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9501 - 9550 of 10000+ citations since 2019

• Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135

  José González-Martínez, et al., bioRxiv - Cell Biology 2020

  Quote: ... Trp53 knockout mice were obtained from Jackson Laboratories (B6.129S2-Trp53tm1Tyj/J ...
• Mitochondrial-Encoded Peptide MOTS-c is an Exercise-Induced Regulator of Aging Metabolic Homeostasis and Physical Capacity

  Joseph C. Reynolds, et al., bioRxiv - Cell Biology 2020

  Quote: ... 12-week old male C57BL/6J mice (Jackson Laboratory) and 8- and 18-month old male C57BL/6N mice (National Institute on Aging ...
• Zika virus alters centrosome organization to suppress the innate immune response

  Andrew Kodani, et al., bioRxiv - Cell Biology 2020

  Quote: We acquired Cep90tm1.1(KOMP)VlCg (also called Pibf1tm1.1(KOMP)VlCg) heterozygous mice (Jackson Laboratory). Cep90tm1.1(KOMP)VlCg is a deletion of Chr14:99099433-99254493 (GRCm38.p3) ...
• Decreased miR-24-3p potentiates DNA damage responses and increases susceptibility to COPD

  Jessica Nouws, et al., bioRxiv - Cell Biology 2020

  Quote: ... AKR/J mice obtained from Jackson Laboratories and bred in our facility ...
• Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division

  Xiang Zhao, et al., bioRxiv - Cell Biology 2020

  Quote: ... or donkey anti-guinea pig (Alexa 647, Jackson Labs 706-605-148 ...
• SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells

  Katie C. Coate, et al., bioRxiv - Cell Biology 2020

  Quote: ... Kidney from adult NOD.Cg-PrkdcscidIl2rgtm1Wjl/ Sz (NSG) mice ages 12 to 18 weeks (Jackson Laboratory) were isolated ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... and secondary antibodies HRP-coupled anti-mouse or anti-rabbit (GE Healthcare and Jackson Laboratories, 1:5000). The cell cycle analysis was performed using HMLE cells that were fixed in 70% ethanol for 1 h on ice ...
• Rapid tolerance to morphine in the myenteric neurons of the small intestine is independent of β-arrestin-2 and mediated by PKC

  Karan H. Muchhala, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... and female MOR-mCherry mice (The Jackson Laboratory, Bar Harbor, ME) were separately group-housed by genotype with up to five animals per IVC cage in animal-care quarters maintained on a 12-hour light/dark cycle ...
• Corticostriatal Plasticity Established by Initial Learning Persists After Behavioral Reversal

  Sanchari Ghosh, Anthony M Zador, bioRxiv - Neuroscience 2020

  Quote: ... C57 Black6J animals were obtained from Jackson laboratories and housed in a temperature and moisture controlled room with 12-hour light/dark cycle ...
• A Unique Mouse Model of Early Life Exercise Enables Hippocampal Memory and Synaptic Plasticity

  Autumn S. Ivy, et al., bioRxiv - Neuroscience 2020

  Quote: ... originally obtained from Jackson Laboratories and further bred in our animal facilities ...
• Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice

  Huy Pho, et al., bioRxiv - Physiology 2020

  Quote: ... 46 male homozygous B6.BKS(D)-Lepdb/J (db/db) leptin receptor deficient mice from Jackson Laboratory (Bar Harbor, ME, Stock #000697) were used for this study ...
• Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?

  Kimberly F. Young, et al., bioRxiv - Physiology 2020

  Quote: ... Male and female C57Bl6/J mice were purchased from Jackson Laboratories (Bar Harbor, ME). The experimental unit for these studies is a single mouse and all sample sizes ...
• Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat

  Fenfen Li, et al., bioRxiv - Physiology 2020

  Quote: Mice with Utx deletion in Myf5-expressing cells were generated by crossing Utx-floxed mice with Myf5-Cre mice (Tallquist et al., 2000) (Jackson Laboratory, Stock No. 007893) (MUTXKO ...
• Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat

  Fenfen Li, et al., bioRxiv - Physiology 2020

  Quote: ... with Ucp1-Cre mice (Jackson Laboratory, Stock No. 024670)(Kong et al. ...
• Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat

  Fenfen Li, et al., bioRxiv - Physiology 2020

  Quote: Mice with brown adipocyte-specific Utx knockout were generated by crossing Utx-floxed mice (Jackson Lab, stock No. 021926) (Welstead et al. ...
• Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat

  Fenfen Li, et al., bioRxiv - Physiology 2020

  Quote: ... Rosa-Gfp mice (Jackson Laboratory, Stock No. 006148) (Srinivas et al. ...
• Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat

  Fenfen Li, et al., bioRxiv - Physiology 2020

  Quote: C57BL/6J (B6) mice (Jackson Laboratories) were used in some experiments.
• The lateral periaqeductal gray and its role in controlling the opposite behavioral choices of predatory hunting and social defense

  Ignacio Javier Marín-Blasco, et al., bioRxiv - Animal Behavior and Cognition 2020

  Quote: ... n = 10) knock-in mice were acquired from Jackson Laboratories (stocks #016962 and #016963).
• Extracting the Dynamics of Behavior in Decision-Making Experiments

  Nicholas A. Roy, et al., bioRxiv - Neuroscience 2020

  Quote: 101 experimental subjects were C57BL/6J mice obtained from Jackson Laboratory or Charles River ...
• Distinct recruitment of feed-forward and recurrent pathways across higher-order areas of mouse visual cortex

  Jennifer Y. Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... All transgenic mice were heterozygous and bred on a C57/B6J (Jackson Labs #000664) background ...
• VELCRO-IP RNA-seq explores ribosome expansion segment function in translation genome-wide

  Kathrin Leppek, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit polyclonal anti-RPL10A antibody was kindly provided by Mary Ann Handel (The Jackson Laboratory, Bar Harbor, ME, USA).
• Mechanisms underlying neonate specific metabolic effects of volatile anesthetics

  Julia Stokes, et al., bioRxiv - Physiology 2020

  Quote: ... originally obtained from Jackson laboratories (Bar Harbor, ME), or the Ndufs4(KO ...
• Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-induced Weight Gain in Male Mice

  E. Matthew Morris, et al., bioRxiv - Physiology 2020

  Quote: ... C57Bl/6J male mice (#000664, Jackson Laboratory, Bar Harbor, ME, USA) were bred to female homozygous pgc1a floxed mice (#00966 ...
• Temperature and species-dependent regulation of browning in retrobulbar fat

  Fatemeh Rajaii, et al., bioRxiv - Physiology 2020

  Quote: ... mice with Sun1-GFP (Jax Stock #021039, Jackson Labs) reporter mice to allow fate mapping of neural crest-derived cells in orbit ...
• Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo

  Andrea L. Estrada, et al., bioRxiv - Physiology 2020

  Quote: ... All mice were on the C57BL/6J background and originally purchased from Jackson Laboratories. Wild type mice were allowed a 2-week acclimation period prior to commencing studies ...
• Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment

  Ryan M. Marquardt, et al., bioRxiv - Physiology 2020

  Quote: ... Arid1a conditional knockout mice were generated in the C57BL/6 background by crossing Pgrcre/+(27) or LtfiCre/+ (28) (The Jackson Laboratory Stock No: 026030) males with Arid1af/f (29 ...
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... 129S4 mice were obtained from Jackson labs (Jax line# 009104). For behavioral experiments ...
• Mechanical Loading Recovers Bone but not Muscle Lost During Unloading

  Andrew R. Krause, et al., bioRxiv - Physiology 2020

  Quote: Male C57BL/6J mice (Jackson Laboratories, Bar Harbor, ME, USA) were used for all experiments ...
• Effect of the p75 Neurotrophin Receptor on Glycemic Control of Obese Mice during Time-Restricted Feeding

  Brandon Podyma, et al., bioRxiv - Physiology 2020

  Quote: ... Ob/Ob mice were purchased from Jackson Labs (#000632) and genotyped by PCR amplifying (Forward primer ...
• Effect of the p75 Neurotrophin Receptor on Glycemic Control of Obese Mice during Time-Restricted Feeding

  Brandon Podyma, et al., bioRxiv - Physiology 2020

  Quote: ... Ngfr-KO mice were purchased from Jackson Labs (Bar Harbor, ME, USA) (#002213)(19) ...
• Antisense oligonucleotides against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

  Andrew J. Lutkewitte, et al., bioRxiv - Physiology 2020

  Quote: ... C57BL6/J mice (Jackson Laboratory) received retro-orbital injection of either control AAV8-GFP-U6-scramble-shRNA (Vector Biolabs ...
• Soluble RANKL exaggerates hindlimb suspension-induced osteopenia but not muscle protein balance

  Toni L. Speacht, et al., bioRxiv - Physiology 2020

  Quote: Forty male C57BL/6J mice (Jackson Labs; Bar Harbor, ME) that were 16 weeks ± 3 days old at experimental day 0 were used ...
• Antibody-drug conjugates targeting CD45 plus Janus kinase inhibitors effectively condition for allogeneic hematopoietic stem cell transplantation

  Stephen P. Persaud, et al., bioRxiv - Immunology 2020

  Quote: ... All mice were bred within specific-pathogen free colonies at Washington University School of Medicine or purchased from Jackson Laboratories (Bar Harbor, ME) and maintained on ad libitum water and standard chow (LabDiet 5053 ...
• Unique maternal immune and functional microbial profiles during prenatal stress

  Adrienne M. Antonson, et al., bioRxiv - Immunology 2020

  Quote: Nulliparous adult C57BL/6J female mice were acquired from Jackson Laboratories (Bar Harbor, ME) at 10-weeks of age and acclimated to the vivarium at The Ohio State University Wexner Medical Center for a minimum of one week ...
• Focused ultrasound excites neurons via mechanosensitive calcium accumulation and ion channel amplification

  Sangjin Yoo, et al., bioRxiv - Neuroscience 2020

  Quote: ... Cortical tissues were dissected from embryonic day 18 C57BL/6J mice (The Jackson Laboratory). The tissues were rinsed with Hank’s Balanced Salt Solution (VWR ...
• Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1

  Ravi Chopra, et al., bioRxiv - Neuroscience 2020

  Quote: ... ATXN1[82Q] transgenic mice (Burright et al., 1995) were maintained homozygous for the transgene on an FVB/NJ background (Jackson Labs). In all experiments involving ATXN1[82Q] transgenic mice ...
• Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1

  Ravi Chopra, et al., bioRxiv - Neuroscience 2020

  Quote: ... Atxn1154Q knock-in mice (Watase et al., 2002) were maintained on a C57Bl6J background (Jackson labs) by crossing Atxn1154Q/2Q males with Atxn12Q/2Q wild-type females ...
• The role of the hypothalamus in cortical arousal and sleep homeostasis

  Tomoko Yamagata, et al., bioRxiv - Neuroscience 2020

  Quote: The experiments were performed in male and female Gad2-IRES-Cre mice (Jackson Laboratory 019022; B6N.Cg-Gad2tm2(cre)Zjh/J) ...
• Natural food intake patterns do not synchronize peripheral clocks

  Xiaobin Xie, et al., bioRxiv - Physiology 2020

  Quote: ... were purchased from Jackson Laboratories (B6.129S6-Per2tm1Jt/J ...
• T cells are present in non-diabetic islets and accumulate during aging

  Heather C. Denroche, et al., bioRxiv - Physiology 2020

  Quote: Male C57BL/6J mice were obtained from Jackson Laboratories (Strain #000664, Jackson Laboratories, Bar Harbor, ME) and aged up to 24 months at the Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval (Québec ...
• T cells are present in non-diabetic islets and accumulate during aging

  Heather C. Denroche, et al., bioRxiv - Physiology 2020

  Quote: ... High fat diet fed mice (Jackson Laboratories, cat#380050) were fed a 60% fat diet (#D12492 ...
• T cells are present in non-diabetic islets and accumulate during aging

  Heather C. Denroche, et al., bioRxiv - Physiology 2020

  Quote: ... Chow-fed controls (Jackson Laboratories, cat#380056) were fed 10% fat diet (#D12450B ...
• T cells are present in non-diabetic islets and accumulate during aging

  Heather C. Denroche, et al., bioRxiv - Physiology 2020

  Quote: Male C57BL/6J mice were obtained from Jackson Laboratories (Strain #000664 ...
• Subthreshold repertoire and threshold dynamics of midbrain dopamine neuron firing in vivo

  Kanako Otomo, et al., bioRxiv - Neuroscience 2020

  Quote: ... and C57BL/6J (Jackson Laboratories) mice (67 males and 7 females ...
• An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

  Jürgen G. Okun, et al., bioRxiv - Physiology 2020

  Quote: ... was administed to C57Bl/6J and BKS-db/db mice (Jackson Laboratories, USA). More specifically ...
• Antisense oligonucleotides against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

  Andrew J. Lutkewitte, et al., bioRxiv - Physiology 2020

  Quote: ... Mogat1 floxed mice were crossed with mice expressing the Cre recombinase transgene under the control of the albumin promoter (Jackson Laboratory, B6.Cg-Speer6-ps1Tg (Alb-cre) 21Mgn/J) ...
• Antisense oligonucleotides against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1

  Andrew J. Lutkewitte, et al., bioRxiv - Physiology 2020

  Quote: ... HFD-fed male C57BL/6J mice were obtained from Jackson Laboratory after 12-weeks of diet ...
• Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models

  Jessica Sook Yuin Ho, et al., bioRxiv - Microbiology 2020

  Quote: ... 5-10 week old female B6.Cg-Tg(K18-ACE2)2Prlmn/J (K18-hACE2) mice purchased from Jackson Laboratories (Bar Harbor, ME) were anesthetized by an intraperitoneal injection of 90mg/kg Ketamine and 2 mg/kg xylazine ...
• Ontogeny and function of the circadian clock in intestinal organoids

  Andrew E. Rosselot, et al., bioRxiv - Molecular Biology 2020

  Quote: HIOs were transplanted into the kidney capsule of immune-deficient NOD-SCID IL-2Rγnull (NSG) (Jackson Laboratories) mice ...
• Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle

  Miki Jishage, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Gdown1flox/flox mice were crossed with transgenic mice expressing Cre under the control of the albumin promoter (Alb-Cre mice) (Stock Number 003574, The Jackson Laboratory). To generate p53 and Gdown1 double knockout (DKOAlb-cre ...