2024

  Quote: ... Rat IgG2a (clone 2A3, BioXcell, US) was used as isotype control for 1A8.
• Rapid activation of IL-2 receptor signaling by CD301b⁺ DC-derived IL-2 dictates the outcome of helper T cell differentiation

  Naoya Tatsumi, et al., bioRxiv - Immunology 2023

  Quote: ... Rat IgG2a isotype control (2A3, BioXcell) mAb was injected to make the amount of mAbs equal across different groups.
• De-glycosylated non-structural protein 1 enhances dengue virus clearance by limiting PD-L1/PD-1 mediated T cell apoptosis

  Fakhriedzwan Idris, et al., bioRxiv - Microbiology 2024

  Quote: ... or rat IgG2b isotype control (BioXCell) were administered ip ...
• De-glycosylated non-structural protein 1 enhances dengue virus clearance by limiting PD-L1/PD-1 mediated T cell apoptosis

  Fakhriedzwan Idris, et al., bioRxiv - Microbiology 2024

  Quote: ... or rat IgG2b isotype control (BioXCell) was administered ip ...
• Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

  Ming Ji, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and rat anti-PD1 antibody (BioXCell, BE0146) were given intraperitoneally at a dose of 200 μg per mouse on day 4 after cell inoculation ...
• Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3

  Rémi Porte, et al., bioRxiv - Immunology 2022

  Quote: ... or control isotype (InVivoPlus rat IgG2a; BioXcell). Blocking of P-selectin was realized by treating intraperitoneally with 50 µg/100 µl of anti-CD62P depleting antibody (rat RB40.34 NA/LE ...
• Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

  Kwan Ho Tang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 25ug of rat IgG2a (Clone 2A3, Bioxcell) or anti-mouse Ly6G antibody (Clone 1A8 ...
• The antibody-based delivery of interleukin-12 to solid tumors boosts NK and CD8⁺ T cell activity and synergizes with immune check-point inhibitors

  Emanuele Puca, et al., bioRxiv - Cancer Biology 2019

  Quote: ... and 250μg rat anti-CD4 (GK1.5, BioXCell). In the Lewis Lung model ...
• Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection

  Tejram Sahu, et al., bioRxiv - Immunology 2020

  Quote: ... rat anti-CD4 (clone GK 1.5, BioXCell) monoclonal antibodies or isotype control (LTF-2 ...
• B cell receptor induced IL-10 production from neonatal CD19+CD43- cells depends on STAT5 mediated IL-6 secretion

  Jiro Sakai, et al., bioRxiv - Immunology 2022

  Quote: ... InVivoPlus rat IgG1 (HRPN, BioXcell, Lebanon, NH), InVivoMAb rat IgG2b (LTF-2 ...
• The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2

  Selim Chaib, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or rat IgG (IgG2a isotype, BioXCell #BE0089) and euthanized at week 13 ...
• PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance

  Chun Wai Wong, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or rat isotype control antibody IgG2a (BioXCell) in 100 µL InVivoPure pH 7.0 Dilution Buffer (BioXCell ...
• Single-cell level temporal profiling of tumour-reactive T cells under immune checkpoint blockade

  Jehanne Hassan, et al., bioRxiv - Immunology 2022

  Quote: ... or Rat IgG2A Control (clone 2A3, BioxCell) was administered on days 14 and 16 ...
• A Type 2 Innate Lymphoid Cell-Interleukin 9 Circuit Induces Paneth Cell Metaplasia and Small Intestinal Remodeling

  Cheng-Yin Yuan, et al., bioRxiv - Immunology 2022

  Quote: ... Anti-CD4 (clone GK1.5, rat IgG2b) (BioXCell) and rat IgG isotype antibody (Jackson ImmunoResearch ...
• Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

  Ray Pillai, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or isotype control (rat IgG2a, BioXcell #BE0089) intraperitoneally 200 ug three times a week ...
• Tumor cell-derived lactic acid inhibits the interaction of PD-L1 protein and PD-L1 antibody in the PD-L1/PD-1 blockade therapy-resistant tumor

  Wonkyung Oh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or control rat IgG (Bio X Cell) was injected intraperitoneally on days 6 ...
• Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

  Miho Tanaka, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and rat IgG2a isotype control (2A3; BioXCell) at 200μg per antibody per dose ...
• A novel combination of chemotherapy and immunotherapy controls tumor growth in mice with a human immune system

  Aude Burlion, et al., bioRxiv - Immunology 2019

  Quote: ... rat IgG2b, LTF-2) and anti-Gr1 mAb (rat IgG2b, RB6-8C5) were purchased from BioXcell (West Lebanon, NH, USA). The MT807R1 recombinant Ig consisting of rhesus IgG1k constant regions and CDRs derived from the anti-human CD8 antibody M-T807 grafted into rhesus variable framework regions and was provided by the Nonhuman Primate Reagent Resource (NIH contract HHSN272200900037C and grant RR016001) ...
• Gut regulatory T cells mediate immunological tolerance in Salmonella-infected superspreader hosts by suppressing cytotoxic activity of T cells

  LM Massis, et al., bioRxiv - Immunology 2021

  Quote: ... or isotype-matched control antibody (rat IgG2a isotype control, anti-trinitrophenol, BP0089; rat IgG2b isotype control, anti-keyhole limpet hemocyanin, BE0090, BioXcell) were diluted in PBS and administered on days 22 ...
• The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae

  Michael P. Motley, et al., bioRxiv - Immunology 2020

  Quote: ... mice were injected intraperitoneally with 225ug of Rat anti-mouse Ly6G (1A8) or a control Rat anti-mouse IgG2a (2A3) (BioXcell). Neutrophil depletion was confirmed previously using flow cytometry of lung homogenates (Ly6G+ ...
• Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection

  Rémi Porte, et al., bioRxiv - Immunology 2024

  Quote: ... Control mice were injected with the same amount of isotype control rat antibodies (rat IgG1, clone HRPN, cat # BX-BE0088 from BioXCell and rat IgG2b ...
• Cancer cell CCR2 orchestrates suppression of the adaptive immune response

  Miriam R. Fein, et al., bioRxiv - Cancer Biology 2019

  Quote: ... or control rat IgG2b antibody (Bio X Cell) (Winograd et al. ...
• Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models

  Tobiloba E. Oni, et al., bioRxiv - Cancer Biology 2020

  Quote: Radiolabeling of Rat IgG2A (BioXcell, cat. no. BE0089), TOBi85 and TOBi89 with 89Zr-DFO was performed as previously described [43-45] ...
• Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

  Ming Ji, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Isotype-matched control antibody rat IgG2a (BioXCell, BE0089) and rat anti-PD1 antibody (BioXCell ...
• Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

  Kwan Ho Tang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 400ug of rat IgG2b (Clone LTF-2, Bioxcell), anti-mouse CD4 antibody (Clone GK1.5 ...
• The Siglec-sialic acid-axis is a target for innate immunotherapy of glioblastoma

  Philip Schmassmann, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and isotype control (rat IgG2a, clone 2A3, BioXcell) were administered at 10 mg kg-1 i.p ...
• NR4A3 deficiency in CD8⁺ T cells improves adoptive T cell therapy of cancer

  Livia Odagiu, et al., bioRxiv - Immunology 2023

  Quote: ... or its isotype (BioXcell or Leinco; Rat IgG2b) control at day 7 ...
• Context-specific GITR agonism potentiates anti-PD-L1 and CD40-based immuno-chemotherapy combination in heterogeneous pancreatic tumors

  Chanthirika Ragulan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or rat IgG2b isotype control (Cat - #BE0090, BioXCell); for combination treatment ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... rat IgG1 isotype control (BioXcell, HPRN, Cat #BE0088), rat IgG2b isotype control (BioXcell ...
• Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

  Sharon L. Freshour, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Rat IgG2b (BioXcell, catalog #BE0090, clone LTF-2) was used as isotype control for anti-CD4.