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1 - 10 of 10 citations for Suc [Glu9 since 2019

• ERK signaling licenses SKN-1A/NRF1 for proteasome production and proteasomal stress resistance

  Peng Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... using Suc–Leu–Leu–Val–Try–7-amino-4-methylcoumarin (Suc–LLVY–AMC) (Enzo Life Sciences) as the substrate (Sha and Goldberg 2014) ...
• ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau

  V Paradise, et al., bioRxiv - Neuroscience 2022

  Quote: ... 10 mM Suc-LLVY-AMC (Enzo Life Sciences) was added to the diluted lysate ...
• Gene Expression Modulation by the Linker of Nucleoskeleton and Cytoskeleton Complex Contributes to Proteostasis

  Amir Levine, Danielle Grushko, Ehud Cohen, bioRxiv - Cell Biology 2019

  Quote: ... 10 µl of 250 µM Suc-LLVY-AMC (Enzo Life Sciences, BML-P802-0005) was added to each plate (2 M stock solution in DMSO) ...
• Regression from pathological hypertrophy is sexually dimorphic and stimulus-specific

  Deanna Muehleman, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Suc-LLVY-AMC was used to measure chymotrypsin activity (18μM; Enzo Life Sciences BML-P802). The samples were kept on ice until this point ...
• Syrbactin-class dual constitutive- and immuno-proteasome inhibitor TIR-199 impedes myeloma-mediated bone degeneration in vivo

  Vasudha Tandon, et al., bioRxiv - Biochemistry 2021

  Quote: ... Proteasome peptidase activities from the cell lysates were assayed using fluorogenic peptide substrate Suc-LLVY-AMC (Enzo Life Sciences). The measured activity was normalized against total protein concentration ...
• Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1

  Katarzyna Szymanska, et al., bioRxiv - Molecular Biology 2020

  Quote: Crude proteasomal fractions were prepared from cells 54 and incubated with the 20S fluorophore substrate Suc-LLVY-AMC (Enzo Life Sciences Inc.). Fluorescence of each proteasomal preparation was measured on a Mithras LB940 (Berthold Technologies Inc. ...
• UBA52 is crucial in HSP90 ubiquitylation and neurodegenerative signaling during early phase of Parkinson’s disease

  Shubhangini Tiwari, et al., bioRxiv - Neuroscience 2022

  Quote: ... and tissue lysates as reported by us previously (Gupta, Tiwari, et al. 2021) utilizing trypsin (Z-ARR-AMC) and chymotrypsin (SUC-LLVY-AMC) substrate (Enzo life sciences). Reaction mixtures were incubated for 60 minutes at 37°C in dark and the fluorescence intensity was measured using fluorimeter (Varian Cary Eclipse ...
• Desmin is a modifier of dystrophic muscle features in Mdx mice

  Arnaud Ferry, et al., bioRxiv - Pathology 2019

  Quote: ... trypsin-like and caspase-like activities of the 20S catalytic core were assayed 36 using the fluorogenic substrates N-Succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin (Suc-LLVY-AMC, Enzo Life Sciences, Villeurbanne, France), Bz-Val-Gly-Arg-7-amino-4-methylcoumarin (Bz-VGR-AMC ...
• The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity

  Sinem Yılmaz, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 1 mM DTT for 10 min (Karademir et al., 2018) and then with fluorogenic substrates Suc-LLVY-AMC (Enzo Life Sciences, BML-P802-0005), Z-LLE-AMC (Enzo Life Sciences ...
• Hsf1 and the molecular chaperone Hsp90 support a “rewiring stress response” leading to an adaptive cell size increase in chronic stress

  Samarpan Maiti, et al., bioRxiv - Cell Biology 2023

  Quote: ... in a 96-well opaque bottom white plate and 50 µM N-succinyl-Leu-Leu-Val-Tyr-7-amino-4-methyl-coumarin (suc-LLVY-AMC) (Enzo Life Sciences, #BML-P802-0005) was added to each well ...