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1 - 11 of 11 citations for H2 Q10 siRNA since 2019

• Therapeutic Targeting of TIM-4-L With Engineered T Cells for Acute Myeloid Leukemia

  Brandon Cieniewicz, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Five- to 7-week-old female NSG MHC dKO mice (NOD.Cg-Prkdcscid H2-K1b-tm1Bpe H2-Ab1g7-em1Mvw H2-D1b-tm1Bpe Il2rgtm1Wjl/SzJ) were obtained from Jackson Laboratory (Cat# 205216, RRID: IMSR_JAX:025216).
• A biomimetic five-module chimeric antigen receptor (^5MCAR) designed to target and eliminate antigen-specific T cells

  Shio Kobayashi, et al., bioRxiv - Bioengineering 2020

  Quote: ... B10.A-H2 H2-T18 /SgSnJ (B10.A) mice were purchased from Jackson Laboratory and 5c.c7 TCR Tg × Rag2−/− [B10.A-Rag2tm1Fwa H2-T18a Tg (Tcra5CC7,Tcrb5CC7)lwep] mice were purchased from Taconic ...
• Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance

  Yannick D. Muller, et al., bioRxiv - Immunology 2021

  Quote: ... and NOD.Cg Prkdcscid Il2rgtm1Wjl/ Tg(HLA-DRB1)31Dmz/SzJ/H2-Ab1tm1Gru x NOD.Cg-Tg(HLA-A/H2-D/B2M)1Dvs/SzJ (A2-NSG) were obtained from Jackson Laboratories. For GvHD induction ...
• Surface-associated antigen induces B-cell permeabilization and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

  Fernando Y. Maeda, et al., bioRxiv - Cell Biology 2021

  Quote: ... B10.BR-H2k2 H2-T18a/SgSnJJrep (Jackson Laboratories), and F1 of B10.BR-H2k2 H2-T18a/SgSnJJrep x MD4 mice using a previously published protocol (Miller et al ...
• Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

  Darren B. McAffee, et al., bioRxiv - Biophysics 2021

  Quote: The mice used in this study were the cross of (B10.Cg-Tg(TcrAND)53Hed/J)x(B10.BR-H2k2 H2-T18a/SgSnJ) from Jackson Laboratory. All animal work was performed with prior approval by the IACUC committee ...
• Tissue-resident memory CD8 T-cell responses elicited by a single injection of a multi-target COVID-19 vaccine

  V. Gauttier, et al., bioRxiv - Immunology 2020

  Quote: B6.Cg-Immp2lTg(HLA-A/H2-D)2Enge/J (HLA-A2.1) transgenic mice (JAX # 004191, The Jackson Laboratory, Bar Harbor, USA) received a single subcutaneous injection of 6 SARS-CoV-2 peptides (50μg each ...
• Integration of exogenous and endogenous co-stimulatory signals by CAR-Tregs

  Isaac Rosado-Sánchez, et al., bioRxiv - Immunology 2022

  Quote: ... HLA-A2+ Bl/6 mice (B6.Cg-Tg(HLA-A/H2-D)2Enge/J) and OTII Bl6 mice (B6.Cg-Tg(TcraTcrb)425Cbn/J) were purchased from Jackson Laboratories and bred in-house under specific pathogen-free conditions.
• Allosteric Inhibition of the T Cell Receptor by a Designed Membrane Ligand

  Yujie Ye, et al., bioRxiv - Biophysics 2022

  Quote: ... T cells from the lymph nodes and spleens were harvested from (B10.Cg-Tg(TcrAND)53Hed/J) × (B10.BR-H2k2 H2-T18a/SgSnJ) hybrid mice (Jackson Laboratory) and kept in T cell culture medium (day 1) ...
• Differential Roles of Kinetic On- and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab’-DNA Ligand

  Kiera B. Wilhelm, Anand Vissa, Jay T. Groves, bioRxiv - Biophysics 2024

  Quote: ... bred as a cross of B10.Cg-Tg(TcrAND)53Hed/J X B10.BR-H2k2 H2-T18a/SgSnJ from Jackson Laboratory. Polyclonal primary murine T cells were a gift from the Art Weiss lab at UCSF.
• Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice

  Donita L. Garland, et al., bioRxiv - Neuroscience 2020

  Quote: ... Efemp1R345W/R345W mice were crossed with homozygous C5-/- mice (B10.D2-Hc0 H2d H2-T18c/o2SnJ) purchased from Jackson Laboratory (JAX stock #000461), which have a 2 base deletion that creates a STOP codon and results in a non-functional protein ...
• Height, but not binding epitope, affects the potency of synthetic TCR agonists

  Kiera B. Wilhelm, et al., bioRxiv - Biophysics 2021

  Quote: ... T cells were harvested from hemizygous transgenic mice from the cross of (B10.Cg-Tg(TcrAND)53Hed/J) x (B10.BR-H2k2 H2-T18a/SgSnJ) strains (The Jackson Laboratory, Bar Harbor, ME) and activated by moth cytochrome c peptide (MCC88-103 ...